Search Results - "Koenen, Tim B."

Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice by Gerrits, Han, van Ingen Schenau, Dorette S., Bakker, Nicole E.C., van Disseldorp, Ad J.M., Strik, Ankie, Hermens, Laura S., Koenen, Tim B., Krajnc-Franken, Magda A.M., Gossen, Jan A.

“…CXCR7 is a G‐protein coupled receptor that was recently deorphanized and shown to have SDF1 and I‐TAC as high affinity ligands. Here we describe the…”
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Hyperglycemia Activates Caspase-1 and TXNIP-Mediated IL-1β Transcription in Human Adipose Tissue by KOENEN, Tim B, STIENSTRA, Rinke, VAN TITS, Lambertus J, DE GRAAF, Jacqueline, STALENHOEF, Anton F. H, JOOSTEN, Leo A. B, TACK, Cees J, NETEA, Mihai G

“…OBJECTIVE Obesity is characterized by elevated levels of proinflammatory cytokines, including interleukin (IL)-1β, that contribute to the development of…”
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Treatment with Anakinra Improves Disposition Index But Not Insulin Sensitivity in Nondiabetic Subjects with the Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study by van Asseldonk, Edwin J. P, Stienstra, Rinke, Koenen, Tim B, Joosten, Leo A. B, Netea, Mihai G, Tack, Cees J

“…Context: Obesity induces low-grade inflammation that may promote the development of insulin resistance. IL-1 is one of the key inflammatory factors. Objective:…”
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The Inflammasome and Caspase-1 Activation: A New Mechanism Underlying Increased Inflammatory Activity in Human Visceral Adipose Tissue by Koenen, Tim B, Stienstra, Rinke, van Tits, Lambertus J, Joosten, Leo A. B, van Velzen, Jeroen F, Hijmans, Anneke, Pol, Jillis A, van der Vliet, J. A, Netea, Mihai G, Tack, Cees J, Stalenhoef, Anton F. H, de Graaf, Jacqueline

“…The immune competent abdominal adipose tissue, either stored viscerally [visceral adipose tissue (VAT)] or sc [sc adipose tissue (SAT)], has been identified as…”
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The Effect of the Interleukin-1 Cytokine Family Members IL-1F6 and IL-1F8 on Adipocyte Differentiation by Asseldonk, Edwin J.P., Stienstra, Rinke, Koenen, Tim B., Tits, Lambertus J.H., Joosten, Leo A.B., Tack, Cees J., Netea, Mihai G.

“…Obesity is characterized by chronic low‐grade inflammation originating from expanding adipose tissue. In the present study, we examined the adipogenic…”
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Adiponectin multimer distribution in patients with familial combined hyperlipidemia by Koenen, Tim B., van Tits, Lambertus J.H., Holewijn, Suzanne, Lemmers, Heidi L.M., den Heijer, Martin, Stalenhoef, Anton F.H., de Graaf, Jacqueline

“…Adiponectin is secreted from adipocytes in different multimers, of which the high molecular weight (HMW) form is supposed to mediate favorable metabolic and…”
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Pioglitazone Treatment Enlarges Subcutaneous Adipocytes in Insulin-Resistant Patients by Koenen, Tim B., Tack, Cees J., Kroese, Jeanne Margot, Hermus, Ad R., Sweep, Fred C. G., van der Laak, Jeroen, Stalenhoef, Anton F. H., de Graaf, Jacqueline, van Tits, Lambertus J. H., Stienstra, Rinke

“…Context: Obesity-related insulin resistance is associated with an increase in adipocyte size. In rodent models, treatment with the insulin-sensitizers…”
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Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1[beta] transcription m human adipose tissue by Koenen, Tim B, Stienstra, Rinke, van Tits, Lambertus J, de Graaf, Jacqueline, Stalenhoef, Anton F.H, Joosten, Leo A.B, Tack, Cees J, Netea, Mihai G

“…OBJECTIVE--Obesity is characterized by elevated levels of proinflammatory cytokines, including interleukin (IL)-1[beta], that contribute to the development of…”
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Hyperglycemia Activates Caspase-1 and TXNIP-Mediated IL-1[Beta] Transcription in Human Adipose Tissue by Koenen, Tim B, Stienstra, Rinke, van Tits, Lambertus J, de Graaf, Jacqueline, Stalenhoef, Anton F H, Joosten, Leo A B, Tack, Cees J, Netea, Mihai G

“…Obesity is characterized by elevated levels of proinflammatory cytokines, including interleukin (IL)-1[beta], that contribute to the development of insulin…”
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Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1β transcription m human adipose tissue by Koenen, Tim B, Stienstra, Rinke, van Tits, Lambertus J, de Graaf, Jacqueline, Stalenhoef, Anton F.H, Joosten, Leo A.B, Tack, Cees J, Netea, Mihai G

“…OBJECTIVE--Obesity is characterized by elevated levels of proinflammatory cytokines, including interleukin (IL)-1β, that contribute to the development of…”
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PS1 - 1. TLR-3 is highly expressed in human adipocytes, but deficiency of TLR3 does not protect against obesity-induced inflammation and insulin resistance in mice by Ballak, Dov B., van Asseldonk, Edwin J.P., van Diepen, Janna A., Koenen, Tim B., Jansen, Henry J., Joosten, Leo A.B., Netea, Mihai G., Tack, Cees J., Stienstra, Rinke

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PS15 - 76. The Toll like receptor 3 in adipose tissue determines local inflammation by van Asseldonk, Edwin J.P., Stienstra, Rinke, Koenen, Tim B., Jansen, Henrique J., Netea, Mihai G., Tack, Cees J.

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Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1beta transcription in human adipose tissue by Koenen, Tim B, Stienstra, Rinke, van Tits, Lambertus J, de Graaf, Jacqueline, Stalenhoef, Anton F H, Joosten, Leo A B, Tack, Cees J, Netea, Mihai G

“…Obesity is characterized by elevated levels of proinflammatory cytokines, including interleukin (IL)-1β, that contribute to the development of insulin…”
Get full text