Search Results - "Kofuji, Kaori"
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Identification of lysine methylation in the core GTPase domain by GoMADScan
Published in PloS one (07-08-2019)“…RAS is the founding member of a superfamily of GTPases and regulates signaling pathways involved in cellular growth control. While recent studies have shown…”
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Correction: Identification of lysine methylation in the core GTPase domain by GoMADScan
Published in PloS one (22-10-2019)“…[This corrects the article DOI: 10.1371/journal.pone.0219436.]…”
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IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma
Published in Nature cell biology (01-08-2019)“…In many cancers, high proliferation rates correlate with elevation of rRNA and tRNA levels, and nucleolar hypertrophy. However, the underlying mechanisms…”
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A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion
Published in Biochemical and biophysical research communications (23-07-2024)“…In animal cells, vacuoles are absent, but can be induced by diseases and drugs. While phosphoinositides are critical for membrane trafficking, their role in…”
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CBIO-12. GTP METABOLIC SWITCH LEADS TO NUCLEOLAR TRANSFORMATION AND MALIGNANT GROWTH OF GLIOBLASTOMA
Published in Neuro-oncology (Charlottesville, Va.) (06-11-2017)“…Nucleolar mass is frequently increased in malignant cells, pointing to a prominent role for aberrant rRNA transcription in highly anabolic cells. ATP and GTP,…”
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