Search Results - "Kofler, D M"

Adenosine receptor A2a blockade by caffeine increases IFN-gamma production in Th1 cells from patients with rheumatoid arthritis by Gloyer, L, Golumba-Nagy, V, Meyer, A, Yan, S, Schiller, J, Breuninger, M, Jochimsen, D, Kofler, D M

“…Studies indicate that caffeine uptake may be a risk factor for rheumatoid arthritis (RA), but a definitive link between caffeine consumption and RA has not…”
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Engagement of the B-cell antigen receptor (BCR) allows efficient transduction of ZAP-70-positive primary B-CLL cells by recombinant adeno-associated virus (rAAV) vectors by KOFLER, D. M, BÜNING, H, MAYR, C, BUND, D, BAUMERT, J, HALLEK, M, WENDTNER, C-M

“…Engagement of the B-cell antigen receptor (BCR) by crosslinking of the surface immunoglobulin (sIg) homodimer was studied for recombinant adeno-associated…”
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Phase 1b trial of atacicept, a recombinant protein binding BLyS and APRIL, in patients with chronic lymphocytic leukemia by Kofler, D M, Gawlik, B B, Elter, T, Gianella-Borradori, A, Wendtner, C-M, Hallek, M

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The Potential of Gene Transfer into Primary B-CLL Cells Using Recombinant Virus Vectors by Wendtner, C-M, Kofler, DM, Mayr, C, Bund, D, Hallek, M

“…Despite recent advances, chronic lymphocytic leukemia (CLL) as the most common leukemia remains a largely incurable disease. Modern treatment options include…”
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Current status of immunotherapy in B cell malignancies by Kofler, D M, Mayr, C, Wendtner, C-M

“…Conventional treatment of hematologic malignancies mainly consists of chemotherapeutic agents or a combination of both, chemotherapy and monoclonal antibodies…”
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Gene transfer preferentially selects MHC class I positive tumour cells and enhances tumour immunogenicity by HACKER, Ulrich T, SCHILDHAUER, Ines, BARROSO, Margarita Céspedes, KOFLER, David M, GERNER, Franz M, MYSLIWIETZ, Josef, BUENING, Hildegard, HALLEK, Michael, KING, Susan B. S

“…The modulated expression of MHC class I on tumour tissue is well documented. Although the effect of MHC class I expression on the tumorigenicity and…”
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Phase 1 b trial of atacicept, a recombinant protein binding BLyS and APRIL, in patients with chronic lymphocytic leukemia by KOFLER, D. M, GAWLIK, B. B, ELTER, T, GIANELLA-BORRADORI, A, WENDTNER, C.-M, HALLEK, M

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Abatacept inhibits inflammation and onset of rheumatoid arthritis in individuals at high risk (ARIAA): a randomised, international, multicentre, double-blind, placebo-controlled trial by Rech, Juergen, Tascilar, Koray, Hagen, Melanie, Kleyer, Arnd, Manger, Bernhard, Schoenau, Verena, Hueber, Axel J, Kleinert, Stefan, Baraliakos, Xenofon, Braun, Jürgen, Kiltz, Uta, Fleck, Martin, Rubbert-Roth, Andrea, Kofler, David M, Behrens, Frank, Feuchtenberger, Martin, Zaenker, Michael, Voll, Reinhard, Venhoff, Nils, Thiel, Jens, Glaser, Cornelia, Feist, Eugen, Burmester, Gerd R, Karberg, Kirsten, Strunk, Johannes, Cañete, Juan D, Senolt, Ladislav, Filkova, Maria, Naredo, Esperanza, Largo, Raquel, Krönke, Gerhard, D'Agostino, Maria-Antonietta, Østergaard, Mikkel, Schett, Georg

“…Individuals with anti-citrullinated protein antibodies (ACPAs) and subclinical inflammatory changes in joints are at high risk of developing rheumatoid…”
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Chromosomal translocations are associated with poor prognosis in chronic lymphocytic leukemia by Mayr, Christine, Speicher, Michael R., Kofler, David M., Buhmann, Raymund, Strehl, John, Busch, Raymonde, Hallek, Michael, Wendtner, Clemens-Martin

“…In chronic lymphocytic leukemia (CLL), chromosomes usually evade detailed cytogenetic analyses because cells poorly respond to the traditionally used set of…”
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A phase Ib trial of atacicept (TACI-Ig) to neutralize APRIL and BLyS in patients with refractory or relapsed B-cell chronic lymphocytic leukemia (B-CLL) by Kofler, D. M., Elter, T., Gianella-Borradori, A., Busby, S., Wendtner, C. M., Hallek, M.

