Detection of two porcine circovirus type 2 genotypic groups in United States swine herds

Detection of two porcine circovirus type 2 genotypic groups in United States swine herds

In late 2005, sporadic cases of an acute onset disease of high mortality were observed in 10- to 16-week-old growing pigs among several swine herds of the United States. Tissues from the affected pigs in Kansas, Iowa, and North Carolina were examined, and porcine circovirus type 2 (PCV2) was detecte...

Full description

Saved in:
Bibliographic Details
Published in:Archives of virology Vol. 152; no. 5; pp. 1035 - 1044
Main Authors: Cheung, A.K, Lager, K.M, Kohutyuk, O.I, Vincent, A.L, Henry, S.C, Baker, R.B, Rowland, R.R, Dunham, A.G
Format: Journal Article
Language:English
Published: Wien Vienna : Springer-Verlag 01-05-2007
New York, NY Springer
Springer Nature B.V
Springer-Verlag
Subjects:
Amino acids
Animal diseases
Animal Husbandry
Animals
Biological and medical sciences
Brief Report
Circoviridae Infections - veterinary
Circoviridae Infections - virology
Circovirus - classification
Circovirus - genetics
Circovirus - isolation & purification
Epidemics
Fundamental and applied biological sciences. Psychology
genetic variation
Genome, Viral
Genomes
Hogs
Microbiology
Miscellaneous
Mortality
pathogen identification
Phylogeny
Pneumonia
Porcine circovirus
Proteins
Species Specificity
Swine
swine diseases
Swine Diseases - virology
United States
Veterinary medicine
viral diseases of animals and humans
Virology
Viruses
North Carolina
Iowa
Kansas
United States
North America
America
United States > US
Europe
Virus
Vertebrata
Mammalia
Swine
Circovirus
Porcine circovirus
Artiodactyla
Circoviridae
Veterinary
Detection
Ungulata
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In late 2005, sporadic cases of an acute onset disease of high mortality were observed in 10- to 16-week-old growing pigs among several swine herds of the United States. Tissues from the affected pigs in Kansas, Iowa, and North Carolina were examined, and porcine circovirus type 2 (PCV2) was detected consistently among these tissues. Phylogenetically, PCV2 can be divided into two major genotypic groups, PCV2-group 1 and PCV2-group 2. Whereas PCV2-group 1 isolates were detected in all the diseased animals, only two of the diseased animals harbored PCV2-group 2 isolates. This observation is important because PCV2-group 1 isolates had never been reported in the United States before (GenBank as of May 16, 2006), and they are closely related to the PCV2-group 1 isolates that have been described in Europe and Asia, previously. Our analysis revealed that each genotypic group contains a distinct stretch of nucleotide or amino acid sequence that may serve as a signature motif for PCV2-group 1 or PCV2-group 2 isolates.
Bibliography:http://dx.doi.org/10.1007/s00705-006-0909-6
http://hdl.handle.net/10113/9198
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-006-0909-6