Search Results - "Koeller, Kevin"

Human Papillomavirus Episome Stability Is Reduced by Aphidicolin and Controlled by DNA Damage Response Pathways by Edwards, Terri G, Helmus, Michael J, Koeller, Kevin, Bashkin, James K, Fisher, Chris

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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DNA damage repair genes controlling human papillomavirus (HPV) episome levels under conditions of stability and extreme instability by Edwards, Terri G, Vidmar, Thomas J, Koeller, Kevin, Bashkin, James K, Fisher, Chris

“…DNA damage response (DDR) genes and pathways controlling the stability of HPV episomal DNA are reported here. We set out to understand the mechanism by which a…”
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β-Alanine and N-terminal cationic substituents affect polyamide-DNA binding by Liu, Beibei, Wang, Shuo, Aston, Karl, Koeller, Kevin J, Kermani, Shahrzad Fanny Hakami, Castañeda, Carlos H, Scuderi, M José, Luo, Rensheng, Bashkin, James K, Wilson, W David

“…Minor-groove binding hairpin polyamides (PAs) bind specific DNA sequences. Synthetic modifications can improve PA-DNA binding affinity and include flexible…”
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Interactions of two large antiviral polyamides with the long control region of HPV16 by Vasilieva, Elena, Niederschulte, Jacquelyn, Song, Yang, Harris, George Davis, Koeller, Kevin J., Liao, Puhong, Bashkin, James K., Dupureur, Cynthia M.

“…PA1 and PA25 are large hairpin polyamides that are effective in nearly eliminating HPV16 episomes (DNA) in cell culture, and PA25 has broad spectrum activity…”
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Binding studies of a large antiviral polyamide to a natural HPV sequence by He, Gaofei, Vasilieva, Elena, Harris, George Davis, Koeller, Kevin J., Bashkin, James K., Dupureur, Cynthia M.

“…PA1 is a large hairpin polyamide (dImPyPy-β-PyPyPy-γ-PyPy-β-PyPyPyPy-β-Ta; Py = pyrrole, Im = imidazole, β = beta alanine) that targets the sequence…”
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Modulation of DNA-polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics by Wang, Shuo, Aston, Karl, Koeller, Kevin J, Harris, Jr, G Davis, Rath, Nigam P, Bashkin, James K, Wilson, W David

“…Hairpin polyamides (PAs) are an important class of sequence-specific DNA minor groove binders, and frequently employ a flexible motif, β-alanine (β), to reduce…”
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Fluorescence assay of polyamide–DNA interactions by Dupureur, Cynthia M., Bashkin, James K., Aston, Karl, Koeller, Kevin J., Gaston, Kimberly R., He, Gaofei

“…Polyamides (PAs) are distamycin-type ligands of DNA that bind the minor groove and are capable of sequence selective recognition. This capability provides a…”
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Promoter scanning of the human COX-2 gene with 8-ring polyamides: Unexpected weakening of polyamide–DNA binding and selectivity by replacing an internal N-Me-pyrrole with β-alanine by Bashkin, James K., Aston, Karl, Ramos, Joseph P., Koeller, Kevin J., Nanjunda, Rupesh, He, Gaofei, Dupureur, Cynthia M., David Wilson, W.

“…Rules for polyamide–DNA recognition have proved invaluable for the design of sequence-selective DNA binding agents in cell-free systems. However, these rules…”
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134 Large antiviral polyamide-DNA interactions by Vasilieva, Elena, Song, Yang, Koeller, Kevin J., Davis Harris, G., Bashkin, James K., Dupureur, Cynthia M.

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HPV episome levels are potently decreased by pyrrole–imidazole polyamides by Edwards, Terri G., Koeller, Kevin J., Slomczynska, Urszula, Fok, Kam, Helmus, Michael, Bashkin, James K., Fisher, Chris

“…Human papillomavirus (HPV) causes cervical cancer and other hyperproliferative diseases. There currently are no approved antiviral drugs for HPV that directly…”
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Towards the development of a safe, metal-catalyzed aerobic oxidation of 2-acetyl thiophene by Koeller, Kevin J., Miller, William H., Walker, Daniel P.

