Search Results - "Koinuma, Takahiro"

Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson’s disease by Saiki, Shinji, Hatano, Taku, Fujimaki, Motoki, Ishikawa, Kei-Ichi, Mori, Akio, Oji, Yutaka, Okuzumi, Ayami, Fukuhara, Takeshi, Koinuma, Takahiro, Imamichi, Yoko, Nagumo, Miho, Furuya, Norihiko, Nojiri, Shuko, Amo, Taku, Yamashiro, Kazuo, Hattori, Nobutaka

“…Increasing evidence shows that metabolic abnormalities in body fluids are distinguishing features of the pathophysiology of Parkinson’s disease. However, a…”
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Hyperostosis frontalis interna in a patient with Alzheimer's disease by Nagai, Yasuhito, Akiba, Chihiro, Hagiwara, Mikiko, Orimo, Narihiro, Koinuma, Takahiro, Shibata, Nobuto

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Metabolomics‐based identification of metabolic alterations in PARK2 by Okuzumi, Ayami, Hatano, Taku, Ueno, Shin‐Ichi, Ogawa, Takashi, Saiki, Shinji, Mori, Akio, Koinuma, Takahiro, Oji, Yutaka, Ishikawa, Kei‐Ichi, Fujimaki, Motoki, Sato, Shigeto, Ramamoorthy, Sivapriya, Mohney, Robert P., Hattori, Nobutaka

“…Objective Parkin is the causative gene for autosomal recessive familial Parkinson's disease (PD), although it remains unclear how parkin dysfunction is…”
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Diffusion MRI Captures White Matter Microstructure Alterations in PRKN Disease by Koinuma, Takahiro, Hatano, Taku, Kamagata, Koji, Andica, Christina, Mori, Akio, Ogawa, Takashi, Takeshige-Amano, Haruka, Uchida, Wataru, Saiki, Shinji, Okuzumi, Ayami, Ueno, Shin-Ichi, Oji, Yutaka, Saito, Yuya, Hori, Masaaki, Aoki, Shigeki, Hattori, Nobutaka

“…Although pathological studies usually indicate pure dopaminergic neuronal degeneration in patients with parkin (PRKN) mutations, there is no evidence to date…”
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Nonmercaptalbumin as an oxidative stress marker in Parkinson’s and PARK2 disease by Ueno, Shin‐Ichi, Hatano, Taku, Okuzumi, Ayami, Saiki, Shinji, Oji, Yutaka, Mori, Akio, Koinuma, Takahiro, Fujimaki, Motoki, Takeshige‐Amano, Haruka, Kondo, Akihide, Yoshikawa, Naoyuki, Nojiri, Takahiro, Kurano, Makoto, Yasukawa, Keiko, Yatomi, Yutaka, Ikeda, Hitoshi, Hattori, Nobutaka

“…Objective To investigate the oxidized albumin ratio, which is the redox ratio of human nonmercaptalbumin (HNA) to serum albumin (%HNA), as a biomarker in…”
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Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy by Mori, Akio, Ishikawa, Kei-Ichi, Saiki, Shinji, Hatano, Taku, Oji, Yutaka, Okuzumi, Ayami, Fujimaki, Motoki, Koinuma, Takahiro, Ueno, Shin-Ichi, Imamichi, Yoko, Hattori, Nobutaka

“…Radiological biomarkers have been reported for multiple system atrophy and progressive supranuclear palsy, but serum/plasma biomarkers for each disorder have…”
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Low Dose of Clonazepam Is Effective in the Treatment of Painless Legs and Moving Toes Syndrome: A Case Report by Kawajiri, Sumihiro, Noda, Kazuyuki, Ikeda, Aya, Koinuma, Takahiro, Tomizawa, Yuji, Hattori, Nobutaka, Okuma, Yasuyuki

“…Introduction: Painless legs and moving toes syndrome (PoLMT) is a rare movement disorder characterized by flexion, extension, abduction, adduction, and torsion…”
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Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling by Mori, Akio, Hatano, Taku, Inoshita, Tsuyoshi, Shiba-Fukushima, Kahori, Koinuma, Takahiro, Meng, Hongrui, Kubo, Shin-ichiro, Spratt, Spencer, Cui, Changxu, Yamashita, Chikara, Miki, Yoshimi, Yamamoto, Kei, Hirabayashi, Tetsuya, Murakami, Makoto, Takahashi, Yoshikazu, Shindou, Hideo, Nonaka, Takashi, Hasegawa, Masato, Okuzumi, Ayami, Imai, Yuzuru, Hattori, Nobutaka

“…Mutations in the iPLA2-VIA/PLA2G6 gene are responsible for PARK14-linked Parkinson’s disease (PD) with α-synucleinopathy. However, it is unclear how iPLA2-VIA…”
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Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease by Fujimaki, Motoki, Saiki, Shinji, Li, Yuanzhe, Kaga, Naoko, Taka, Hikari, Hatano, Taku, Ishikawa, Kei-Ichi, Oji, Yutaka, Mori, Akio, Okuzumi, Ayami, Koinuma, Takahiro, Ueno, Shin-Ichi, Imamichi, Yoko, Ueno, Takashi, Miura, Yoshiki, Funayama, Manabu, Hattori, Nobutaka

“…OBJECTIVETo investigate the kinetics and metabolism of caffeine in serum from patients with Parkinson disease (PD) and controls using liquid…”
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Good's syndrome with opportunistic infection of the central nervous system: a case report by Ueno, Shinichi, Sekimoto-Tsuboi, Satoko, Ishiguro, Yuta, Koinuma, Takahiro, Eguchi, Hiroto, Machida, Yutaka, Hattori, Nobutaka, Miwa, Hideto

“…Immunodeficiency with a thymoma (Good's syndrome) is a rare condition occurring in patients with adult-onset hypogammaglobulinemia that is progressive after…”
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Low dose of clonazepam is effective in the treatment of painless legs and moving toes syndrome: a case report by Kawajiri, Sumihiro, Noda, Kazuyuki, Ikeda, Aya, Koinuma, Takahiro, Tomizawa, Yuji, Hattori, Nobutaka, Okuma, Yasuyuki

“…INTRODUCTIONPainless legs and moving toes syndrome (PoLMT) is a rare movement disorder characterized by flexion, extension, abduction, adduction, and torsion…”
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