Search Results - "Koh, Jim"

Utility of p16 Immunohistochemistry for the Identification of Lynch Syndrome by PAYA, Artemio, ALENDA, Cristina, LLOR, Xavier, ANDREU, Montserrat, KOH, Jim, ENDERS, Greg H, BENLLOCH, Susana, JOVER, Rodrigo, PEREZ-CARBONELL, Lucía, ROJAS, Estefanía, SOTO, José-Luis, GUILLEN, Carmen, CASTILLEJO, Adela, BARBERA, Victor M, CARRATO, Alfredo, CASTELLS, Antoni

“…Purpose: Immunohistochemistry for mismatch repair proteins has shown utility in the identification of Lynch syndrome, but majority of tumors with loss of MLH1…”
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Molecular Genetic Correlates of p16, cdk4, and pRb Immunohistochemistry in Glioblastomas by BURNS, KAREN L, UEKI, KEISUKE, JHUNG, SARAH L, KOH, JIM, LOUIS, DAVID N

“…The vast majority of glioblastomas have CDKN2A, CDK4, or RB gene alterations that perturb the pl6-cdk4-pRb cell cycle regulatory cascade. To explore whether…”
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Induction of the Tumor-Suppressor p16INK4a within Regenerative Epithelial Crypts in Ulcerative Colitis by Furth, Emma E., Gustafson, Karen S., Dai, Charlotte Y., Gibson, Steven L., Menard-Katcher, Paul, Chen, Tina, Koh, Jim, Enders, Greg H.

“…p16INK4a is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced in…”
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Early growth response 2 (EGR2) is a novel regulator of the senescence programme by Tyler, Eleanor J., Gutierrez del Arroyo, Ana, Hughes, Bethany K., Wallis, Ryan, Garbe, James C., Stampfer, Martha R., Koh, Jim, Lowe, Robert, Philpott, Michael P., Bishop, Cleo L.

“…Senescence, a state of stable growth arrest, plays an important role in ageing and age‐related diseases in vivo. Although the INK4/ARF locus is known to be…”
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Primary cilium-dependent and -independent Hedgehog signaling inhibits p16(INK4A) by Bishop, Cleo L, Bergin, Ann-Marie H, Fessart, Delphine, Borgdorff, Viola, Hatzimasoura, Elizabeth, Garbe, James C, Stampfer, Martha R, Koh, Jim, Beach, David H

“…In a genome-wide siRNA analysis of p16(INK4a) (p16) modulators, we identify the Hedgehog (Hh) pathway component SUFU and formally demonstrate that Hh signaling…”
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Primary Cilium-Dependent and -Independent Hedgehog Signaling Inhibits p16INK4A by Bishop, Cleo L., Bergin, Ann-Marie H., Fessart, Delphine, Borgdorff, Viola, Hatzimasoura, Elizabeth, Garbe, James C., Stampfer, Martha R., Koh, Jim, Beach, David H.

“…In a genome-wide siRNA analysis of p16INK4a (p16) modulators, we identify the Hedgehog (Hh) pathway component SUFU and formally demonstrate that Hh signaling…”
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Induction of the tumor-suppressor p16(INK4a) within regenerative epithelial crypts in ulcerative colitis by Furth, Emma E, Gustafson, Karen S, Dai, Charlotte Y, Gibson, Steven L, Menard-Katcher, Paul, Chen, Tina, Koh, Jim, Enders, Greg H

“…p16(INK4a) is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced…”
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Prevalence of Germ-Line Mutations in p16, p19ARF, and CDK4 in Familial Melanoma: Analysis of a Clinic-Based Population by FitzGerald, Michael G., Harkin, D. Paul, Silva-Arrieta, Sandra, MacDonald, Deborah J., Lucchina, Leslie C., Unsal, Hilal, O'Neill, Erin, Koh, Jim, Finkelstein, Dianne M., Isselbacher, Kurt J., Sober, Arthur J., Haber, Daniel A.

“…Five to ten percent of individuals with melanoma have another affected family member, suggesting familial predisposition. Germ-line mutations in the…”
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Repetitive avalanche cycling of low-voltage power trench n-MOSFETs by Alatise, Olayiwola, Kennedy, Ian, Petkos, George, Heppenstall, Keith, Khan, Khalid, Parkin, Jim, Koh, Adrian, Rutter, Phil

“…Low voltage discrete power trench n-MOSFETs in TO-220 packages have been subjected to over 200 million cycles of repetitive unclamped inductive switching (UIS)…”
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Induction of the Tumor-Suppressor p16INK4a within Regenerative Epithelial Crypts in Ulcerative Colitis1 by Furth, Emma E, Gustafson, Karen S, Dai, Charlotte Y, Gibson, Steven L, Menard-Katcher, Paul, Chen, Tina, Koh, Jim, Enders, Greg H

“…p16 INK4a is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced…”
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p16 inhibition of transformed and primary squamous epithelial cells by Enders, G H, Koh, J, Missero, C, Rustgi, A K, Harlow, E

“…We and others have recently shown that p16 can potently and specifically inhibit progression through the G1 phase of the replicative cycle in cells that…”
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P16 methylation: An early event in hepatocellular carcinogenesis by Anders, Robert A., Bissonnette, Marc, Brasitus, Thomas A., Yaremko, M. Lisa, Koh, Jim, Brunt, E., Hart, John A.

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p16INK4a Expression begins early in human colon neoplasia and correlates inversely with markers of cell proliferation by Dai, Charlotte Y., Furth, Emma E., Mick, Rosemarie, Koh, Jim, Takayama, Tetsuji, Niitsu, Yoshiro, Enders, Greg H.

“…Background &Aims: p16INK4a is a cell cycle inhibitor and a major tumor-suppressor protein, but the regulation of p16INK4a is poorly understood and the…”
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Estimated prevalence and risk factor for age-related maculopathy by Roh, Mi In, Kim, Ji Hyun, Byeon, Suk Ho, Koh, Hyoung Jun, Lee, Sung Chul, Kwon, Oh Woong

“…To assess the estimate prevalence and risk factors for age-related maculopathy (ARM) in Seoul, Korea. We examined 9,530 subjects with, 40 years of age or older…”
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