Search Results - "Kohout, A."

An elastic plate model for wave attenuation and ice floe breaking in the marginal ice zone by Kohout, A. L., Meylan, M. H.

“…We present a model for wave attenuation in the marginal ice zone (MIZ) based on a two‐dimensional (one horizontal and one vertical dimension) multiple floating…”
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Storm-induced sea-ice breakup and the implications for ice extent by Kohout, A. L., Williams, M. J. M., Dean, S. M., Meylan, M. H.

“…Concurrent observations at multiple locations indicate that storm-generated ocean waves propagating through Antarctic sea ice can transport enough energy to…”
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A wave-based model for the marginal ice zone including a floe breaking parameterization by Dumont, D., Kohout, A., Bertino, L.

“…The marginal ice zone (MIZ) is the boundary between the open ocean and ice‐covered seas, where sea ice is significantly affected by the onslaught of ocean…”
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Marginal ice zone dynamics: future research perspectives and pathways by Bennetts, L G, Bitz, C M, Feltham, D L, Kohout, A L, Meylan, M H

“…Perspectives are discussed on future directions for the field of marginal ice zone (MIZ) dynamics, based on the extraordinary progress made over the past…”
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Assessing the Correlation between the Radiological, Macroscopic and Histological Examination of Degenerative Changes of Articular Surfaces in Knee Osteoarthritis with Varus Deformity by Waciakowski, D, Kohout, A, Brožík, J, Šponer, P

“…Our study aims to compare the results of preoperative radiography and intraoperative visual assessment of the cartilage with histological assessment of joint…”
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Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization by Kohout, Trudy A, Lefkowitz, Robert J

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β-Arrestin 1 and 2 Differentially Regulate Heptahelical Receptor Signaling and Trafficking by Kohout, Trudy A., Lin, Fang-Tsyr, Perry, Stephen J., Conner, David A., Lefkowitz, Robert J.

“…The two widely coexpressed isoforms of β-arrestin (termed β-arrestin 1 and 2) are highly similar in amino acid sequence. The β-arrestins bind phosphorylated…”
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Loss of immune escape mutations during persistent HCV infection in pregnancy enhances replication of vertically transmitted viruses by Honegger, Jonathan R, Kim, Seungtaek, Price, Aryn A, Kohout, Jennifer A, McKnight, Kevin L, Prasad, Mona R, Lemon, Stanley M, Grakoui, Arash, Walker, Christopher M

“…Here, Honegger et al . study two HCV-infected women through two consecutive pregnancies and chronicle T cell escape mutations in viral proteins that revert…”
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Regulation of Receptor Fate by Ubiquitination of Activated β2-Adrenergic Receptor and β-Arrestin by Shenoy, Sudha K., McDonald, Patricia H., Kohout, Trudy A., Lefkowitz, Robert J.

“…Although trafficking and degradation of several membrane proteins are regulated by ubiquitination catalyzed by E3 ubiquitin ligases, there has been little…”
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Differential Desensitization, Receptor Phosphorylation, β-Arrestin Recruitment, and ERK1/2 Activation by the Two Endogenous Ligands for the CC Chemokine Receptor 7 by Kohout, Trudy A., Nicholas, Shelby L., Perry, Stephen J., Reinhart, Greg, Junger, Sachiko, Struthers, R. Scott

“…Many members of the chemokine receptor family of G protein-coupled receptors utilize multiple endogenous ligands. However, differences between the signaling…”
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Additive effect of simultaneous continuous administration of degarelix and TAK-448 on LH suppression in a castrated rat model by Stalewski, Jacek, Hargrove, Diane M., Wolfe, Monica, Kohout, Trudy A., Kamal, Adeela

“…Gonadotropin releasing hormone (GnRH) analogs have long been used in androgen deprivation therapy (ADT) in the treatment of prostate cancer. Chronic…”
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Linear water wave propagation through multiple floating elastic plates of variable properties by Kohout, A.L., Meylan, M.H., Sakai, S., Hanai, K., Leman, P., Brossard, D.

“…We investigate the problem of linear water wave propagation under a set of elastic plates of variable properties. The problem is two-dimensional, but we allow…”
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Validation and application of a liquid chromatography–tandem mass spectrometric method for the simultaneous determination of testosterone and dihydrotestosterone in rat prostatic tissue using a 96-well format by O’Brien, Zhihong, Post, Noah, Brown, Michael, Madan, Ajay, Coon, Timothy, Luo, Rosa, Kohout, Trudy A.

“…A liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed to extract and quantify the androgen concentration in the rat prostate. This…”
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In situ observations of wave-induced sea ice breakup by Kohout, A.L., Williams, M.J.M., Toyota, T., Lieser, J., Hutchings, J.

“…Ocean waves can propagate hundreds of kilometers into sea ice, leaving behind a wake of broken ice floes. Three floe breakup events were observed during the…”
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N-Formyl Peptide Receptors Internalize but Do Not Recycle in the Absence of Arrestins by Vines, Charlotte M., Revankar, Chetana M., Maestas, Diane C., LaRusch, Leah L., Cimino, Daniel F., Kohout, Trudy A., Lefkowitz, Robert J., Prossnitz, Eric R.

“…Arrestins mediate phosphorylation-dependent desensitization, internalization, and initiation of signaling cascades for the majority of G protein-coupled…”
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β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis by Povsic, Thomas J., Kohout, Trudy A., Lefkowitz, Robert J.

“…β-arrestins (1 and 2) are widely expressed cytosolic proteins that play central roles in G protein-coupled receptor signaling. β-arrestin1 is also recruited to…”
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Regulation of Cysteinyl Leukotriene Type 1 Receptor Internalization and Signaling by Naik, Snehal, Billington, Charlotte K., Pascual, Rodolfo M., Deshpande, Deepak A., Stefano, Frank P., Kohout, Trudy A., Eckman, Delrae M., Benovic, Jeffrey L., Penn, Raymond B.

“…Cysteinyl leukotrienes activate the cysteinyl leukotriene type 1 receptor (CysLT1R) to regulate numerous cell functions important in inflammatory processes and…”
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Distinct Conformations of the Corticotropin Releasing Factor Type 1 Receptor Adopted following Agonist and Antagonist Binding Are Differentially Regulated by Perry, Stephen J., Junger, Sachiko, Kohout, Trudy A., Hoare, Sam R.J., Struthers, R. Scott, Grigoriadis, Dimitri E., Maki, Richard A.

“…The corticotropin releasing factor (CRF) type 1 receptor (CRF1) is a class B family G protein-coupled receptor that regulates the…”
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beta -Arrestins regulate protease-activated receptor-1 desensitization but not internalization or Down-regulation by Paing, May M, Stutts, Amy B, Kohout, Trudy A, Lefkowitz, Robert J, Trejo, JoAnn

“…The widely expressed beta-arrestin isoforms 1 and 2 bind phosphorylated G protein-coupled receptors (GPCRs) and mediate desensitization and internalization…”
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Stem cells regenerative properties on new rat spinal fusion model by Klíma, K, Vaněček, V, Kohout, A, Jiroušek, O, Foltán, R, Štulík, J, Machoň, V, Pavlíková, G, Jendelová, P, Syková, E, Šedý, J

“…Stem cells biology is one of the most frequent topic of physiological research of today. Spinal fusion represents common bone biology challenge. It is the…”
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