Search Results - "Koji Kuboki"

Influence of Fatty Liver on Plasma Small, Dense LDL- Cholesterol in Subjects with and without Metabolic Syndrome by Sugino, Ikumi, Kuboki, Koji, Matsumoto, Tomoko, Murakami, Eiichi, Nishimura, Chiaki, Yoshino, Gen

“…Aim: Small, dense low density lipoprotein (sLDL) is known as an atherogenic lipoprotein and is often associated with metabolic syndrome (MS). A high frequency…”
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Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways by Igarashi, Masahiko, Wakasaki, Hisao, Takahara, Noriko, Ishii, Hidehiro, Jiang, Zhen-Y, Yamauchi, Teruaki, Kuboki, Koji, Meier, Matthias, Rhodes, Christopher J., King, George L.

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Small,dense LDL and High-Sensitivity C-Reactive Protein (hs-CRP) in Metabolic Syndrome with Type 2 Diabetes Mellitus by Nakano, Saburo, Kuboki, Koji, Matsumoto, Tomoko, Nishimura, Chiaki, Yoshino, Gen

“…Aim: To clarify the clinical significance of small,dense LDL (sLDL) in the metabolic syndrome associated with type 2 diabetes. Methods: One hundred and ten…”
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A Case of Severe Acute Necrotizing Pancreatitis after Administration of Sitagliptin by Sue, Mariko, Yoshihara, Aya, Kuboki, Koji, Hiroi, Naoki, Yoshino, Gen

“…A 55-year-old Japanese man with a 3-year history of type 2 diabetes mellitus was admitted to our hospital for upper abdominal pain. Control of diabetes…”
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Erratum: Influence of Fatty Liver on Plasma Small, Dense LDL- Cholesterol in Subjects with and without Metabolic Syndrome[Journal of Atherosclerosis and Thrombosis 1-7] by Sugino, Ikumi, Kuboki, Koji, Matsumoto, Tomoko, Murakami, Eiichi, Nishimura, Chiaki, Yoshino, Gen

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Thyroid storm associated with Graves' disease covered by diabetic ketoacidosis: A case report by Osada, Erika, Hiroi, Naoki, Sue, Mariko, Masai, Natsumi, Iga, Ryo, Shigemitsu, Rika, Oka, Reiko, Miyagi, Masahiko, Iso, Kaoru, Kuboki, Koji, Yoshino, Gen

“…Thyroid storm is a condition in which multiple organ dysfunction results from failure of the compensatory mechanisms of the body owing to excessive thyroid…”
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Long-term effect of epalrestat, an aldose reductase inhibitor, on the development of incipient diabetic nephropathy in Type 2 diabetic patients by Iso, Kaoru, Tada, Hisaya, Kuboki, Koji, Inokuchi, Toshiki

“…The aim of the present study was to elucidate the long-term effect of epalrestat, an aldose reductase inhibitor (ARI), on renal function in patients with type…”
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Role of protein kinase C-angiotensin II pathway for extracellular matrix production in cultured human mesangial cells exposed to high glucose levels by Ikehara, Kayoko, Tada, Hisaya, Kuboki, Koji, Inokuchi, Toshiki

“…The intrarenal renin-angiotensin system has been implicated in the pathogenesis of diabetic nephropathy. This study investigates the mechanisms for…”
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High glucose levels enhance TGF-β1–thrombospondin-1 pathway in cultured human mesangial cells via mechanisms dependent on glucose-induced PKC activation by Tada, Hisaya, Kuboki, Koji, Nomura, Kayoko, Inokuchi, Toshiki

“…We have previously demonstrated that thrombospondin-1 (TSP-1) promotes activation of latent TGF-β1 in cultured human mesangial cells (MCs) [Nephron 79 (1998)…”
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Effects of Valsartan on Inflammatory and Oxidative Stress Markers in Hypertensive, Hyperglycemic Patients: An Open-Label, Prospective Study by Kuboki, Koji, MD, PhD, Iso, Kaoru, MD, PhD, Murakami, Eiichi, BS, Abe, Seiko, BS, Araki, Emi, BS, Ueshiba, Hajime, MD, PhD, Yoshino, Gen, MD, PhD

