Search Results - "Koelle, Samson J."

Clonal Tracking of Rhesus Macaque Hematopoiesis Highlights a Distinct Lineage Origin for Natural Killer Cells by Wu, Chuanfeng, Li, Brian, Lu, Rong, Koelle, Samson J., Yang, Yanqin, Jares, Alexander, Krouse, Alan E., Metzger, Mark, Liang, Frank, Loré, Karin, Wu, Colin O., Donahue, Robert E., Chen, Irvin S.Y., Weissman, Irving, Dunbar, Cynthia E.

“…Analysis of hematopoietic stem cell function in nonhuman primates provides insights that are relevant for human biology and therapeutic strategies. In this…”
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Quantitative stability of hematopoietic stem and progenitor cell clonal output in rhesus macaques receiving transplants by Koelle, Samson J., Espinoza, Diego A., Wu, Chuanfeng, Xu, Jason, Lu, Rong, Li, Brian, Donahue, Robert E., Dunbar, Cynthia E.

“…Autologous transplantation of hematopoietic stem and progenitor cells lentivirally labeled with unique oligonucleotide barcodes flanked by sequencing primer…”
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Geographic clonal tracking in macaques provides insights into HSPC migration and differentiation by Wu, Chuanfeng, Espinoza, Diego A, Koelle, Samson J, Potter, E Lake, Lu, Rong, Li, Brian, Yang, Di, Fan, Xing, Donahue, Robert E, Roederer, Mario, Dunbar, Cynthia E

“…The geographic distribution of hematopoiesis at a clonal level is of interest in understanding how hematopoietic stem and progenitor cells (HSPCs) and their…”
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Interrogation of clonal tracking data using barcodetrackR by Espinoza, Diego A, Mortlock, Ryland D, Koelle, Samson J, Wu, Chuanfeng, Dunbar, Cynthia E

“…Clonal tracking methods provide quantitative insights into the cellular output of genetically labelled progenitor cells across time and cellular compartments…”
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Clonal expansion and compartmentalized maintenance of rhesus macaque NK cell subsets by Wu, Chuanfeng, Espinoza, Diego A, Koelle, Samson J, Yang, Di, Truitt, Lauren, Schlums, Heinrich, Lafont, Bernard A, Davidson-Moncada, Jan K, Lu, Rong, Kaur, Amitinder, Hammer, Quirin, Li, Brian, Panch, Sandhya, Allan, David A, Donahue, Robert E, Childs, Richard W, Romagnani, Chiara, Bryceson, Yenan T, Dunbar, Cynthia E

“…Natural killer (NK) cells recognize and eliminate infected and malignant cells. Their life histories are poorly understood, particularly in humans, due to lack…”
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Stochastic Modeling of Hematopoietic Stem and Progenitor Cell Barcoding Data from Rhesus Macaques Challenges the Classic Model of Hematopoiesis by Xu, Jason, Koelle, Samson J., Guttorp, Peter, Wu, Chuanfeng, Dunbar, Cynthia E., Abkowitz, Janis L., Minin, Vladimir

“…The classical model of hematopoiesis states that differentiation proceeds from hematopoietic stem cells (HSC) to mature blood cells via specified multipotent…”
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Clonal Tracking of the Geographic Distribution of Hematopoiesis in Nonhuman Primates Provides New Insights into HSPC Migration and Differentiation by Wu, Chuanfeng, Koelle, Samson J, Li, Brian, Espinoza, Diego, Lu, Rong, Krouse, Allen E, Metzger, Mark, Donahue, Robert, Dunbar, Cynthia E.

“…Hematopoietic stem and progenitor cells (HSPC) primarily reside in bone marrow (BM) niches, but are also found in peripheral blood (PB) in small numbers. Large…”
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Clonal Expansion and Long-Term Persistence of Rhesus Macaque NK Cells with an Adaptive Phenotype by Wu, Chuanfeng, Espinoza, Diego A, Koelle, Samson J., Yang, Di, Schlums, Heinrich, Davidson-Moncada, Jan K., Lu, Rong, Kaur, Amitinder, Quirin, Hammer, Li, Brian, Panch, Sandhya R., Donahue, Robert E, Childs, Richard W., Romagnani, Chiara, Bryceson, Yenan, Dunbar, Cynthia E.

“…Natural killer (NK) cells are defined as lymphocytes capable of target cell killing and cytokine production independent of somatic antigen receptor…”
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