Search Results - "Kojouharova, Mihaela S."

Structural and functional anatomy of the globular domain of complement protein C1q by Kishore, Uday, Ghai, Rohit, Greenhough, Trevor J., Shrive, Annette K., Bonifati, Domenico M., Gadjeva, Mihaela G., Waters, Patrick, Kojouharova, Mihaela S., Chakraborty, Trinad, Agrawal, Alok

“…C1q is the first subcomponent of the classical pathway of the complement system and a major connecting link between innate and acquired immunity. As a…”
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C1q and its growing family by Ghai, Rohit, Waters, Patrick, Roumenina, Lubka T, Gadjeva, Mihaela, Kojouharova, Mihaela S, Reid, Kenneth B.M, Sim, Robert B, Kishore, Uday

“…Abstract C1q is the target recognition protein of the classical complement pathway and a major connecting link between innate and acquired immunity. As a…”
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Interaction of Human C1q with IgG and IgM: Revisited by Gadjeva, Mihaela G., Rouseva, Marieta M., Zlatarova, Alexandra S., Reid, Kenneth B. M., Kishore, Uday, Kojouharova, Mihaela S.

“…The first step of activation of the classical complement pathway involves the binding of the globular C1q domain (gC1q) to the antigen-bound IgG or IgM. To…”
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Interaction of C1q with IgG1, C-reactive Protein and Pentraxin 3:  Mutational Studies Using Recombinant Globular Head Modules of Human C1q A, B, and C Chains by Roumenina, Lubka T, Ruseva, Marieta M, Zlatarova, Alexandra, Ghai, Rohit, Kolev, Martin, Olova, Neli, Gadjeva, Mihaela, Agrawal, Alok, Bottazzi, Barbara, Mantovani, Alberto, Reid, Kenneth B. M, Kishore, Uday, Kojouharova, Mihaela S

“…C1q is the first subcomponent of the classical complement pathway that can interact with a range of biochemically and structurally diverse self and nonself…”
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Modular Organization of the Carboxyl-Terminal, Globular Head Region of Human C1q A, B, and C Chains by Kishore, Uday, Gupta, Sanjeev K, Perdikoulis, Michael V, Kojouharova, Mihaela S, Urban, Britta C, Reid, Kenneth B. M

“…The first step in the activation of the classical complement pathway, by immune complexes, involves the binding of the globular heads of C1q to the Fc regions…”
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Role of Ca2+ in the Electrostatic Stability and the Functional Activity of the Globular Domain of Human C1q by Roumenina, Lubka T, Kantardjiev, Alexandar A, Atanasov, Boris P, Waters, Patrick, Gadjeva, Mihaela, Reid, Kenneth B. M, Mantovani, Alberto, Kishore, Uday, Kojouharova, Mihaela S

“…C1q is the recognition subunit of the classical pathway of the complement system and a major connecting link between classical pathway-driven innate immunity…”
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Existence of Different but Overlapping IgG- and IgM-Binding Sites on the Globular Domain of Human C1q by Zlatarova, Alexandra S, Rouseva, Marieta, Roumenina, Lubka T, Gadjeva, Mihaela, Kolev, Martin, Dobrev, Ivan, Olova, Neli, Ghai, Rohit, Jensenius, Jens Chr, Reid, Kenneth B. M, Kishore, Uday, Kojouharova, Mihaela S

“…C1q is the first subcomponent of the classical complement pathway that binds antigen-bound IgG or IgM and initiates complement activation via association of…”
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Mutational Analyses of the Recombinant Globular Regions of Human C1q A, B, and C Chains Suggest an Essential Role for Arginine and Histidine Residues in the C1q-IgG Interaction by Kojouharova, Mihaela S, Gadjeva, Mihaela G, Tsacheva, Ivanka G, Zlatarova, Aleksandra, Roumenina, Liubka T, Tchorbadjieva, Magdalena I, Atanasov, Boris P, Waters, Patrick, Urban, Britta C, Sim, Robert B, Reid, Kenneth B. M, Kishore, Uday

“…The first step in the activation of the classical complement pathway by immune complexes involves the binding of the globular domain (gC1q) of C1q to the Fc…”
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Localization of ligand-binding sites on human C1q globular head region using recombinant globular head fragments and single-chain antibodies by Kojouharova, Mihaela S., Tsacheva, Ivanka G., Tchorbadjieva, Magdalena I., Reid, Kenneth B.M., Kishore, Uday

“…As a charge pattern recognition molecule, human C1q can bind a range of immunoglobulin and non-immunoglobulin ligands via its carboxy-terminal globular domain…”
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Recent Progress in the Understanding of the Structure- Function Relationships of the Globular Head Regions of C1q by Kishore, Uday, Kojouharova, Mihaela S., Reid, Kenneth B.M.

“…The first step in the activation of the classical pathway of complement cascade by immune complexes involves the binding of the C-terminal globular head…”
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Differential Binding of IgG and of a HIV gp41 Peptide by the B Chain and A Chain Globular Head Sequences of C1q, Respectively by Kojouharova, Mihaela S, Panchev, Ivelin D, Tchorbadjieva, Magdalena I, Reid, Kenneth B. M, Hoppe, Hans-Jurgen

“…Two individual globular head regions (ghA and ghB) of the heterotrimeric C1q molecule (containing A, B, and C chains) were expressed in a bacterial expression…”
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Role of Ca 2+ in the Electrostatic Stability and the Functional Activity of the Globular Domain of Human C1q by Roumenina, Lubka T., Kantardjiev, Alexandar A., Atanasov, Boris P., Waters, Patrick, Gadjeva, Mihaela, Reid, Kenneth B. M., Mantovani, Alberto, Kishore, Uday, Kojouharova, Mihaela S.

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Erratum to “Structural and functional anatomy of the globular domain of complement protein C1q” [Immunol. Lett. 95 (2) (2004) 113–128] by Kishore, Uday, Ghai, Rohit, Greenhough, Trevor J., Shrive, Annette K., Bonifati, Domenico M., Gadjeva, Mihaela G., Waters, Patrick, Kojouharova, Mihaela S., Chakraborty, Trinad, Agrawal, Alok

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