Search Results - "Kokoszka, Malgorzata"
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Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3
Published in The Journal of biological chemistry (31-08-2018)“…Mixed-lineage kinase 3 (MLK3; also known as MAP3K11) is a Ser/Thr protein kinase widely expressed in normal and cancerous tissues, including brain, lung,…”
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Journal Article -
2
Mapping protein-protein interactions with phage-displayed combinatorial peptide libraries and alanine scanning
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2015)“…One avenue for inferring the function of a protein is to learn what proteins it may bind to in the cell. Among the various methodologies, one way for doing so…”
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Journal Article -
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Mapping Protein-Protein Interactions with Combinatorial Peptides
Published 01-01-2016“…Since its invention in 1985 by George Smith, phage display has been an extremely beneficial tool in proteomics and drug discovery. Screening of phage-displayed…”
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Dissertation -
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Design of a flexible cell-based assay for the evaluation of heat shock protein 70 expression modulators
Published in Assay and drug development technologies (01-06-2011)“…Heat shock protein 70 (Hsp70) is a chaperone protein that helps protect against cellular stress, a function that may be co-opted to fight human diseases. In…”
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Journal Article -
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Fetal programming of adult metabolism in rats
Published 01-01-2009“…The importance of the prenatal period for adult health is underscored by epidemiological correlations between prematurity and diseases such as coronary heart…”
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Dissertation -
6
Fetal programming of adult metabolism in rats
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Dissertation