“…Abstract Background: Diabetes mellitus and hypertension are aggravated by activation of the renin-angiotensin system caused by increased oxygen stress and…”
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P4-7-2 TSH-receptor autoimmunity and ophthalmopathy after radiolodine therapy by Kumiko Tsuboi, Natsuko Watanabe, Mayumi Ishikawa, Rena Yuasa, Ryo Iga, Natsumi Masai, Mariko Sue, Aya Yoshihara, Masahiko Miyagi, Kaoru Iso, Takamasa Ichijo, Naoki Hiroi, Koji Kuboki, Hajime Ueshiba, Gen Yoshino

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Role of growth hormone signaling pathways in the development of atherosclerosis by Ishikawa, Mayumi, Toyomura, Junko, Yagi, Takashi, Kuboki, Koji, Morita, Toshisuke, Sugihara, Hitoshi, Hirose, Takahisa, Minami, Shiro, Yoshino, Gen

“…The direct actions of growth hormone (GH) in the development of atherosclerosis are unclear. The goal of this study was to characterize GH-induced changes in…”
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Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : A specific vascular action of insulin by KUBOKI, K, JIANG, Z. Y, TAKAHARA, N, SUNGWOOHA, IGARASHI, M, YAMAUCHI, T, FEENER, E. P, HERBERT, T. P, RHODES, C. J, KING, G. L

“…The vasodilatory effect of insulin can be acute or increase with time from 1 to 7 hours, suggesting that insulin may enhance the expression of endothelial…”
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Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways by Igarashi, M, Wakasaki, H, Takahara, N, Ishii, H, Jiang, Z Y, Yamauchi, T, Kuboki, K, Meier, M, Rhodes, C J, King, G L

“…Hyperglycemia can cause vascular dysfunctions by multiple factors including hyperosmolarity, oxidant formation, and protein kinase C (PKC) activation. We have…”
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Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats by Koya, D, Jirousek, M R, Lin, Y W, Ishii, H, Kuboki, K, King, G L

“…Induction of protein kinase C (PKC) pathway in the vascular tissues by hyperglycemia has been associated with many of the cellular changes observed in the…”
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A ase of evere Acute ecrotizing ancreatitis after Administration of itagliptin by Mariko Sue, Aya Yoshihara, Koji Kuboki, Naoki Hiroi, Gen Yoshino

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Graves' disease with intractable diarrhea, chylous ascites, and chylothorax: a case report by Hiroi, Naoki, Sakamoto, Yasunari, Urita, Yoshihisa, Higa, Mariko, Kuboki, Koji, Yoshino, Gen

“…A 50-year-old woman was admitted to our hospital because of severe diarrhea, irritableness, and severe pitting edema of the legs. The patient had been well…”
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A Case of Severe Acute Necrotizing Pancreatitis after Administration of Sitagliptin by Mariko Sue, Aya Yoshihara, Koji Kuboki, Naoki Hiroi, Gen Yoshino

“…A 55-year-old Japanese man with a 3-year history of type 2 diabetes mellitus was admitted to our hospital for upper abdominal pain. Control of diabetes…”
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Diabetic ketoacidosis associated with adrenocorticotropic hormone-producing pituitary adenoma by Sugino, Ikumi, Hiroi, Naoki, Yoshihara, Aya, Sue, Mariko, Tojo, Yasushi, Iso, Kaoru, Kuboki, Koji, Tanioka, Daisuke, Abe, Takumi, Yoshino, Gen

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Transforming growth factor-beta-1 latency-associated peptide and soluble betaglycan prevent a glucose-induced increase in fibronectin production in cultured human mesangial cells by Nomura, Kayoko, Tada, Hisaya, Kuboki, Koji, Inokuchi, Toshiki

“…This study was performed to investigate the effects of transforming growth factor-beta1 (TGF-beta1) latency-associated peptide (LAP) and betaglycan on…”
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