Search Results - "Kohen, Ron"

Polyphenols activate Nrf2 in astrocytes via H2O2, semiquinones, and quinones by Erlank, Hilla, Elmann, Anat, Kohen, Ron, Kanner, Joseph

“…Polyphenols, which occur both in edible plants and in foodstuff, have been reported to exert a wide range of health effects; however, the mechanism of action…”
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novel function of red wine polyphenols in humans: prevention of absorption of cytotoxic lipid peroxidation products by Gorelik, Shlomit, Ligumsky, Moshe, Kohen, Ron, Kanner, Joseph

“…Current evidence supports a contribution of polyphenols to the prevention of cardiovascular disease, but their mechanisms of action are not understood. We…”
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Exploitation of alternative skin models from academia to industry: proposed functional categories to answer needs and regulation demands by Portugal-Cohen, Meital, Cohen, Dror, Kohen, Ron, Oron, Miriam

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Polyphenols enhance total oxidant-scavenging capacities of human blood by binding to red blood cells by Koren, Erez, Kohen, Ron, Ginsburg, Isaac

“…The present study offers a new look at the role of erythrocytes and of erythrocytes-polyphenol complexes as potent 'sinks' for reactive oxygen species. We…”
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The Cutaneous Physiological Redox: Essential to Maintain but Difficult to Define by Ron-Doitch, Sapir, Kohen, Ron

“…Skin is a unique tissue, possessing extremely efficient protective and regulative mechanisms, similar only to the gut and lungs. These tissues serve as an…”
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The Stomach as a “Bioreactor”: When Red Meat Meets Red Wine by Gorelik, Shlomit, Ligumsky, Moshe, Kohen, Ron, Kanner, Joseph

“…To determine the stomach bioreactor capability for food oxidation or antioxidation, rats were fed red turkey meat cutlets (meal A) or red turkey meat cutlets…”
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Coffee polyphenols protect human plasma from postprandial carbonyl modifications by Sirota, Roman, Gorelik, Shlomit, Harris, Raviv, Kohen, Ron, Kanner, Joseph

“…The antioxidant capability of coffee polyphenols to inhibit red‐meat lipid peroxidation in stomach medium and absorption into blood of malondialdehyde (MDA) in…”
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Can nitroxides evoke the Keap1–Nrf2–ARE pathway in skin? by Ben Yehuda Greenwald, Maya, Anzi, Shira, Ben Sasson, Shmuel, Bianco-Peled, Havazelet, Kohen, Ron

“…Nitroxides are stable cyclic radicals of diverse size, charge, and lipophilicity. They are cell-permeative, which effectively protects cells, tissues, isolated…”
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A rational approach to prevent postprandial modification of LDL by dietary polyphenols by Gorelik, Shlomit, Kanner, Joseph, Schurr, Daniel, Kohen, Ron

“…Food may undergo enhanced oxidation in the stomach leading to increases in the generation of deleterious lipid peroxidation products. Following meat…”
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A Cobalt-Based Tetrazolium Salts Reduction Test To Assay Polyphenols by Koren, Erez, Kohen, Ron, Ginsburg, Isaac

“…A novel assay was developed to measure the capacity of polyphenols to chelate cobalt(II) by using the reduction of the tetrazolium salts, NBT (nitroblue…”
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The oxidant-scavenging abilities in the oral cavity may be regulated by a collaboration among antioxidants in saliva, microorganisms, blood cells and polyphenols: a chemiluminescence-based study by Ginsburg, Isaac, Kohen, Ron, Shalish, Miri, Varon, David, Shai, Ella, Koren, Erez

“…Saliva has become a central research issue in oral physiology and pathology. Over the evolution, the oral cavity has evolved the antioxidants uric acid,…”
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The endocannabinoid 2-AG protects the blood–brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines by Panikashvili, David, Shein, Na'ama A., Mechoulam, Raphael, Trembovler, Victoria, Kohen, Ron, Alexandrovich, Alexander, Shohami, Esther

“…Endocannabinoids are involved in neuroprotection through numerous biochemical pathways. We have shown that the endocannabinoid 2-arachidonoyl glycerol (2-AG)…”
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Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger by Tan, Dun-xian, Reiter, Russel J, Manchester, Lucien C, Yan, Mei-ting, El-Sawi, Mamdouh, Sainz, Rosa M, Mayo, Juan C, Kohen, Ron, Allegra, Mario, Hardeland, Rudiger

“…Melatonin was found to be a potent free radical scavenger in 1993. Since then over 800 publications have directly or indirectly confirmed this observation…”
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Neuroprotection by cord blood neural progenitors involves antioxidants, neurotrophic and angiogenic factors by Arien-Zakay, Hadar, Lecht, Shimon, Bercu, Marian M., Tabakman, Rinat, Kohen, Ron, Galski, Hanan, Nagler, Arnon, Lazarovici, Philip

“…Human umbilical cord blood (HUCB) is a valuable source for cell therapy since it confers neuroprotection in stroke animal models. However, the responsible…”
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Exposure of human keratinocytes to ischemia, hyperglycemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase by Portugal-Cohen, Meital, Kohen, Ron

“…Abstract Background Diabetes mellitus is characterized by a chronic hyperglycemia and might cause skin pathologies resulting from an ischemic insult. A variety…”
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Oxidative stress in childhood—in health and disease states by Granot, Esther, Kohen, Ron

“…The accumulated information concerning the involvement of reactive oxygen species in many clinical disorders and disease states has led to the potential for…”
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Nrf2-keap Pathway Role in Cutaneous Redox maintenance; Biological, Environmental and Chemical activators by Kohen, Ron

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eDNA-Mediated Cutaneous Protection Against UVB Damage Conferred by Staphylococcal Epidermal Colonization by Ron-Doitch, Sapir, Frušić-Zlotkin, Marina, Soroka, Yoram, Duanis-Assaf, Danielle, Amar, Dalit, Kohen, Ron, Steinberg, Doron

“…The human skin is a lush microbial habitat which is occupied by a wide array of microorganisms. Among the most common inhabitants are spp., namely and, in ≈20%…”
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Cocaine induces oxidative damage to skin via xanthine oxidase and nitric oxide synthase by Portugal-Cohen, Meital, Numa, Ran, Yaka, Rami, Kohen, Ron

“…Abstract Background Heavy cocaine abusers are known to develop adverse skin manifestations, however, a possible mechanism for such damages has not yet been…”
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Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia by Tabakman, Rinat, Lazarovici, Philip, Kohen, Ron

“…The development of neuroprotective drugs against ischemic insults is hampered by the lack of pharmacological in vitro models. We developed an ischemic model…”
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