Search Results - "Kok, Eloise H"
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A postmortem study suggests a revision of the dual-hit hypothesis of Parkinson’s disease
Published in NPJ Parkinson's Disease (30-11-2022)“…The dual-hit hypothesis of Parkinson’s disease (PD) originally postulated that a neurotropic pathogen leads to formation of α-synuclein pathology in the…”
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Alpha-synuclein pathology of olfactory bulbs/peduncles in the Vantaa85+ cohort exhibit two divergent patterns: a population-based study
Published in Acta neuropathologica (01-10-2021)Get full text
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HSV presence in brains of individuals without dementia: the TASTY brain series
Published in Disease models & mechanisms (01-11-2016)“…Herpes simplex virus (HSV) type 1 affects a majority of the population and recent evidence suggests involvement in Alzheimer's disease aetiology. We…”
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Accumulation of Lewy-Related Pathology Starts in Middle Age: The Tampere Sudden Death Study
Published in Annals of neurology (01-05-2024)“…When effective treatments against neurodegenerative diseases become a reality, it will be important to know the age these pathologies begin to develop. We…”
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Beer Drinking Associates with Lower Burden of Amyloid Beta Aggregation in the Brain: Helsinki Sudden Death Series
Published in Alcoholism, clinical and experimental research (01-07-2016)“…Background Controversy surrounds the effect of alcohol consumption on the development of dementia and cognitive impairment. We investigated the association…”
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CLU, CR1 and PICALM genes associate with Alzheimer's-related senile plaques
Published in Alzheimer's research & therapy (05-04-2011)“…APOE is the strongest risk gene for sporadic Alzheimer's disease (AD) so far. Recent genome wide association studies found links for sporadic AD with CLU and…”
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Limbic-predominant age-related TDP-43 encephalopathy in the oldest old: a population-based study
Published in Brain (London, England : 1878) (28-06-2024)“…Population-based cohort studies are essential for understanding the pathological basis of dementia in older populations. Previous studies have shown that…”
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CRP gene variation affects early development of Alzheimer's disease-related plaques
Published in Journal of neuroinflammation (11-08-2011)“…We used the Tampere Autopsy Study (TASTY) series (n = 603, age 0-97 yrs), representing an unselected population outside institutions, to investigate the…”
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