Search Results - "Koekkoek, Sebastiaan K.E"

Evolving Models of Pavlovian Conditioning: Cerebellar Cortical Dynamics in Awake Behaving Mice by ten Brinke, Michiel M., Boele, Henk-Jan, Spanke, Jochen K., Potters, Jan-Willem, Kornysheva, Katja, Wulff, Peer, IJpelaar, Anna C.H.G., Koekkoek, Sebastiaan K.E., De Zeeuw, Chris I.

“…Three decades of electrophysiological research on cerebellar cortical activity underlying Pavlovian conditioning have expanded our understanding of motor…”
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Cerebellar Motor Learning Deficits in Medicated and Medication-Free Men with Recent-Onset Schizophrenia by Coesmans, Michael, MD, PhD, Röder, Christian H., MD, Smit, Albertine E., PhD, Koekkoek, Sebastiaan K.E., PhD, De Zeeuw, Chris I., MD, PhD, Frens, Maarten A., PhD, van der Geest, Josef N., PhD

“…Background The notion that cerebellar deficits may underlie clinical symptoms in people with schizophrenia is tested by evaluating 2 forms of cerebellar…”
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Different Purkinje cell pathologies cause specific patterns of progressive gait ataxia in mice by Jaarsma, Dick, Birkisdóttir, Maria B., van Vossen, Randy, Oomen, Demi W.G.D., Akhiyat, Oussama, Vermeij, Wilbert P., Koekkoek, Sebastiaan K.E., De Zeeuw, Chris I., Bosman, Laurens W.J.

“…Gait ataxia is one of the most common and impactful consequences of cerebellar dysfunction. Purkinje cells, the sole output neurons of the cerebellar cortex,…”
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Anatomical pathways involved in generating and sensing rhythmic whisker movements by Bosman, Laurens W J, Houweling, Arthur R, Owens, Cullen B, Tanke, Nouk, Shevchouk, Olesya T, Rahmati, Negah, Teunissen, Wouter H T, Ju, Chiheng, Gong, Wei, Koekkoek, Sebastiaan K E, De Zeeuw, Chris I

“…The rodent whisker system is widely used as a model system for investigating sensorimotor integration, neural mechanisms of complex cognitive tasks, neural…”
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Expression of a Protein Kinase C Inhibitor in Purkinje Cells Blocks Cerebellar LTD and Adaptation of the Vestibulo-Ocular Reflex by De Zeeuw, Chris I., Hansel, Christian, Bian, Feng, Koekkoek, Sebastiaan K.E., van Alphen, Adriaan M., Linden, David J., Oberdick, John

“…Cerebellar long-term depression (LTD) is a model system for neuronal information storage that has an absolute requirement for activation of protein kinase C…”
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Light microscopic and ultrastructural investigation of the dopaminergic innervation of the ventrolateral outgrowth of the rat inferior olive by Toonen, Mariske, van Dijken, Henk, Holstege, Jan C, Ruigrok, Tom J.H, Koekkoek, Sebastiaan K.E, Hawkins, Richard K, Teune, Thea M, v.d. Burg, J, De Zeeuw, Chris I

“…The ventrolateral outgrowth of the inferior olive is involved in the control of compensatory eye movement responses to optokinetic stimuli about the horizontal…”
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Reconstructing human cerebral vasculature in 3D with high frame rate, freehand 2D Doppler ultrasound using optical tracking by Verhoef, Luuk, Soloukey, Sadaf, Mastik, Frits, Generowicz, Bastian S., Vincent, Arnaud J.P.E., Bos, Eelke M., Schouten, Joost W., Dirven, Clemens M.F., de Zeeuw, Chris I., Koekkoek, Sebastiaan K.E., Klein, Stefan, Kruizinga, Pieter

“…Accurate and real-time assessment of brain vascu-lature during neurosurgery is possible using 2D µDoppler ultrasound imaging. In order to view the complete…”
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Swept-3-D Ultrasound Imaging of the Mouse Brain Using a Continuously Moving 1-D-Array-Part I: Doppler Imaging by Generowicz, Bastian S., Dijkhuizen, Stephanie, De Zeeuw, Chris I., Koekkoek, Sebastiaan K. E., Kruizinga, Pieter

