Search Results - "Kokotos, Christoforos G"
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1
Green Metal‐Free Photochemical Hydroacylation of Unactivated Olefins
Published in Angewandte Chemie International Edition (20-01-2020)“…Direct alkylation of C(sp2)−H bonds to convert an aldehyde into a ketone is a notorious transformation, due to the laborious challenge of the formation of…”
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2
Photoinitiated Thiol‐Ene “Click” Reaction: An Organocatalytic Alternative
Published in Advanced synthesis & catalysis (01-01-2017)“…The thiol‐ene coupling (TEC) reaction has attracted a lot of scientific attention during the last years, particularly in the fields of polymers, materials and…”
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3
2,2,2-Trifluoroacetophenone: An Organocatalyst for an Environmentally Friendly Epoxidation of Alkenes
Published in Journal of organic chemistry (16-05-2014)“…A cheap, mild, fast, and environmentally friendly oxidation of olefins to the corresponding epoxides is reported using polyfluoroalkyl ketones as efficient…”
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4
Construction of Tertiary Alcohols Bearing Perfluoroalkyl Chains Catalyzed by Prolinamide-Thioureas
Published in Journal of organic chemistry (20-01-2012)“…A systematic study to evaluate the ability of various organocatalysts to catalyze the aldol reaction between acetone and 2,2,2-trifluoromethyl-1-phenylethanone…”
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5
Aldehydes as powerful initiators for photochemical transformations
Published in Beilstein journal of organic chemistry (23-04-2020)“…Photochemistry, the use of light to promote organic transformations, has been known for more than a century but only recently has revolutionized the way modern…”
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6
One-Pot Synthesis of Ureas from Boc-Protected Amines
Published in Journal of organic chemistry (16-05-2014)“…A practical one-pot synthesis of ureas is described. Boc-protected amines can be transformed into nonsymmetrical and symmetrical disubstituted and…”
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7
Cyrene: a bio-based solvent for the Mizoroki-Heck reaction of aryl iodides
Published in Organic & biomolecular chemistry (04-01-2023)“…The development of greener and more sustainable methods, as well as the adaptation of already existing protocols to more environmentally friendly procedures,…”
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8
Metal‐free Photochemical Atom Transfer Radical Addition (ATRA) of BrCCl3 to Alkenes
Published in European journal of organic chemistry (08-01-2021)“…A simple, photochemical, and metal‐free protocol for the atom transfer radical addition (ATRA) of bromotrichloromethane onto various alkenes is described…”
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9
Enantioselective Organocatalytic Synthesis of 2‑Oxopiperazines from Aldehydes: Identification of the Elusive Epoxy Lactone Intermediate
Published in Organic letters (18-11-2016)“…An organocatalytic linchpin catalysis approach was envisaged to convert simple aldehydes into enantioenriched 2-oxopiperazines. A four-step reaction sequence…”
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10
Green and sustainable approaches for the Friedel-Crafts reaction between aldehydes and indoles
Published in Beilstein journal of organic chemistry (22-02-2024)“…The synthesis of indoles and their derivatives, more specifically bis(indolyl)methanes (BIMs), has been an area of great interest in organic chemistry, since…”
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11
Visible-Light-Mediated Catalytic Hydroacylation of Dialkyl Azodicarboxylates by Graphite Flakes
Published in Organic letters (07-04-2017)“…A novel and efficient metal-free catalyzed hydroacylation of dialkyl azodicarboxylates is reported. Graphite flakes were found to be the most efficient…”
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12
4‑Fluoro and 4‑Hydroxy Pyrrolidine-thioxotetrahydropyrimidinones: Organocatalysts for Green Asymmetric Transformations in Brine
Published in Journal of organic chemistry (05-06-2015)“…The synthesis of both trans- and cis-diastereomers of pyrrolidinine-thioxotetrahydropyrimidinone bearing either a fluorine or a hydroxyl group was…”
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13
(Thio)urea-mediated synthesis of functionalized six-membered rings with multiple chiral centers
Published in Beilstein journal of organic chemistry (10-03-2016)“…Organocatalysis, now running its second decade of life, is being considered one of the main tools a synthetic chemist has to perform asymmetric catalysis. In…”
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14
Photocatalytic Atom Transfer Radical Addition to Olefins Utilizing Novel Photocatalysts
Published in Molecules (Basel, Switzerland) (26-04-2019)“…Photocatalysis is a rapidly evolving area of research in modern organic synthesis. Among the traditional photocatalysts, metal-complexes based on ruthenium or…”
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15
Primary Amine‐Thioureas based on tert‐Butyl Esters of Natural Amino Acids as Organocatalysts for the Michael Reaction
Published in Advanced synthesis & catalysis (01-06-2009)“…A new class of primary amine‐thioureas based on tert‐butyl esters of (S)‐α‐amino acids and (1S,2S)‐diphenylethylenediamine was synthesized and their activity…”
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16
Organocatalytic asymmetric domino Michael-Henry reaction for the synthesis of substituted bicyclo[3.2.1]octan-2-ones
Published in Chemical communications (Cambridge, England) (01-01-2013)“…The first organocatalytic asymmetric reaction between 1,4-cyclohexanedione and nitroalkenes has been studied, affording bicyclo[3.2.1]octane derivatives…”
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17
Enantioselective Organocatalytic Enamine C−H Oxidation/Diels‐ Alder Reaction
Published in Advanced synthesis & catalysis (16-04-2019)“…α,β‐unsaturated aldehydes have been traditionally used in LUMO lowering asymmetric aminocatalysis (iminium catalysis), while the use of saturated aldehydes as…”
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18
Sulfonamides of homoproline and dipeptides as organocatalysts for Michael and aldol reactions
Published in Tetrahedron (14-02-2009)“…Sulfonamides of the non-natural amino acid homoproline and the dipeptide Pro–Phe were synthesised and evaluated for their catalytic activity in Michael and…”
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19
An Asymmetric Michael Addition of α,α-Disubstituted Aldehydes to Maleimides Leading to a One-Pot Enantioselective Synthesis of Lactones Catalyzed by Amino Acids
Published in Organic letters (17-05-2013)“…A cheap and fast construction of both enantiomers of substituted succinimides is reported. α- or β-amino acids, such as β-phenylalanine and α-tert-butyl…”
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20
Green Organocatalytic Synthesis of Isoxazolines via a One-Pot Oxidation of Allyloximes
Published in Organic letters (06-01-2017)“…A green, sustainable, organocatalytic, and efficient synthesis of isoxazolines from allyloximes was developed. A 2,2,2-trifluoroacetophenone-catalyzed…”
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