Search Results - "Koh, L Y"

A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds by Yoshida, Minoru, Giaever, Guri, Gresham, David, Nishimura, Shinichi, Gray, Christopher A, Porter, Justin, Natarajan, Paramasivam, Graham, Todd R, Magtanong, Leslie, Boone, Charles, Koh, Judice L Y, Andersen, Raymond J, Botstein, David, Ho, Cheuk Hei, Nislow, Corey, Andrews, Brenda, Barker, Sarah L

“…Knowing a drug's mode of action is invaluable for informing drug discovery efforts. Ho et al . construct an optimized yeast genomic library that enables rapid…”
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Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases by Ho, Beatrice Xuan, Pang, Jeremy Kah Sheng, Chen, Ying, Loh, Yuin-Han, An, Omer, Yang, Henry He, Seshachalam, Veerabrahma Pratap, Koh, Judice L Y, Chan, Woon-Khiong, Ng, Shi Yan, Soh, Boon Seng

“…Tissue organoids generated from human pluripotent stem cells are valuable tools for disease modelling and to understand developmental processes. While recent…”
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Capsular Serotype K1 or K2, Rather than magA and rmpA, Is a Major Virulence Determinant for Klebsiella pneumoniae Liver Abscess in Singapore and Taiwan by Yeh, Kuo-Ming, Kurup, A, Siu, L.K, Koh, Y.L, Fung, Chang-Phone, Lin, Jung-Chung, Chen, Te-Li, Chang, Feng-Yee, Koh, Tse-Hsien

“…Capsular serotypes, magA, and rmpA have been documented in high prevalence for Klebsiella pneumoniae liver abscess. To investigate the regional difference and…”
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COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines by Koh, Judice L. Y., Brown, Kevin R., Sayad, Azin, Kasimer, Dahlia, Ketela, Troy, Moffat, Jason

“…Genome-wide pooled shRNA screens enable global identification of the genes essential for cancer cell survival and proliferation and provide a 'functional…”
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Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes by Dixon, Scott J, Fedyshyn, Yaroslav, Koh, Judice L.Y, Prasad, T.S. Keshava, Chahwan, Charly, Chua, Gordon, Toufighi, Kiana, Baryshnikova, Anastasija, Hayles, Jacqueline, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Myers, Chad L, Pandey, Akhilesh, Durocher, Daniel, Andrews, Brenda J, Boone, Charles

“…Synthetic lethal genetic interaction networks define genes that work together to control essential functions and have been studied extensively in Saccharomyces…”
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Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass by Sun, Chun Xiang, Downey, Gregory P., Zhu, Fei, Koh, Adeline L.Y., Thang, Herman, Glogauer, Michael

“…Although both of the small Rho guanosine triphosphatases (GTPases) Rac1 and Rac2 have been demonstrated to play a role in chemotaxis, the precise and possible…”
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DRYGIN: a database of quantitative genetic interaction networks in yeast by Koh, Judice L.Y, Ding, Huiming, Costanzo, Michael, Baryshnikova, Anastasia, Toufighi, Kiana, Bader, Gary D, Myers, Chad L, Andrews, Brenda J, Boone, Charles

“…Genetic interactions are highly informative for deciphering the underlying functional principles that govern how genes control cell processes. Recent…”
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Factors associated with impaired color vision without retinopathy amongst people with type 2 diabetes mellitus: a cross-sectional study by Tan, N C, Yip, W F, Kallakuri, S, Sankari, U, Koh, Y L E

“…Patients with type 2 diabetes mellitus (T2DM) may develop color vision impairment. This study aimed to determine the prevalence and factors associated with…”
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Asthma care based on Chronic Care Model in an aging Asian community by Zheng, L. F., Koh, Y. L. E., Sankari, U., Tan, N. C.

