Search Results - "Kohler, Christian W"

A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma by Salaverria, Itziar, Martin-Guerrero, Idoia, Wagener, Rabea, Kreuz, Markus, Kohler, Christian W., Richter, Julia, Pienkowska-Grela, Barbara, Adam, Patrick, Burkhardt, Birgit, Claviez, Alexander, Damm-Welk, Christine, Drexler, Hans G., Hummel, Michael, Jaffe, Elaine S., Küppers, Ralf, Lefebvre, Christine, Lisfeld, Jasmin, Löffler, Markus, Macleod, Roderick A.F., Nagel, Inga, Oschlies, Ilske, Rosolowski, Maciej, Russell, Robert B., Rymkiewicz, Grzegorz, Schindler, Detlev, Schlesner, Matthias, Scholtysik, René, Schwaenen, Carsten, Spang, Rainer, Szczepanowski, Monika, Trümper, Lorenz, Vater, Inga, Wessendorf, Swen, Klapper, Wolfram, Siebert, Reiner

“…The genetic hallmark of Burkitt lymphoma (BL) is the t(8;14)(q24;q32) and its variants leading to activation of the MYC oncogene. It is a matter of debate…”
Get full text

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults by Salaverria, Itziar, Philipp, Claudia, Oschlies, Ilske, Kohler, Christian W., Kreuz, Markus, Szczepanowski, Monika, Burkhardt, Birgit, Trautmann, Heiko, Gesk, Stefan, Andrusiewicz, Miroslaw, Berger, Hilmar, Fey, Miriam, Harder, Lana, Hasenclever, Dirk, Hummel, Michael, Loeffler, Markus, Mahn, Friederike, Martin-Guerrero, Idoia, Pellissery, Shoji, Pott, Christiane, Pfreundschuh, Michael, Reiter, Alfred, Richter, Julia, Rosolowski, Maciej, Schwaenen, Carsten, Stein, Harald, Trümper, Lorenz, Wessendorf, Swen, Spang, Rainer, Küppers, Ralf, Klapper, Wolfram, Siebert, Reiner

“…The prognosis of germinal center–derived B-cell (GCB) lymphomas, including follicular lymphoma and diffuse large-B-cell lymphoma (DLBCL), strongly depends on…”
Get full text

The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma by Wagener, Rabea, Seufert, Julian, Raimondi, Francesco, Bens, Susanne, Kleinheinz, Kortine, Nagel, Inga, Altmüller, Janine, Thiele, Holger, Hübschmann, Daniel, Kohler, Christian W., Nürnberg, Peter, Au-Yeung, Rex, Burkhardt, Birgit, Horn, Heike, Leoncini, Lorenzo, Jaffe, Elaine S., Ott, German, Rymkiewicz, Grzegorz, Schlesner, Matthias, Russell, Robert B., Klapper, Wolfram, Siebert, Reiner

“…The new recently described provisional lymphoma category Burkitt-like lymphoma with 11q aberration comprises cases similar to Burkitt lymphoma (BL) on…”
Get full text

Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma by Klapper, Wolfram, Kreuz, Markus, Kohler, Christian W., Burkhardt, Birgit, Szczepanowski, Monika, Salaverria, Itziar, Hummel, Michael, Loeffler, Markus, Pellissery, Shoji, Woessmann, Wilhelm, Schwänen, Carsten, Trümper, Lorenz, Wessendorf, Swen, Spang, Rainer, Hasenclever, Dirk, Siebert, Reiner

“…Diffuse large B-cell lymphoma is the most frequent type of B-cell lymphoma in adult patients but also occurs in children. Patients are currently assigned to…”
Get full text

Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens by Masqué-Soler, Neus, Szczepanowski, Monika, Kohler, Christian W., Spang, Rainer, Klapper, Wolfram

Get full text

Cell‐of‐origin classification by gene expression and MYC‐rearrangements in diffuse large B‐cell lymphoma of children and adolescents by Szczepanowski, Monika, Lange, Jonas, Kohler, Christian W., Masque‐Soler, Neus, Zimmermann, Martin, Aukema, Sietse M., Altenbuchinger, Michael, Rehberg, Thorsten, Mahn, Friederike, Siebert, Reiner, Spang, Rainer, Burkhardt, Birgit, Klapper, Wolfram

