Search Results - "Koiri, Raj Kumar"

Protective and therapeutic effects of sildenafil and tadalafil on aflatoxin B1-induced hepatocellular carcinoma by Chhonker, Saurabh K., Rawat, Divya, Koiri, Raj Kumar

“…Hepatocellular carcinoma (HCC) has been classified as one of the most common forms of liver cancer occurring worldwide, and risk factors include hepatitis B &…”
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Lactate as a signaling molecule: Journey from dead end product of glycolysis to tumor survival by Rawat, Divya, Chhonker, Saurabh Kumar, Naik, Rayees Ahmad, Mehrotra, Aditi, Trigun, Surendra Kumar, Koiri, Raj Kumar

“…Global metabolism of cancers exhibits a peculiar phenotype that is lactate acidosis (high lactate with acidic pH) in tumor microenvironment. Why tumor…”
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An overview of the toxic effect of potential human carcinogen Microcystin-LR on testis by Lone, Yaqoob, Koiri, Raj Kumar, Bhide, Mangla

“…The worldwide occurrence of cyanobacterial blooms due to water eutrophication evokes extreme concerns. These blooms produce cyanotoxins which are hazardous to…”
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Microcystin-LR Induced Immunotoxicity in Mammals by Lone, Yaqoob, Koiri, Raj Kumar, Bhide, Mangla

“…Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Exposure to microcystins is a global health problem because of…”
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Ameliorative effect of piracetam on emamectin benzoate induced perturbations in the activity of lactate dehydrogenase in murine system by Naik, Rayees Ahmad, Rawat, Divya, Ahi, Janak Dulari, Koiri, Raj Kumar

“…•Emamectin benzoate induced toxicity increased the level of lactate, activity of LDH and its isozymes in different organs of rats.•Piracetam ameliorates…”
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Metal Cu(II) and Zn(II) bipyridyls as inhibitors of lactate dehydrogenase by Koiri, Raj Kumar, Trigun, Surendra Kumar, Dubey, Santosh Kumar, Singh, Santosh, Mishra, Lallan

“…Metal complex-protein interaction is an evolving concept for determining cellular targets of metallodrugs. Lacatate dehydrogenase (LDH) is critically…”
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Investigation of nanoparticles present in biochemic tissue salt Kalium phosphoricum in different potencies by Dash, Debabrata, Koiri, Raj Kumar

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Amelioratory effect of coenzyme Q10 on potential human carcinogen Microcystin-LR induced toxicity in mice by Lone, Yaqoob, Bhide, Mangla, Koiri, Raj Kumar

“…Microcystins are a group of cyclic heptapeptide toxins produced by cyanobacteria. More than 100 microcystin analogues have been detected, among which…”
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Liver lobes and cirrhosis: Diagnostic insights from lobar ratios by Pandey, Kriti, Dash, Debabrata, Koiri, Raj Kumar

“…Liver cirrhosis is the formation of abnormal nodular structure and fibrosis. Globally it accounts for 4 ​% of all deaths. Alcohol, viral hepatitis, and…”
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Repurposing PDE5 inhibitor tadalafil and sildenafil as anticancer agent against hepatocellular carcinoma via targeting key events of glucose metabolism and multidrug resistance by Chhonker, Saurabh Kumar, Rawat, Divya, Koiri, Raj Kumar

“…Hepatocellular carcinoma (HCC) has emerged as one of the most common and lethal cancers worldwide and is caused due to contamination of diets with aflatoxin B1…”
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Modulation of antioxidant enzymes, SIRT1 and NF‐κB by resveratrol and nicotinamide in alcohol‐aflatoxin B1‐induced hepatocellular carcinoma by Rawat, Divya, Chhonker, Saurabh Kumar, Naik, Rayees Ahmad, Koiri, Raj Kumar

“…Hepatocellular carcinoma (HCC) is the fifth most commonly diagnosed cancer worldwide and is associated with poor prognosis. The current study aimed to assess…”
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SIRT1‐mediated amelioration of oxidative stress in kidney of alcohol‐aflatoxin‐B1‐induced hepatocellular carcinoma by resveratrol is catalase dependent and GPx independent by Rawat, Divya, Shrivastava, Somi, Naik, Rayees Ahmad, Chhonker, Saurabh Kumar, Koiri, Raj Kumar

“…Hepatocellular carcinoma (HCC) is a type of primary liver cancer and dietary exposure to aflatoxins is a major risk factor of HCC. The current study aimed to…”
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Activation of p53 mediated glycolytic inhibition-oxidative stress-apoptosis pathway in Dalton's lymphoma by a ruthenium (II)-complex containing 4-carboxy N-ethylbenzamide by Koiri, Raj Kumar, Trigun, Surendra Kumar, Mishra, Lallan

“…There is a general agreement that most of the cancer cells switch over to aerobic glycolysis (Warburg effect) and upregulate antioxidant enzymes to prevent…”
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Microcystin-leucine arginine (MC-LR) induces bone loss and impairs bone micro-architecture by modulating host immunity in mice: Implications for bone health by Dar, Hamid Y., Lone, Yaqoob, Koiri, Raj Kumar, Mishra, Pradyumna K., Srivastava, Rupesh K.

“…Osteoporosis or enhanced bone loss is one of the most commonly occurring bone conditions in the world, responsible for higher incidence of fractures leading to…”
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Role of cyanotoxins in the development and promotion of cancer by Rajput, Siddharth, Jain, Shruti, Dash, Debabrata, Gupta, Nidhi, Rajpoot, Roshni, Upadhyaya, Chandrama Prakash, Khan, Mohammed Latif, Koiri, Raj Kumar

“…Cyanotoxins are primarily produced by different species of cyanobacteria, also known as blue-green algae, and have appeared to be environmental poisons that…”
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Targetting cancer with Ru(III/II)-phosphodiesterase inhibitor adducts: A novel approach in the treatment of cancer by Koiri, Raj Kumar, Mehrotra, Aditi, Trigun, Surendra Kumar

“…Abstract Lack of specificity and normal tissue toxicity are the two major limitations faced with most of the anticancer agents in current use. Due to effective…”
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Structural characterization and cytotoxicity studies of ruthenium(II)–dmso–chloro complexes of chalcone and flavone derivatives by Prajapati, Rishikesh, Dubey, Santosh Kumar, Gaur, Ruchi, Koiri, Raj Kumar, Maurya, Brajesh Kumar, Trigun, Surendra Kumar, Mishra, Lallan

“…Biologically relevant chalcone and flavone derivatives are complexed with cis-[RuCl 2(dmso) 4] giving two complexes of the general formula fac-[RuCl(S-dmso)…”
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