“…To cope with the higher prevalence of asthma and other non-communicable diseases without compromising on quality of care, a Singapore public primary care…”
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Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time by Chia, Shumei, Low, Joo-Leng, Zhang, Xiaoqian, Kwang, Xue-Lin, Chong, Fui-Teen, Sharma, Ankur, Bertrand, Denis, Toh, Shen Yon, Leong, Hui-Sun, Thangavelu, Matan T., Hwang, Jacqueline S. G., Lim, Kok-Hing, Skanthakumar, Thakshayeni, Tan, Hiang-Khoon, Su, Yan, Hui Choo, Siang, Hentze, Hannes, Tan, Iain B. H., Lezhava, Alexander, Tan, Patrick, Tan, Daniel S. W., Periyasamy, Giridharan, Koh, Judice L. Y., Gopalakrishna Iyer, N., DasGupta, Ramanuj

“…Genomics-driven cancer therapeutics has gained prominence in personalized cancer treatment. However, its utility in indications lacking biomarker-driven…”
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Corrigendum: Introducing a healthcare-assistive robot in primary care: a preliminary questionnaire survey by Tan, N C, Yusoff, Y, Koot, D, Lau, Q C, Lim, H, Hui, T F, Cher, H Y, Tan, P Y A, Koh, Y L E

“…[This corrects the article DOI: 10.3389/frobt.2023.1123153.]…”
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Introducing a healthcare-assistive robot in primary care: a preliminary questionnaire survey by Tan, N C, Yusoff, Y, Koot, D, Lau, Q C, Lim, H, Hui, T F, Cher, H Y, Tan, P Y A, Koh, Y L E

“…A Healthcare-assistive Infection-control RObot (HIRO) is a healthcare-assistive robot that is deployed in an outpatient primary care clinic to sanitise the…”
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Methods for prediction of peptide binding to MHC molecules: a comparative study by Yu, Kun, Petrovsky, Nikolai, Schönbach, Christian, Koh, Judice Y L, Brusic, Vladimir

“…A variety of methods for prediction of peptide binding to major histocompatibility complex (MHC) have been proposed. These methods are based on binding motifs,…”
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Cross-cultural adaptation and psychometric evaluation of the Malay version of the Neck Disability Index by Lim, H. H. R., Tan, S. T., Tang, Z. Y., Yang, M., Koh, E. Y. L, Koh, K. H.

“…Translating the Neck Disability Index (NDI) into the Malay language (NDI-M); evaluation of psychometric properties in patients with neck pain. The NDI-M was…”
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Dragon Promoter Finder: recognition of vertebrate RNA polymerase II promoters by Bajic, Vladimir B., Seah, Seng Hong, Chong, Allen, Zhang, Guanglan, Koh, Judice L. Y., Brusic, Vladimir

“…Dragon Promoter Finder (DPF) locates RNA polymerase II promoters in DNA sequences of vertebrates by predicting Transcription Start Site (TSS) positions. DPF’s…”
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AllerTool: a web server for predicting allergenicity and allergic cross-reactivity in proteins by Zhang, Zong Hong, Koh, Judice L. Y., Zhang, Guang Lan, Choo, Khar Heng, Tammi, Martti T., Tong, Joo Chuan

“…Assessment of potential allergenicity and patterns of cross-reactivity is necessary whenever novel proteins are introduced into human food chain. Current…”
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Development of zirconia-glass ionomer cement composites by Gu, Y.W., Yap, A.U.J., Cheang, P., Koh, Y.L., Khor, K.A.

“…Yttria stabilized zirconia (YSZ) powders were used for the replacement of amalgam alloy in Miracle Mix on a volume basis, in order to improve the mechanical…”
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A comprehensive platform for highly multiplexed mammalian functional genetic screens by Ketela, Troy, Heisler, Lawrence E, Brown, Kevin R, Ammar, Ron, Kasimer, Dahlia, Surendra, Anuradha, Ericson, Elke, Blakely, Kim, Karamboulas, Dina, Smith, Andrew M, Durbic, Tanja, Arnoldo, Anthony, Cheung-Ong, Kahlin, Koh, Judice L Y, Gopal, Shuba, Cowley, Glenn S, Yang, Xiaoping, Grenier, Jennifer K, Giaever, Guri, Root, David E, Moffat, Jason, Nislow, Corey

“…Genome-wide screening in human and mouse cells using RNA interference and open reading frame over-expression libraries is rapidly becoming a viable…”
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Effects of local stiffness changes and delamination on Lamb wave transmission using surface-mounted piezoelectric transducers by Koh, Y.L, Chiu, W.K, Rajic, N

“…The paper presents a set of numerical results on the use of surface mounted piezoelectric transducers to analyse the effects of impact damage and delamination…”
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Integrity assessment of composite repair patch using propagating Lamb waves by Koh, Y.L, Chiu, W.K, Rajic, N

“…In this paper, results from a numerical study on the use of Lamb wave propagation for the detection of disbond growth beneath a composite repair patch are…”
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