Search Results - "Kokil, Ganesh R."
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Inorganic/organic combination: Inorganic particles/polymer composites for tissue engineering applications
Published in Bioactive materials (01-06-2023)“…Biomaterials have ushered the field of tissue engineering and regeneration into a new era with the development of advanced composites. Among these, the…”
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Pharmacology and chemistry of diabetes mellitus and antidiabetic drugs: a critical review
Published in Current medicinal chemistry (01-12-2010)“…Diabetes mellitus, an epidemic metabolic disorders characterized by high blood glucose level associated with various macrovascular and microvascular…”
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Bioprecursor prodrugs: molecular modification of the active principle
Published in Mini reviews in medicinal chemistry (01-12-2010)“…A large number of therapeutic medications have undesirable properties that may generate pharmacological, pharmaceutical, or pharmacokinetic barriers in…”
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Rheumatoid arthritis: a new challenge in coming era
Published in Mini reviews in medicinal chemistry (01-02-2010)“…Rheumatoid arthritis (RA) is mainly an auto-immune disease characterized by inflammation in joints. 1 in 50 people develop RA at some stage and at any age…”
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Type 2 Diabetes Mellitus: Limitations of Conventional Therapies and Intervention with Nucleic Acid-Based Therapeutics
Published in Chemical reviews (10-06-2015)“…Kokil et al examine limitations of conventional therapies and intervention with nucleic acid-based therapeutics with regard to type 2 diabetes mellitus…”
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Microencapsulated islet-like microtissues with toroid geometry for enhanced cellular viability
Published in Acta biomaterialia (01-10-2019)“…[Display omitted] Transplantation of immuno-isolated islets is a promising strategy to restore insulin-secreting function in patients with Type 1 diabetes…”
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Self-assembling asymmetric peptide-dendrimer micelles – a platform for effective and versatile in vitro nucleic acid delivery
Published in Scientific reports (19-03-2018)“…Despite advancements in the development of high generation cationic-dendrimer systems for delivery of nucleic acid-based therapeutics, commercially available…”
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Oseltamivir: a first line defense against swine flu
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-07-2010)“…Oseltamivir (has known by its brand name 'Tamiflu') is a prodrug, requiring ester hydrolysis for conversion to the active form, Oseltamivir carboxylate…”
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Development of a hybrid peptide dendrimer micellar carrier system and its application in the reformulation of a hydrophobic therapeutic agent derived from traditional Chinese medicine
Published in RSC advances (18-01-2019)“…The discovery that a cane toad poison-derived steroid, bufalin can significantly impact cancer cell proliferation supports its potential use in cancer therapy…”
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Novel chromeneimidazole derivatives as antifungal compounds: synthesis and in vitro evaluation
Published in Acta Poloniae pharmaceutica (01-07-2010)Get full text
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On-Demand Activatable Peroxidase-like Porous Silicon–Gold Nanozymes for Colorimetric Sensing
Published in ACS applied nano materials (09-02-2024)“…Nanozymes have shown promise in a range of applications including food safety, environmental monitoring, clinical diagnostics, and bioimaging. However, more…”
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Cerium Oxide Nanoparticles with Entrapped Gadolinium for High T 1 Relaxivity and ROS-Scavenging Purposes
Published in ACS omega (21-06-2022)“…Gadolinium chelates are employed worldwide today as clinical contrast agents for magnetic resonance imaging. Until now, the commonly used linear contrast…”
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Cerium Oxide Nanoparticles with Entrapped Gadolinium for High T1 Relaxivity and ROS-Scavenging Purposes
Published in ACS omega (07-06-2022)“…Gadolinium chelates are employed worldwide today as clinical contrast agents for magnetic resonance imaging. Until now, the commonly used linear contrast…”
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QSAR studies of phthalazinones: novel inhibitors of poly (ADP-ribose) polymerase
Published in Medicinal chemistry research (01-09-2011)“…Over activation of poly (ADP-ribose) polymerase has been involved in the pathogenesis of several diseases including stroke, myocardial infarction, diabetes,…”
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