Search Results - "Kokaji, Andy I"
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The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells
Published in Science (American Association for the Advancement of Science) (28-01-2022)“…Human biology is tightly linked to proteins, yet most measurements do not precisely determine alternatively spliced sequences or posttranslational…”
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Virus-induced eosinophil mediator release requires antigen-presenting and CD4+ T cells
Published in Journal of allergy and clinical immunology (01-07-2008)“…Background The most frequent trigger of asthma exacerbation is infection with common airway viruses; however, the precise mechanism regulating such severe…”
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IL-15 Transpresentation Augments CD8+ T Cell Activation and Is Required for Optimal Recall Responses by Central Memory CD8+ T Cells
Published in The Journal of immunology (1950) (01-04-2008)“…Although the adaptive immune system has a remarkable ability to mount rapid recall responses to previously encountered pathogens, the cellular and molecular…”
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4
Evaluating antigen-specific cytotoxic T lymphocyte responses by a novel mouse granzyme B ELISPOT assay
Published in Journal of immunological methods (20-01-2006)“…We have established novel ELISA- and ELISPOT-based assays specific for the detection of a potent cytotoxic mediator, granzyme B (GrB), for the assessment of…”
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Easy 250 EasySep&[trade] Magnet: A Novel Magnetic Platform For Large-Volume CD34+ Hematopoietic Stem and Progenitor Cell Isolation from Leukapheresis Products
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract We have developed a novel magnetic platform for large-volume CD34+ hematopoietic stem and progenitor cell (HPSC) isolation from both mobilized and…”
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EasySep&[trade] T75 Magnet: A Novel Magnetic Platform for Large-Volume Cell Isolation from Whole Blood and Leukapheresis Packs
Published in The Journal of immunology (1950) (01-05-2021)“…Abstract Isolating cells from large volume-samples such as leukapheresis or whole blood bags is a common procedure that precedes many immunological studies…”
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Robust Serum- and Feeder-Free Expansion of Mouse B Cells In Vitro
Published in The Journal of immunology (1950) (01-05-2022)“…Abstract Mouse B cells are used in workflows to discover novel therapeutic antibodies or develop preclinical applications using genetically engineered B cells…”
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A new benchtop system for simple and versatile introduction of macromolecules into human lymphocytes and CD34+ cells by microfluidic squeezing
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract Intracellular delivery of molecules is a key step in biological research that enables the development of new methods of cell and gene-based therapies…”
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Automated Large-Scale T Cell Isolation in a New Closed Cell Separation System
Published in The Journal of immunology (1950) (01-05-2021)“…Abstract Large-scale T cell isolation is commonly performed in a wide range of laboratory settings, including for cell therapy and drug discovery research, as…”
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10
Quick and Easy Isolation of Immune Cells From Large-Volume Samples
Published in The Journal of immunology (1950) (01-05-2022)“…Abstract Large-scale cell isolation is commonly performed in labs and core facilities for cell banking and drug discovery, and as a critical step in cell…”
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Isolation of Tumor-Infiltrating Leukocytes from Mouse Tumors
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Cell-based immunotherapy is being evaluated in various types of cancer and it is one of the most rapidly growing and promising areas of cancer…”
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Isolation of human CD45+ leukocytes from tissues and human tumor xenografts in humanized mice
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract The study of immune cell function in non-lymphoid tissue and tumors promises to elucidate novel strategies to treat immune disorders, infectious…”
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Fast and easy immunomagnetic positive selection of PE- or biotin-conjugated antibody-labelled cells with Releasable Rapidspheres results in highly purified, functional and particle-free cells
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract Immunomagnetic cell isolation is a cost-effective and gentle method of obtaining purified cell populations. However, isolating novel or rare cell…”
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Fast and easy immunomagnetic isolation of untouched human naïve T cells in less than 15 minutes
Published in The Journal of immunology (1950) (01-05-2018)“…Abstract Peripheral blood circulating T cells can be subdivided into either antigen experienced effector and memory T cells or naïve T cells that have not yet…”
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Optimization of human T cell activation and expansion protocols improves efficiency of genetic modification and overall cell yield
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Cancer immunotherapy using CAR T-cells is a rapidly progressing field and manufacturing these cells is a complex process that requires multiple…”
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Rapid Isolation of untouched mouse MDSCs
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that regulate immune responses in cancer, chronic infections and…”
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Isolation of mouse CD45 positive leukocytes from tissues
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Immune cell function is often tissue-specific, therefore isolating cells from their tissue microenvironment is necessary to better understand their…”
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A fast and robust protocol for immunomagnetic isolation of human CD45+ leukocytes from samples with variable start frequencies
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract The study of immune cell function in non-lymphoid tissue and tumors has emerged as an exciting research area, with the promise to provide novel…”
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Releasable RapidSpheres™ enable immunomagnetic purification of highly viable and functional immune cells from complex tissues in less than 30 minutes
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Recent advances in cellular therapy and diagnostics promise dramatic improvements in disease prevention and treatment. This research is driven by…”
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Fast and easy isolation of CD27-positive human memory B cells using EasySep&[trade] Releasable RapidSpheres&[trade]
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract Over the course of a lifetime, memory B cells are key to maintaining antibody-mediated protection from viral and bacterial pathogens and they are one…”
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