“…Summary We present the largest series of diffuse large B‐cell lymphoma (DLBCL) in patients younger than 18 years analysed to date by gene expression profiling…”
Get full text

Spindle-Cell Variants of Primary Cutaneous Follicle Center B-Cell Lymphomas Are Germinal Center B-Cell Lymphomas by Gene Expression Profiling Using a Formalin-Fixed Paraffin-Embedded Specimen by Oschlies, Ilske, Kohler, Christian W., Szczepanowski, Monika, Koch, Karoline, Gontarewicz, Artur, Metze, Dieter, Hillen, Uwe, Richter, Julia, Spang, Rainer, Klapper, Wolfram

Get full text

Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma by Aukema, Sietse M, Kreuz, Markus, Kohler, Christian W, Rosolowski, Maciej, Hasenclever, Dirk, Hummel, Michael, Küppers, Ralf, Lenze, Dido, Ott, German, Pott, Christiane, Richter, Julia, Rosenwald, Andreas, Szczepanowski, Monika, Schwaenen, Carsten, Stein, Harald, Trautmann, Heiko, Wessendorf, Swen, Trümper, Lorenz, Loeffler, Markus, Spang, Rainer, Kluin, Philip M, Klapper, Wolfram, Siebert, Reiner

“…Chromosomal translocations affecting the MYC oncogene are the biological hallmark of Burkitt lymphomas but also occur in a subset of other mature B-cell…”
Get full text

Clinical and pathological features of Burkitt lymphoma showing expression of BCL2 – an analysis including gene expression in formalin‐fixed paraffin‐embedded tissue by Masqué‐Soler, Neus, Szczepanowski, Monika, Kohler, Christian W., Aukema, Sietse M., Nagel, Inga, Richter, Julia, Siebert, Reiner, Spang, Rainer, Burkhardt, Birgit, Klapper, Wolfram

“…Summary The differential diagnosis between Burkitt lymphoma (BL) and diffuse large B‐cell lymphoma (DLBCL) can be challenging. BL has been reported to express…”
Get full text

SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients by Schif, Birgit, Lennerz, Jochen K, Kohler, Christian W, Bentink, Stefan, Kreuz, Markus, Melzner, Ingo, Ritz, Olga, Trümper, Lorenz, Loeffler, Markus, Spang, Rainer, Möller, Peter

“…Suppressor of cytokine signaling 1 (SOCS1) is frequently mutated in primary mediastinal and diffuse large B-cell lymphomas (DLBCL). Currently, the prognostic…”
Get full text

Clinical and pathological features of Burkitt lymphoma showing expression of BCL 2 – an analysis including gene expression in formalin‐fixed paraffin‐embedded tissue by Masqué‐Soler, Neus, Szczepanowski, Monika, Kohler, Christian W., Aukema, Sietse M., Nagel, Inga, Richter, Julia, Siebert, Reiner, Spang, Rainer, Burkhardt, Birgit, Klapper, Wolfram

“…Summary The differential diagnosis between Burkitt lymphoma ( BL ) and diffuse large B‐cell lymphoma ( DLBCL ) can be challenging. BL has been reported to…”
Get full text

Therapeutic targets and microenvironment in sequential biopsies of classical Hodgkin lymphoma at diagnosis and relapse by Schnitter, Antje, Kohler, Christian W., Reddemann, Katharina, Reinke, Sarah, Thorns, Christoph, Fend, Falko, Federmann, Birgit, Möller, Peter, Szczepanowski, Monika, Spang, Rainer, Klapper, Wolfram

“…Classical Hodgkin lymphoma is dominated by the non-neoplastic microenvironment, while the neoplastic Hodgkin-Reed-Sternberg cells compose only a minority of…”
Get full text

SOCS1 Mutation Subtypes Predict Divergent Outcomes in DLBCL Patients by Lennerz, Jochen K, Schif, Birgit, Kohler, Christian W, Bentink, Stefan, Kreuz, Markus, Melzner, Ingo, Trümper, Lorenz, Löffler, Markus, Spang, Rainer, Moeller, Peter

“…Abstract 419 Suppressor of cytokine signaling 1 (SOCS1) is frequently mutated in Hodgkin, primary mediastinal and diffuse large B-cell lymphomas (DLBCL). In…”
Get full text