Search Results - "Koike, Yuko"
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MASSpy: Building, simulating, and visualizing dynamic biological models in Python using mass action kinetics
Published in PLoS computational biology (28-01-2021)“…Mathematical models of metabolic networks utilize simulation to study system-level mechanisms and functions. Various approaches have been used to model the…”
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Fractionation of radiocesium in soil, sediments, and aquatic organisms in Lake Onuma of Mt. Akagi, Gunma Prefecture using sequential extraction
Published in The Science of the total environment (01-01-2017)“…The Fukushima Daiichi Nuclear Power Plant (FDNPP) accident has resulted in the contamination of the environment in Gunma Prefecture with radioisotope cesium…”
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An Automated Robotic Interface for Assays: Facilitating Machine Learning in Drug Discovery by the Automation of Physicochemical Property Assays
Published in ACS omega (11-06-2024)“…Measuring the physicochemical properties of molecules is an iterative but integral process in the drug development process. A strategy to overcome the…”
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Apoptosis in Human Leukemic Cells Induced by Lactoferricin, a Bovine Milk Protein-Derived Peptide: Involvement of Reactive Oxygen Species
Published in Biochemical and biophysical research communications (28-08-1997)“…We examined the activity of bovine lactoferricin (Lfcin-B), a peptide derived from a bovine milk protein lactoferrin (LF-B), to induce apoptosis in THP-1 human…”
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Design and Synthesis of the Potent, Orally Available, Brain-Penetrable Arylpyrazole Class of Neuropeptide Y5 Receptor Antagonists
Published in Journal of medicinal chemistry (27-02-2003)“…Novel arylpyrazole derivatives were synthesized and evaluated as neuropeptide Y (NPY) Y5 receptor antagonists. Compound (−)-7, which features a novel chiral…”
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Tau protein is a potential biological marker for normal pressure hydrocephalus
Published in Psychiatry and clinical neurosciences (01-04-2000)“…A biological marker for normal pressure hydrocephalus (NPH) is beneficial for evaluation of its severity and of indications for shunt operation. Tau protein…”
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Enhancing activity of mycobacterial cell-derived adjuvants on immunogenicity of recombinant human hepatitis B virus vaccine
Published in Vaccine (01-12-1998)“…In a previous study, we demonstrated that a lipophilic derivative of muramyl dipeptide [MDP-Lys(L18)] augmented antibody response to recombinant human…”
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Development of a genetic system in chitinase-producing Streptomyces and the application of an allosamidin-insensitive chitinase gene to homologous overexpression
Published in Molecular biotechnology (01-03-2004)“…A transformation system for Streptomyces sp. AJ9463 strain (allosamidin producer) was successfully developed using protoplasts and a PEG-mediated method. To…”
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The acquisition of Japanese motion verbs: Lexicalization types and the interaction between verbs and particles
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Dissertation -
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The acquisition of Japanese motion verbs: Lexicalization types and the interaction between verbs and particles
Published 01-01-2002“…Japanese motion verbs display semantically-conditioned structural patterns, which are observed in various verb-particle compatibility constraints. Such…”
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Dissertation -
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Inhibitory effect of trehalose dimycolate (TDM) and its stereoisometric derivatives, trehalose dicorynomycolates (TDCMs), with low toxicity on lung metastasis of tumour cells in mice
Published in Vaccine (17-03-1999)“…We examined the effect of semisynthetic trehalose-6,6′-dimycolate (TDM) and its synthetic stereoisomeric derivatives (trehalose 6,6′-dicorynomycolates; TDCMs)…”
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Adjuvant activity of muramyl dipeptide derivatives to enhance immunogenicity of a hantavirus-inactivated vaccine
Published in Vaccine (01-01-1998)“…The adjuvant effect of two lipophilic derivatives of muramyl dipeptide (MDP), B30-MDP and MDP-Lys(L18), on the ability of an inactivated vaccine of B-1 virus…”
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DETERMINATION METHOD AND STABILITY OF CEFPIROME SULFATE IN BIOLOGICAL SAMPLES
Published in CHEMOTHERAPY (1991)“…We established microbiological assay (bioassay) and HPLC methods for determinat on of cefpirome sulfate (CPR) in body fluid and tissue samples. When the…”
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