Search Results - "Koh, Casslynn W. Q."
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Atlas of quantitative single-base-resolution N 6 -methyl-adenine methylomes
Published in Nature communications (10-12-2019)“…Various methyltransferases and demethylases catalyse methylation and demethylation of N -methyladenosine (m6A) and N ,2'-O-dimethyladenosine (m6Am) but precise…”
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Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore
Published in Nature biotechnology (01-11-2021)“…RNA modifications, such as N 6 -methyladenosine (m 6 A), modulate functions of cellular RNA species. However, quantifying differences in RNA modifications has…”
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METTL4 catalyzes m6Am methylation in U2 snRNA to regulate pre-mRNA splicing
Published in Nucleic acids research (18-09-2020)“…Abstract N 6-methylation of 2′-O-methyladenosine (Am) in RNA occurs in eukaryotic cells to generate N6,2′-O-dimethyladenosine (m6Am). Identification of the…”
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Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes
Published in Nature communications (10-12-2019)“…Various methyltransferases and demethylases catalyse methylation and demethylation of N 6 -methyladenosine (m6A) and N 6 ,2′-O-dimethyladenosine (m6Am) but…”
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Single-nucleotide-resolution sequencing of human N6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genome
Published in Nucleic acids research (14-12-2018)“…Abstract N 6-methyldeoxyadenosine (6mA) is a well-characterized DNA modification in prokaryotes but reports on its presence and function in mammals have been…”
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