Search Results - "Kok Haur Ong"
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1
Endocytic reawakening of motility in jammed epithelia
Published in Nature materials (01-05-2017)“…Dynamics of epithelial monolayers has recently been interpreted in terms of a jamming or rigidity transition. How cells control such phase transitions is,…”
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Journal Article -
2
A Graph-Theoretical Approach for Tracing Filamentary Structures in Neuronal and Retinal Images
Published in IEEE transactions on medical imaging (01-01-2016)“…The aim of this study is about tracing filamentary structures in both neuronal and retinal images. It is often crucial to identify single neurons in neuronal…”
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Journal Article -
3
Quantitative image-based collagen structural features predict the reversibility of hepatitis C virus-induced liver fibrosis post antiviral therapies
Published in Scientific reports (19-04-2023)“…The novel targeted therapeutics for hepatitis C virus (HCV) in last decade solved most of the clinical needs for this disease. However, despite antiviral…”
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4
Geometric constraints alter cell arrangements within curved epithelial tissues
Published in Molecular biology of the cell (01-12-2017)“…Organ and tissue formation are complex three-dimensional processes involving cell division, growth, migration, and rearrangement, all of which occur within…”
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Journal Article -
5
Quantitative stain-free imaging and digital profiling of collagen structure reveal diverse survival of triple negative breast cancer patients
Published in Breast cancer research : BCR (06-05-2020)“…Stromal and collagen biology has a significant impact on tumorigenesis and metastasis. Collagen is a major structural extracellular matrix component in breast…”
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Journal Article -
6
Quantitative 3D analysis of complex single border cell behaviors in coordinated collective cell migration
Published in Nature communications (04-04-2017)“…Understanding the mechanisms of collective cell migration is crucial for cancer metastasis, wound healing and many developmental processes. Imaging a migrating…”
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Journal Article -
7
A comprehensive AI model development framework for consistent Gleason grading
Published in Communications medicine (09-05-2024)“…Background Artificial Intelligence(AI)-based solutions for Gleason grading hold promise for pathologists, while image quality inconsistency, continuous data…”
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8
Automatic white matter lesion segmentation using an adaptive outlier detection method
Published in Magnetic resonance imaging (01-07-2012)“…Abstract White matter (WM) lesions are diffuse WM abnormalities that appear as hyperintense (bright) regions in cranial magnetic resonance imaging (MRI). WM…”
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9
Automatic DNA replication tract measurement to assess replication and repair dynamics at the single-molecule level
Published in Bioinformatics (15-09-2022)“…Abstract Motivation DNA fibre assay has a potential application in genomic medicine, cancer and stem cell research at the single-molecule level. A major…”
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10
OpenSegSPIM: a user-friendly segmentation tool for SPIM data
Published in Bioinformatics (01-07-2016)“…OpenSegSPIM is an open access and user friendly 3D automatic quantitative analysis tool for Single Plane Illumination Microscopy data. The software is designed…”
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11
Single-cell landscape of functionally cured chronic hepatitis B patients reveals activation of innate and altered CD4-CTL-driven adaptive immunity
Published in Journal of hepatology (01-07-2024)“…Hepatitis B surface antigen (HBsAg) loss or functional cure (FC) is considered the optimal therapeutic outcome for patients with chronic hepatitis B (CHB)…”
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Journal Article -
12
Sustained delivery of anti-VEGFs from thermogel depots inhibits angiogenesis without the need for multiple injections
Published in Biomaterials science (01-11-2019)“…Anti-vascular endothelial growth factor (anti-VEGF) proteins are the gold-standard treatment for posterior eye segment proliferative vascular diseases such as…”
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Journal Article -
13
Surgical Transplantation of Human RPE Stem Cell-Derived RPE Monolayers into Non-Human Primates with Immunosuppression
Published in Stem cell reports (09-02-2021)“…Recent trials of retinal pigment epithelium (RPE) transplantation for the treatment of disorders such as age-related macular degeneration have been promising…”
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Journal Article -
14
NeuronCyto II: An automatic and quantitative solution for crossover neural cells in high throughput screening
Published in Cytometry. Part A (01-08-2016)“…Microscopy is a fundamental technology driving new biological discoveries. Today microscopy allows a large number of images to be acquired using, for example,…”
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Journal Article -
15
Endocytic reawakening of motility in jammed epithelia
Published in Nature materials (01-05-2017)“…Dynamics of epithelial monolayers has recently been interpreted in terms of a jamming or rigidity transition. How cells control such phase transitions is,…”
Get full text
Journal Article -
16
Investigation of Data Leakage in Stroke Lesion Detection Through Diffusion Weighted Imaging Using Data Splitting Approaches
Published in 2024 5th International Conference on Artificial Intelligence and Data Sciences (AiDAS) (03-09-2024)“…Ischemic stroke presents a significant global health challenge, often leading to disability and death. Computer-aided diagnosis (CAD) systems utilizing…”
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Conference Proceeding -
17
Gaussian Mixture Model - Expectation Maximization Algorithm for Brain Images
Published in 2021 2nd International Conference on Artificial Intelligence and Data Sciences (AiDAS) (08-09-2021)“…Segmentation of human brain can be performed with the aid of mathematical algorithm as well as computer-based system to assist radiologists and medical related…”
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Conference Proceeding