Search Results - "Koketsu, Mamoru"
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Recent developments in the synthesis of biologically relevant selenium-containing scaffolds
Published in Coordination chemistry reviews (15-05-2017)“…[Display omitted] •Se-containing organic scaffolds synthesis.•Se-containing heterocycles synthesis.•Se-containing bioactive organic scaffolds…”
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Synthesis of Seleno‐Heterocycles via Electrophilic/Radical Cyclization of Alkyne Containing Heteroatoms
Published in Advanced synthesis & catalysis (08-09-2020)“…containing heterocyclic scaffolds by virtue of their interesting reactivities and a broad range of applications in the medicinal and materials chemistry. This…”
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3
Biologically significant selenium-containing heterocycles
Published in Coordination chemistry reviews (01-12-2011)“…► Selenium represents an essential element for organisms. ► As selenium containing is very important for the organism, various diseases can result from…”
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Synthesis of indole-2-, 3-, or 5-substituted propargylamines via gold(III)-catalyzed three component reaction of aldehyde, alkyne, and amine in aqueous medium
Published in Tetrahedron (16-09-2013)“…A simple and efficient route to indole-2-, 3-, or 5-substituted propargylamines by three component-coupling of substituted indole carboxaldehydes, terminal…”
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5
Synthesis of 2,8-Dioxabicyclo[3.3.1]nonane Derivatives via a Sequential Knoevenagel Condensation and Hetero-Diels–Alder Reaction in an Aqueous Medium
Published in Journal of organic chemistry (15-11-2013)“…Utilizing aldehyde-substituted vinylogous carbonates and 1,3-diketones, a simple protocol is presented for the synthesis of 2,8-dioxabicyclo[3.3.1]nonane…”
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Isolation and analysis of polysaccharide showing high hyaluronidase inhibitory activity in Nostochopsis lobatus MAC0804NAN
Published in Journal of bioscience and bioengineering (01-03-2016)“…An active substance with high hyaluronidase inhibitory effect was isolated from the edible cyanobacterium Nostochopsis lobatus MAC0804NAN strain and…”
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7
Synthesis, Characterization, and Antileukemic Properties of Naphthoquinone Derivatives of Lawsone
Published in ChemMedChem (01-08-2015)“…Naphthoquinones are considered privileged structures for anticancer drug molecules. The Heck reaction of 2‐hydroxy‐1,4‐naphthoquinone (lawsone) with…”
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A New Depsidone from Teloschistes flavicans and the Antileukemic Activity
Published in Journal of Oleo Science (01-01-2020)“…Lichens produce a variety of secondary metabolites that could be potential sources of pharmaceutically useful chemicals. However, only a limited number of…”
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Application of bis-2-(trimethylsilyl)ethyl diselenide to the synthesis of selenium-containing amino acid derivatives
Published in Tetrahedron (19-10-2017)“…Selenium-containing amino acids play a pivotal role as biomaterials for the synthesis of Se-dependent enzymes and repair proteins. Especially, selenocysteine…”
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An efficient method for the synthesis of selenium modified nucleosides: its application in the synthesis of Se-adenosyl-L-selenomethionine (SeAM)
Published in Organic & biomolecular chemistry (01-01-2015)“…In this paper, we report that a versatile method for the synthesis of 5'-selenium modified nucleosides has been explored on the basis of a…”
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Sentulic acid isolated from Sandoricum koetjape Merr attenuates lipopolysaccharide and interferon gamma co-stimulated nitric oxide production in murine macrophage RAW264 cells
Published in Bioorganic & medicinal chemistry letters (01-12-2018)“…A seco-triterpenoid, sentulic acid isolated from Sandoricum koetjape Merr attenuated lipopolysaccharidesand interferon-gamma co-stimulated nitric oxide…”
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Synthesis and Cytotoxicity on Human Leukemia Cells of Furonaphthoquinones Isolated from Tabebuia Plants
Published in Chemical & pharmaceutical bulletin (01-06-2013)“…Furonaphthoquinones are promising skeletons for anticancer drug molecules. In particular, methoxylated furonaphthoquinones are characteristic constituents of…”
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13
Modification Structure of Cinnamaldehyde with Primary Amines by Reflux and Sonication Methods in the Presence of Sulfuric Acid as a Catalyst
Published in Science & technology Indonesia (30-06-2024)“…Cinnamon is one of the most valuable natural resources that sustains life and exists freely in nature. Cinnamaldehyde is the primary compound in cinnamon oil…”
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(-)- O -Methylcubebin from Vitex trifolia Enhanced Adipogenesis in 3T3-L1 Cells via the Inhibition of ERK1/2 and p38MAPK Phosphorylation
Published in Molecules (Basel, Switzerland) (24-12-2019)“…In this study, for the purpose of elucidation for antidiabetic components, we isolated and identified compounds that could become lead compounds for the…”
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CoCl2 Decreases EC-SOD Expression through Histone Deacetylation in COS7 Cells
Published in Biological & pharmaceutical bulletin (01-12-2016)“…Extracellular-superoxide dismutase (EC-SOD), one of the SOD isozymes, is negatively regulated under hypoxic conditions, and decreases in its expression may…”
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Synthesis of 3-Selena-1-dethiacephems and Selenazepines via Iodocyclization
Published in Organic letters (07-08-2008)“…A convenient approach to synthesize novel selenium-β-lactams, 3-selena-1-dethiacephems and selenazepines, was accomplished via the regioselective…”
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pH-Triggered Drug Release Controlled by Poly(Styrene Sulfonate) Growth Hollow Mesoporous Silica Nanoparticles
Published in ACS omega (03-03-2020)“…In the current report, hollow mesoporous silica (HMS) nanoparticles were successfully prepared by means of a hard-templating method and further modified with…”
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Phenolic glycosides from young fruits of Citrullus lanatus
Published in Phytochemistry letters (01-12-2020)“…[Display omitted] •Investigation for young fruits of Citrullus lanatus.•Two new phenolic glycosides (citrulluside H and citrulluside T).•Citrulluside H and…”
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In-vitro cytotoxicity of synthesized phthalide-fused indoles and indolines against HL-60 and HepG2 cells
Published in Arabian journal of chemistry (01-02-2020)“…[Display omitted] Phthalide derivatives bearing indole or indoline moieties were successfully synthesized via eco-friendly method and were evaluated for their…”
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Isoselenocyanates: a powerful tool for the synthesis of selenium-containing heterocycles
Published in Molecules (17-03-2007)“…Selenium-containing heterocyclic compounds have been well recognized, not only because of their remarkable reactivities and chemical properties, but also…”
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