Search Results - "Koh, Sehwon"

From “ES-like” cells to induced pluripotent stem cells: A historical perspective in domestic animals by Koh, Sehwon, Piedrahita, Jorge A.

“…Pluripotent stem cells such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) provide great potential as cell sources for gene editing…”
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An Antimicrobial Peptide and Its Neuronal Receptor Regulate Dendrite Degeneration in Aging and Infection by E, Lezi, Zhou, Ting, Koh, Sehwon, Chuang, Marian, Sharma, Ruchira, Pujol, Nathalie, Chisholm, Andrew D., Eroglu, Cagla, Matsunami, Hiroaki, Yan, Dong

“…Infections have been identified as possible risk factors for aging-related neurodegenerative diseases, but it remains unclear whether infection-related immune…”
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High mobility group A2 (HMGA2) deficiency in pigs leads to dwarfism, abnormal fetal resource allocation, and cryptorchidism by Chung, Jaewook, Zhang, Xia, Collins, Bruce, Sper, Renan B., Gleason, Katherine, Simpson, Sean, Koh, Sehwon, Sommer, Jeffrey, Flowers, William L., Petters, Robert M., Piedrahita, Jorge A.

“…Expression of HMGA2 is strongly associated with body size and growth in mice and humans. In mice, inactivation of one or both alleles of Hmga2 results in…”
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Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins by Koh, Sehwon, Kim, Namsoo, Yin, Henry H, Harris, Ian R, Dejneka, Nadine S, Eroglu, Cagla

“…Cell therapy demonstrates great potential for the treatment of neurological disorders. Human umbilical tissue-derived cells (hUTCs) were previously shown to…”
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Generation of a Stable Transgenic Swine Model Expressing a Porcine Histone 2B-eGFP Fusion Protein for Cell Tracking and Chromosome Dynamics Studies by Sper, Renan B, Koh, Sehwon, Zhang, Xia, Simpson, Sean, Collins, Bruce, Sommer, Jeff, Petters, Robert M, Caballero, Ignacio, Platt, Jeff L, Piedrahita, Jorge A

“…Transgenic pigs have become an attractive research model in the field of translational research, regenerative medicine, and stem cell therapy due to their…”
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Growth requirements and chromosomal instability of induced pluripotent stem cells generated from adult canine fibroblasts by Koh, Sehwon, Thomas, Rachael, Tsai, Shengdar, Bischoff, Steve, Lim, Ji-Hey, Breen, Matthew, Olby, Natasha J, Piedrahita, Jorge A

“…In mice and humans, it has been shown that embryonic and adult fibroblasts can be reprogrammed into pluripotency by introducing 4 transcription factors,…”
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Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1 by Risher, W Christopher, Kim, Namsoo, Koh, Sehwon, Choi, Ji-Eun, Mitev, Petar, Spence, Erin F, Pilaz, Louis-Jan, Wang, Dongqing, Feng, Guoping, Silver, Debra L, Soderling, Scott H, Yin, Henry H, Eroglu, Cagla

“…Astrocytes control excitatory synaptogenesis by secreting thrombospondins (TSPs), which function via their neuronal receptor, the calcium channel subunit…”
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Neuronal IL‐4Rα modulates neuronal apoptosis and cell viability during the acute phases of cerebral ischemia by Lee, Han Kyu, Koh, Sehwon, Lo, Donald C., Marchuk, Douglas A.

