Search Results - "Kokeny, Gabor"
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Zymosan Particle-Induced Hemodynamic, Cytokine and Blood Cell Changes in Pigs: An Innate Immune Stimulation Model with Relevance to Cytokine Storm Syndrome and Severe COVID-19
Published in International journal of molecular sciences (06-01-2023)“…Hemodynamic disturbance, a rise in neutrophil-to-lymphocyte ratio (NLR) and release of inflammatory cytokines into blood, is a bad prognostic indicator in…”
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Panel miRNAs are potential diagnostic markers for chronic kidney diseases: a systematic review and meta-analysis
Published in BMC nephrology (13-08-2024)“…Accurate detection of kidney damage is key to preventing renal failure, and identifying biomarkers is essential for this purpose. We aimed to assess the…”
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A Systematic Review and Meta-Analysis of microRNA Profiling Studies in Chronic Kidney Diseases
Published in Non-coding RNA (03-05-2024)“…Chronic kidney disease (CKD) represents an increasing health burden. Evidence suggests the importance of miRNA in diagnosing CKD, yet the reports are…”
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The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus
Published in Cardiovascular diabetology (31-10-2015)“…Diabetes mellitus (DM) leads to the development of diabetic cardiomyopathy, which is associated with altered nitric oxide (NO)--soluble guanylate cyclase…”
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Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation
Published in Scientific reports (27-10-2017)“…While heart transplantation (HTX) is the definitive therapy of heart failure, donor shortage is emerging. Pharmacological activation of soluble guanylate…”
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2949 Diverse effect of STAT3 inhibition on murine primary tubular epithelial cells
Published in Nephrology, dialysis, transplantation (23-05-2024)“…Abstract Background and Aims The incidence of chronic kidney diseases increases worldwide, and kidney fibrosis is the final common pathway regardless of the…”
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Small Interfering RNA Targeting Fas Protects Mice against Renal Ischemia-Reperfusion Injury
Published in Proceedings of the National Academy of Sciences - PNAS (12-10-2004)“…Fas-mediated apoptosis has been suggested to contribute to tubular cell death after renal ischemia-reperfusion injury. Here we investigate whether small…”
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2884 Dose-dependent EGR1 expression in the rat renal medulla after chronic NSAID treatment
Published in Nephrology, dialysis, transplantation (23-05-2024)“…Abstract Background and Aims Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used in clinical medicine. Chronic use of NSAIDs is associated with…”
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5526 COMPLEMENT C3 EXERTS DIRECT PRO-FIBROTIC EFFECTS ON KIDNEY TUBULES
Published in Nephrology, dialysis, transplantation (14-06-2023)“…Abstract Background and Aims Renal complement expression has been observed in both experimental and human kidney diseases. We have previously reported massive…”
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5503 PIOGLITAZONE REVERSES MIR-130A AND MIR-199 DYSREGULATION INDUCED BY TGF-BETA DURING KIDNEY FIBROSIS
Published in Nephrology, dialysis, transplantation (14-06-2023)“…Abstract Background and Aims The peroxisome proliferator-activated receptor-γ (PPARγ) agonists have been shown to dampen TGF-β signaling and suppress miR-130a…”
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MO404: Autophagy and Fibrotic Response is Genetically Determined in Mouse Mesangial Cells
Published in Nephrology, dialysis, transplantation (03-05-2022)“…Abstract BACKGROUND AND AIMS C57Bl6/J (B6) mouse strain is resistant to several experimental models of renal fibrosis. Mesangial cells play an important role…”
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MO612: Relationship of Renal Timp-1, Stat3 and Inflammatory Factors in Diabetes
Published in Nephrology, dialysis, transplantation (03-05-2022)“…Abstract BACKGROUND AND AIMS The balance of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMP) is disrupted in diabetic nephropathy and renal…”
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P0681TIMP-1 DEFICIENCY DAMPENS RENAL GALECTIN-3 RESPONSE IN DIABETES
Published in Nephrology, dialysis, transplantation (01-06-2020)“…Abstract Background and Aims Overexpression of tissue inhibitors of metalloproteases (TIMPs) are a hallmark of renal fibrosis, and elevated TIMP-1 has been…”
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FP345TIMP-1 DEFICIENCY REDUCES TGF-BETA EXPRESSION AND DAMPENS RENAL FIBROSIS AFTER RENAL ABLATION
Published in Nephrology, dialysis, transplantation (01-06-2019)Get full text
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SP270GENETIC SUSCEPTIBILITY TO TGF-BETA INDUCED RENAL FIBROSIS IS ASSOCIATED WITH ALTERED MIR-199 EXPRESSION
Published in Nephrology, dialysis, transplantation (01-05-2018)Get full text
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SP257EARLY RENAL INFLAMMATORY MOLECULE EXPRESSION DIFFERENCES AFTER UNILATERAL URETER OBSTRUCTION IN MICE
Published in Nephrology, dialysis, transplantation (01-05-2018)Get full text
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P0721PPAR-GAMMA ACTIVATION INHIBITS TGF-BETA INDUCED RENAL COMPLEMENT AND GALECTIN-3 EXPRESSION IN VIVO AND IN VITRO
Published in Nephrology, dialysis, transplantation (01-06-2020)“…Abstract Background and Aims Reduced peroxisome proliferator-activated receptor-γ (PPARγ) activity has been observed in chronic kidney disease and fibrosis. We…”
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MP360DELAYED PROGRESSION OF RENAL FIBROSIS IN C57BL6/J MICE IS ASSOCIATED WITH ROBUST MMP ACTIVITY
Published in Nephrology, dialysis, transplantation (01-05-2017)Get full text
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MP097SUSTAINED HYPEROSMOLARITY LEADS TO THE EXPRESSION OF PROFIBROTIC FACTORS IN VIVO
Published in Nephrology, dialysis, transplantation (01-05-2017)Get full text
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