“…[Display omitted] Thiophene-2-carbonyl chloride (TCC) is a key raw material in the manufacture of active ingredients for agriculture. A new 3-step process for…”
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A New Process To Prepare Thiophene-2-Carbonyl Chloride, a Key Raw Material in the Synthesis of Tioxazafen, Utilizing a Catalytic Liquid Phase Aerobic Oxidation Reaction by Walker, Daniel P., Koeller, Kevin J., Miller, William H., Graham, Charles R., Harris, G. Davis, Nigudkar, Swati, Klemm, George H., Li, Wensheng

“…Thiophene-2-carbonyl chloride (TCC) is the key raw material in the preparation of tioxazafen, a proprietary seed treatment that was being developed by Bayer AG…”
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Three step, one-pot process to prepare thiophene-2-carbonyl chloride (TCC), a key raw material in the manufacture of tioxazafen (Nemastrike®) by Walker, Daniel P., Graham, Charles R., Miller, William H., Koeller, Kevin J.

“…[Display omitted] •Thiophene-2-carbonyl chloride (TCC) can be prepared in three steps from CSI.•TCC can be prepared without the need of an expensive oxidation…”
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Development of a Practical Process for the Large-Scale Preparation of the Chiral Pyridyl-Backbone for the Crabtree/Pfaltz-Type Iridium Complex Used in the Industrial Production of the Novel Fungicide Inpyrfluxam by Jones, Michelle, Harris, Dave, Struble, Justin, Hayes, Michael, Koeller, Kevin, Chepiga Özgün, Kathryn, Schirmer, Heiko, Heinrich, Jens, Baechle, Florian, Goudedranche, Sebastien, Schotes, Christoph

“…Herein, we report the development activities leading to an efficient process for the large-scale production of the key intermediate to a crabtree/pfaltz-type…”
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The synthesis, structure and properties of diazaphospholes: Reagents and ligands for asymmetric synthesis by De la Cruz, Antonette, Koeller, Kevin J, Rath, Nigam P, Spilling, Christopher D, Vasconcelos, Isabel C.F

“…Reaction of C 2 diamines with PCl 3 and Et 3N in toluene, followed by water or hydrogen sulfide, gave a series of cyclic phosphorous acid diamides…”
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A new process to prepare 3,6-dichloro-2-hydroxybenzoic acid, the penultimate intermediate in the synthesis of herbicide dicamba by Walker, Daniel P., Harris, G. Davis, Carroll, Jeffery N., Boehm, Terri L., McReynolds, Matthew D., Struble, Justin R., van Herpt, Jochem, van Zwieten, Don, Koeller, Kevin J., Bore, Mangesh

“…[Display omitted] •3,6-Dichloro-2-hydroxybenzoic acid (3,6-DCSA) can be prepared in four steps from salicylic acid.•3,6-DCSA can be prepared without the need…”
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DNA Damage Repair Genes Controlling Human Papillomavirus by Edwards, Terri G, Vidmar, Thomas J, Koeller, Kevin, Bashkin, James K, Fisher, Chris

“…DNA damage response (DDR) genes and pathways controlling the stability of HPV episomal DNA are reported here. We set out to understand the mechanism by which a…”
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Reactions of Chiral Phosphorous Acid Diamides: The Asymmetric Synthesis of Chiral .alpha.-Hydroxy Phosphonamides, Phosphonates, and Phosphonic Acids by Blazis, Vincent J, Koeller, Kevin J, Spilling, Christopher D

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Corrigendum to “Fluorescence assay of polyamide–DNA interactions” [Anal. Biochem. 423 (2012) 178–183] by Dupureur, Cynthia M., Bashkin, James K., Aston, Karl, Koeller, Kevin J., Gaston, Kimberly R., He, Gaofei

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Fluorescence Assay of Polyamide-DNA Interactions1 by Dupureur, Cynthia M., Bashkin, James K., Aston, Karl, Koeller, Kevin J., Gaston, Kimberly R., He, Gaofei

“…Polyamides (PA) are distamycin-type ligands of DNA that bind the minor groove and are capable of sequence selective recognition. This capability provides a…”
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