Search Results - "Koguchi, Ken"

Induction of cyclooxygenase‐2 in reactive glial cells by the CD40 pathway: relevance to amyotrophic lateral sclerosis by Okuno, Tatsusada, Nakatsuji, Yuji, Kumanogoh, Atsushi, Koguchi, Ken, Moriya, Masayuki, Fujimura, Harutoshi, Kikutani, Hitoshi, Sakoda, Saburo

“…An inflammatory process in association with reactive gliosis has been suggested to play an important role in the pathogenesis of amyotrophic lateral sclerosis…”
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Microglial cell cycle-associated proteins control microglial proliferation in vivo and in vitro and are regulated by GM-CSF and density-dependent inhibition by Koguchi, Ken, Nakatsuji, Yuji, Okuno, Tatsusada, Sawada, Makoto, Sakoda, Saburo

“…Hyperplasia of microglia is one characteristic of reactive gliosis, which is observed in various pathologic conditions in the central nervous system (CNS). To…”
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HTLV-I-associated myelopathy manifested after renal transplantation by Nakatsuji, Yuji, Sugai, Fuminobu, Watanabe, Shohei, Kaido, Misako, Koguchi, Ken, Abe, Kazuo, Sakoda, Saburo

“…We report a patient with HTLV-I-associated myelopathy (HAM), who developed symptoms of myelopathy 4 years after cadaveric renal transplantation. Since he was…”
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TIM‐3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines by Hastings, William D., Anderson, David E., Kassam, Nasim, Koguchi, Ken, Greenfield, Edward A., Kent, Sally C., Zheng, Xin Xiao, Strom, Terry B., Hafler, David A., Kuchroo, Vijay K.

“…TIM‐3 is a molecule selectively expressed on a subset of murine IFN‐γ‐secreting T helper 1 (Th1) cells but not Th2 cells, and regulates Th1 immunity and…”
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Modulation of astrocyte proliferation by cyclin-dependent kinase inhibitor p27Kip1 by Koguchi, Ken, Nakatsuji, Yuji, Nakayama, Kei-Ichi, Sakoda, Saburo

“…We previously demonstrated that type 1 astrocytes exhibited homotypic cell contact‐dependent inhibition of proliferation with increased expression of…”
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Dysregulated T cell expression of TIM3 in multiple sclerosis by Koguchi, Ken, Anderson, David E, Yang, Li, O'Connor, Kevin C, Kuchroo, Vijay K, Hafler, David A

“…T cell immunoglobulin- and mucin domain-containing molecule (TIM)3 is a T helper cell (Th)1-associated cell surface molecule that regulates Th1 responses and…”
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Three-Year Follow-Up of High-Dose Ubiquinol Supplementation in a Case of Familial Multiple System Atrophy with Compound Heterozygous COQ2 Mutations by Mitsui, Jun, Koguchi, Ken, Momose, Toshimitsu, Takahashi, Miwako, Matsukawa, Takashi, Yasuda, Tsutomu, Tokushige, Shin-ichi, Ishiura, Hiroyuki, Goto, Jun, Nakazaki, Shigeaki, Kondo, Tomoyoshi, Ito, Hidefumi, Yamamoto, Yorihiro, Tsuji, Shoji

“…We report a 3-year follow-up of high-dose ubiquinol supplementation in a case of familial multiple system atrophy (MSA) with compound heterozygous nonsense…”
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Wernicke's encephalopathy after glucose infusion by KOGUCHI, Ken, NAKATSUJI, Yuji, ABE, Kazuo, SAKODA, Saburo

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Modulation of astrocyte proliferation by cyclin-dependent kinase inhibitor p27(Kip1) by Koguchi, Ken, Nakatsuji, Yuji, Nakayama, Kei-Ichi, Sakoda, Saburo

“…We previously demonstrated that type 1 astrocytes exhibited homotypic cell contact-dependent inhibition of proliferation with increased expression of…”
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Modulation of astrocyte proliferation by cyclin‐dependent kinase inhibitor p27 Kip1 by Koguchi, Ken, Nakatsuji, Yuji, Nakayama, Kei‐Ichi, Sakoda, Saburo

“…Abstract We previously demonstrated that type 1 astrocytes exhibited homotypic cell contact‐dependent inhibition of proliferation with increased expression of…”
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