“…Abstract only 3029 Background: B-CLL cells are resistant to apoptosis and thus exhibit prolonged survival and accumulation in vivo. Exogenously added soluble…”
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Efficacy of Ranolazine for Treatment of Coronary Microvascular Dysfunction—A Systematic Review and Meta-analysis of Randomized Trials by Kofler, Thomas, Hess, Stefanie, Moccetti, Federico, Pepine, Carl J., Attinger, Adrian, Wolfrum, Mathias, Toggweiler, Stefan, Kobza, Richard, Cuculi, Florim, Bossard, Matthias

“…Coronary microvascular dysfunction (CMD) is a common cause of angina and exercise intolerance in patients without obstructive coronary artery disease. The…”
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In vitro selection of viral vectors with modified tropism: the adeno-associated virus display by Perabo, Luca, Büning, Hildegard, Kofler, David M, Ried, Martin U, Girod, Anne, Wendtner, Clemens M, Enssle, Jörg, Hallek, Michael

“…Improving the efficiency and specificity of gene vectors is critical for the success of gene therapy. In an effort to generate viral mutants with controlled…”
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High incidence of new translocations in B-CLL detected by CD40L-enhanced cytogenetics (CEC): A new prognostic marker for infavorable survival outcome in patients with B-CLL by Mayr, C., Schoch, C., Kofler, D. M., Busch, R., Hallek, M., Wendtner, C.-M.

“…Abstract only…”
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High incidence of new translocations in B-CLL detected by CD40L-enhanced cytogenetics (CEC): A new prognostic marker for infavorable survival outcome in patients with B-CLL by Mayr, C., Schoch, C., Kofler, D. M., Busch, R., Hallek, M., Wendtner, C.-M.

“…Abstract only…”
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Green Fluorescent Protein-Tagged Adeno-Associated Virus Particles Allow the Study of Cytosolic and Nuclear Trafficking by LUX, Kerstin, GOERLITZ, Nico, BÜNING, Hildegard, SCHLEMMINGER, Stefanie, PERABO, Luca, GOLDNAU, Daniela, ENDELL, Jan, LEIKE, Kristin, KOFLER, David M, FINKE, Stefan, HALLEK, Michael

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Engagement of the B-cell antigen receptor vectors by Kofler, D M, Buning, H, Mayr, C, Bund, D, Baumert, J, Hallek, M, Wendtner, C-M

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Five Hundred Cases of Robotic Totally Endoscopic Coronary Artery Bypass Grafting: Predictors of Success and Safety by Bonaros, Nikolaos, MD, Schachner, Thomas, MD, Lehr, Eric, MD, Kofler, Markus, MD, Wiedemann, Dominik, MD, Hong, Patricia, Wehman, Brody, MD, Zimrin, David, MD, Vesely, Mark K., MD, Friedrich, Guy, MD, Bonatti, Johannes, MD

“…Background Robotic technology has enabled totally endoscopic coronary artery bypass (TECAB) grafting. Little information is available on factors associated…”
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Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes by Mayr, Christine, Bund, Dagmar, Schlee, Martin, Moosmann, Andreas, Kofler, David M., Hallek, Michael, Wendtner, Clemens-Martin

“…Fibromodulin (FMOD) was shown to be highly overexpressed in chronic lymphocytic leukemia (CLL) cells compared with normal B lymphocytes by gene expression…”
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Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis by Irwin, David J, Dr, Grossman, Murray, MD, Weintraub, Daniel, MD, Hurtig, Howard I, MD, Duda, John E, MD, Xie, Sharon X, PhD, Lee, Edward B, MD, Van Deerlin, Vivianna M, MD, Lopez, Oscar L, MD, Kofler, Julia K, MD, Nelson, Peter T, MD, Jicha, Gregory A, MD, Woltjer, Randy, MD, Quinn, Joseph F, MD, Kaye, Jeffery, MD, Leverenz, James B, MD, Tsuang, Debby, MD, Longfellow, Katelan, MD, Yearout, Dora, BS, Kukull, Walter, PhD, Keene, C Dirk, MD, Montine, Thomas J, MD, Zabetian, Cyrus P, MD, Trojanowski, John Q, MD

“…Summary Background Great heterogeneity exists in survival and the interval between onset of motor symptoms and dementia symptoms across synucleinopathies. We…”
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MDM2 is recognized as a tumor-associated antigen in chronic lymphocytic leukemia by CD8 + autologous T lymphocytes by Mayr, Christine, Bund, Dagmar, Schlee, Martin, Bamberger, Martina, Kofler, David M., Hallek, Michael, Wendtner, Clemens-Martin

“…Tumor-associated antigens (TAA) are the basis for antigen-specific immunotherapy. The human homolog of the murine double-minute 2 oncoprotein (MDM2) is a…”
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