Search Results - "Koikov, L.N"

Sub-nanomolar hMC1R agonists by end-capping of the melanocortin tetrapeptide His-D-Phe-Arg-Trp-NH2 by KOIKOV, L. N, EBETINO, F. H, SOLINSKY, M. G, CROSS-DOERSEN, D, KNITTEL, J. J

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Analogs of sub-nanomolar hMC1R agonist LK-184 [Ph(CH 2) 3CO-His- d-Phe-Arg-Trp-NH 2]. An additional binding site within the human melanocortin receptor 1? by Koikov, L.N, Ebetino, F.H, Solinsky, M.G, Cross-Doersen, D, Knittel, J.J

“…Of the 29 analogs of LK-184 ( 1) tested at the human MC1, MC3, and MC4 receptors (R), only LK-312 ( 3), partially mimicking the π-system of 1, had an EC 50 of…”
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End-capping of the modified melanocortin tetrapeptide (p-Cl)Phe-D-Phe-Arg-Trp-NH2 as a route to hMC4R agonists by KOIKOV, L. N, EBETINO, F. H, HAYES, J. C, CROSS-DOERSEN, D, KNITTEL, J. J

“…Of the 42 R'-X-(p-Cl)Phe-D-Phe-Arg-Trp-NH(2) (X=CO, SO(2), PO, PS) tested at the human (h)MC1, hMC3, and hMC4 receptors (R), the most potent MC4R agonists…”
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End-capping of the modified melanocortin tetrapeptide ( p-Cl)Phe- D-Phe-Arg-Trp-NH 2 as a route to hMC4R agonists by Koikov, L.N., Ebetino, F.H., Hayes, J.C., Cross-Doersen, D., Knittel, J.J.

“…Of the 42 R′-X-( p-Cl)Phe- D-Phe-Arg-Trp-NH 2 (X = CO, SO 2, PO, PS) tested on the human (h)MC1, hMC3, and hMC4 receptors (R), the most potent MC4R agonists…”
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Sub-Nanomolar hMC1R Agonists by End-Capping of the Melanocortin Tetrapeptide His- d-Phe-Arg-Trp-NH 2 by Koikov, L.N, Ebetino, F.H, Solinsky, M.G, Cross-Doersen, D, Knittel, J.J

“…Twenty three derivatives of the core fragment His 6- d-Phe 7-Arg 8-Trp 9-NH 2 end-capped with carboxylic and sulfonic acids were synthesized and evaluated at…”
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(He 1) photoelectron spectra of vinyl- and (1-dimethylaminovinyl)pyridines by Baidin, V. N., Koikov, L. N., Terent'ev, P. B., Gloriozov, I. P.

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Nicotinic antagonists (piperidines and quinuclidines) reduce the susceptibility of early sea urchin embryos to agents evoking calcium shock by Buznikov, G.A., Koikov, L.N., Shmukler, Yu.B., Whitaker, M.J.

“…1. 1. Some nicotinic antagonists (piperidine and quinuclidine derivatives and bis-quaternary compounds) protect early embryos of the sea urchin Lytechinus…”
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