“…Ischemic stroke caused by an embolus or local thrombosis results in neural tissue damage (an infarct) in the territory of the occluded cerebral artery. Decades…”
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Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity by Koh, Sehwon, Chen, William J, Dejneka, Nadine S, Harris, Ian R, Lu, Bin, Girman, Sergey, Saylor, Joshua, Wang, Shaomei, Eroglu, Cagla

“…Human umbilical tissue-derived cells (hUTC or palucorcel) are currently under clinical investigation for the treatment of geographic atrophy, a late stage of…”
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Generation of Induced Pluripotent Stem Cells (iPSCs) from Adult Canine Fibroblasts by Koh, Sehwon, Piedrahita, Jorge A

“…Induced pluripotent stem cells hold great potential in regenerative medicine as it enables to generate pluripotent stem cells from any available cell types…”
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Impaired Skeletal Development by Disruption of Presenilin-1 in Pigs and Generation of Novel Pig Models for Alzheimer's Disease by Uh, Kyungjun, Monarch, Kaylynn, Reese, Emily D, Rodriguez, Katherine, Yoon, Junchul, Spate, Lee D, Samuel, Melissa S, Koh, Sehwon, Chen, Paula R, Jarome, Timothy J, Allen, Timothy A, Prather, Randall S, Lee, Kiho

“…Presenilin 1 (PSEN1) is one of the genes linked to the prevalence of early onset Alzheimer's disease. In mice, inactivation of Psen1 leads to developmental…”
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Improved Chondrogenic Potential and Proteomic Phenotype of Porcine Chondrocytes Grown in Optimized Culture Conditions by Koh, Sehwon, Purser, Molly, Wysk, Richard, Piedrahita, Jorge A

“…For successful cartilage tissue engineering, the ability to generate a high number of chondrocytes in vitro while avoiding terminal differentiation or…”
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Evaluation of gene expression and DNA copy number profiles of adipose tissue-derived stromal cells and consecutive neurosphere-like cells generated from dogs with naturally occurring spinal cord injury by Lim, Ji-Hey, Koh, Sehwon, Thomas, Rachael, Breen, Matthew, Olby, Natasha J

“…OBJECTIVE To evaluate gene expression and DNA copy number in adipose tissue-derived stromal cells (ADSCs) and in ADSC-derived neurosphere-like cell clusters…”
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STIM1 regulates store-operated Ca2+ entry in oocytes by Koh, Sehwon, Lee, Kiho, Wang, Chunmin, Cabot, Ryan A, Machaty, Zoltan

“…The single transmembrane-spanning Ca(2+)-binding protein, STIM1, has been proposed to function as a Ca(2+) sensor that links the endoplasmic reticulum to the…”
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Generation of Putative Induced Pluripotent Stem Cells (iPS) from Adult Canine Fibroblast by Koh, Sehwon, Tsai, Shengdar, Bischoff, Steve, Olby, Natasha, Piedrahita, Jorge

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Isolation and characterization of neural progenitor cells from adult canine brains by Lim, Ji-Hey, Koh, Sehwon, Olby, Natasha J, Piedrahita, Jorge, Mariani, Christopher L

“…Objective: To isolate and characterize neural stem and progenitor cell populations in the brain of adult dogs. Animals: 7 healthy adult dogs. Procedures: Dogs…”
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Stem cell sources for Regenerative Medicine and Cartilage Tissue Engineering by Koh, Sehwon

“…Stem cells have been studied widely as a potential resource for regenerative medicine as they can proliferate for long-term while maintaining differentiation…”
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Generation of Putative Induced Pluripotent Stem Cells from Adult Canine Fibroblast by Three Factor Reprogramming (Oct3/4, Klf4, and Sox2) by Koh, Sehwon, Tsai, Shengdar, Bischoff, Steve, Olby, Natasha J., Piedrahita, Jorge

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Canine iPSC generation with non-integrative vectors by Gonçalves, Natalia J, Koh, Sehwon, Bressan, Fabiana F, Martins, Daniele S, Meirelles, Flávio V, Piedrahyta, Jorge, Ambrósio, Carlos E

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STIM1 regulates store-operated Ca super(2+) entry in oocytes by Koh, Sehwon, Lee, Kiho, Wang, Chunmin, Cabot, Ryan A, Machaty, Zoltan

“…The single transmembrane-spanning Ca super(2+)-binding protein, STIM1, has been proposed to function as a Ca super(2+) sensor that links the endoplasmic…”
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