Search Results - "Kojda, G"

Molecular mechanisms of vascular adaptations to exercise. Physical activity as an effective antioxidant therapy? by KOJDA, Georg, HAMBRECHT, Rainer

“…A lack of exercise training and/or regular physical activity is a known risk factor for cardiovascular disease. Exercise training induces marked vascular…”
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Nonallergic angioedema: role of bradykinin by Bas, M, Adams, V, Suvorava, T, Niehues, T, Hoffmann, T.K, Kojda, G

“…Angioedema is an underestimated clinical problem. Many cases are nonallergic reactions, e.g. bradykinin-induced angioedema caused by genetic defects and…”
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Angioedema induced by cardiovascular drugs: new players join old friends by Bas, M., Greve, J., Strassen, U., Khosravani, F., Hoffmann, T. K., Kojda, G.

“…During the last years, two new cardiovascular drug classes, namely inhibitors of DPP IV or neprilysin, have been developed. In both cases, there is clinical…”
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New topics in bradykinin research by Maurer, M., Bader, M., Bas, M., Bossi, F., Cicardi, M., Cugno, M., Howarth, P., Kaplan, A., Kojda, G., Leeb‐Lundberg, F., Lötvall, J., Magerl, M.

“…To cite this article: Maurer M, Bader M, Bas M, Bossi F, Cicardi M, Cugno M, Howarth P, Kaplan A, Kojda G, Leeb‐Lundberg F, Lötvall J, Magerl M. New topics in…”
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Activation of the aryl hydrocarbon receptor by clozapine induces preadipocyte differentiation and contributes to endothelial dysfunction by Fehsel, K, Schwanke, K, Kappel, BA, Fahimi, E, Meisenzahl-Lechner, E, Esser, C, Hemmrich, K, Haarmann-Stemmann, T, Kojda, G, Lange-Asschenfeldt, C

“…Background: The superior therapeutic benefit of clozapine is often associated with metabolic disruptions as obesity, insulin resistance, tachycardia, higher…”
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Stability of murine bradykinin type 2 receptor despite treatment with NO, bradykinin, icatibant, or C1‐INH by Khosravani, F., Suvorava, T., Dao, V. T.‐V., Brockmann, N., Kocgirli, O., Herbst, F. F., Valcaccia, S., Kassack, M. U., Bas, M., Kojda, G.

“…Background Little is known about factors which trigger and/or contribute to hereditary angioedema or ACE‐inhibitor‐mediated angioedema including variations in…”
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Increased C‐reactive protein in ACE‐inhibitor‐induced angioedema by Bas, M., Hoffmann, T. K., Bier, H., Kojda, G.

“…Aims This study was designed to identify new factors which may contribute to angiotensin‐converting‐enzyme‐inhibitor (ACEI)‐induced angioedema. Methods In a…”
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Bradycardic effect of endothelial-specific bradykinin type-II receptors overexpression in mice: impact on blood pressure by Metry, S, Suvorava, T, Kojda, G

“…Abstract Background/Introduction Polymorphisms of the gene encoding for the bradykinin type-II receptors (B2R) has been shown to decrease the expression of B2R…”
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Effect of oral organic nitrates on expression and activity of vascular soluble guanylyl cyclase by Oppermann, M, Dao, V T‐V, Suvorava, T, Bas, M, Kojda, G

“…Background and purpose: The regulation of vascular soluble guanylyl cyclase (sGC) expression by nitric oxide (NO) is still under discussion. In vitro, NO has…”
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Organic nitrates in cardiovascular disease by Bode-Böger, S M, Kojda, G

“…Therapeutic activation of the vascular NO/cGMP pathway is induced by a variety of stimuli/mediators including physical activity, supplementation with the…”
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Increased cardiac endothelial nitric oxide synthase expression in patients taking angiotensin-converting enzyme inhibitor therapy by Morawietz, H., Rohrbach, S., Rueckschloss, U., Schellenberger, E., Hakim, K., Zerkowski, H.-R., Kojda, G., Darmer, D., Holtz, J.

“…Background  The efficacy of angiotensin‐converting enzyme (ACE) inhibitors has been demonstrated in large clinical trials, but knowledge of the underlying…”
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ACE-inhibitor induced angioedema by Bas, M, Hoffmann, T K, Kojda, G, Bier, H

“…ACE-inhibitor induced angioedema is a non-allergic drug-related side effect. Inhibited bradykinin degradation leads to an unphysiological enhanced bradykinin…”
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Novel pharmacotherapy of acute hereditary angioedema with bradykinin B2‐receptor antagonist icatibant by Bas, M., Bier, H., Greve, J., Kojda, G., Hoffmann, T. K.

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Impaired vasodilator response to organic nitrates in isolated basilar arteries by Martens, Dorothee, Kojda, Georg

“…The differential responsiveness of various sections and regions in the vascular system to the vasodilator activity of organic nitrates is important for the…”
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P4488Bradykinin induced skin edema in mice is dependent on cyclooxygenase activity by Bisha, M., Gholamreza-Fahimi, E., Dao Vu, T.V., Kojda, G.

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P4487Bradykinin receptor type two mediated dermal extravasation in mice is potentiated by moexipril by Bisha, M., Gholamreza-Fahimi, E., Dao Vu, T.V., Kojda, G.

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Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure by Kojda, G, Harrison, D

“…There is a growing body of evidence suggesting that numerous pathological conditions are associated with increased vascular production of reactive oxygen…”
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The effect of high-dose pentaerythritol tetranitrate on the development of nitrate tolerance in rabbits by Müllenheim, J, Müller, S, Laber, U, Thämer, V, Meyer, W, Bassenge, E, Fink, B, Kojda, G

“…Experimental studies with therapeutic doses of pentaerythritol tetranitrate (PETN) have shown unexpected actions such as a lack of nitrate tolerance and…”
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Durch ACE-Hemmer induziertes Angioödem des Kopf-Hals-Bereichs: Eine Frage der Zeit? by BAS, M, KOJDA, G, BIER, H, HOFFMANN, T. K

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Vasoprotection by nitric oxide: mechanisms and therapeutic potential by GEWALTIG, Michael T, KOJDA, Georg

“…Endothelial production of nitric oxide (nitrogen monoxide, NO) has become a major research area in vascular biology. Some of the most important effects that NO…”
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