“…Volumetric 3-D Doppler ultrasound imaging can be used to investigate large scale blood dynamics outside of the limited view that conventional 2-D power Doppler…”
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Swept-3-D Ultrasound Imaging of the Mouse Brain Using a Continuously Moving 1-D-Array-Part II: Functional Imaging by Generowicz, Bastian S., Dijkhuizen, Stephanie, Bosman, Laurens W. J., De Zeeuw, Chris I., Koekkoek, Sebastiaan K. E., Kruizinga, Pieter

“…Functional ultrasound (fUS) using a 1-D-array transducer normally is insufficient to capture volumetric functional activity due to being restricted to imaging…”
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Functional Ultrasound (fUS) During Awake Brain Surgery: The Clinical Potential of Intra-Operative Functional and Vascular Brain Mapping by Soloukey, Sadaf, Vincent, Arnaud J P E, Satoer, Djaina D, Mastik, Frits, Smits, Marion, Dirven, Clemens M F, Strydis, Christos, Bosch, Johannes G, van der Steen, Antonius F W, De Zeeuw, Chris I, Koekkoek, Sebastiaan K E, Kruizinga, Pieter

“…Oncological neurosurgery relies heavily on making continuous, intra-operative tumor-brain delineations based on image-guidance. Limitations of currently…”
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Cerebellar control of gait and interlimb coordination by Vinueza Veloz, María Fernanda, Zhou, Kuikui, Bosman, Laurens W. J., Potters, Jan-Willem, Negrello, Mario, Seepers, Robert M., Strydis, Christos, Koekkoek, Sebastiaan K. E., De Zeeuw, Chris I.

“…Synaptic and intrinsic processing in Purkinje cells, interneurons and granule cells of the cerebellar cortex have been shown to underlie various relatively…”
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Axonal sprouting and formation of terminals in the adult cerebellum during associative motor learning by Boele, Henk-Jan, Koekkoek, Sebastiaan K E, De Zeeuw, Chris I, Ruigrok, Tom J H

“…Plastic changes in the efficacy of synapses are widely regarded to represent mechanisms underlying memory formation. So far, evidence for learning-dependent,…”
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Delay eyeblink conditioning performance and brain-wide c-Fos expression in male and female mice by Oyaga, Maria Roa, Serra, Ines, Kurup, Devika, Koekkoek, Sebastiaan K E, Badura, Aleksandra

“…Delay eyeblink conditioning has been extensively used to study associative learning and the cerebellar circuits underlying this task have been largely…”
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Cerebellar cortex and cerebellar nuclei are concomitantly activated during eyeblink conditioning: a 7T fMRI study in humans by Thürling, Markus, Kahl, Fabian, Maderwald, Stefan, Stefanescu, Roxana M, Schlamann, Marc, Boele, Henk-Jan, De Zeeuw, Chris I, Diedrichsen, Jörn, Ladd, Mark E, Koekkoek, Sebastiaan K E, Timmann, Dagmar

“…There are controversies whether learning of conditioned eyeblink responses primarily takes place within the cerebellar cortex, the interposed nuclei, or both…”
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Performance in eyeblink conditioning is age and sex dependent by Löwgren, Karolina, Bååth, Rasmus, Rasmussen, Anders, Boele, Henk-Jan, Koekkoek, Sebastiaan K E, De Zeeuw, Chris I, Hesslow, Germund

“…A growing body of evidence suggests that the cerebellum is involved in both cognition and language. Abnormal cerebellar development may contribute to…”
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Functional imaging of the exposed brain by Soloukey, Sadaf, Vincent, Arnaud J P E, Smits, Marion, De Zeeuw, Chris I, Koekkoek, Sebastiaan K E, Dirven, Clemens M F, Kruizinga, Pieter

“…When the brain is exposed, such as after a craniotomy in neurosurgical procedures, we are provided with the unique opportunity for real-time imaging of brain…”
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Modulation of 7 T fMRI Signal in the Cerebellar Cortex and Nuclei During Acquisition, Extinction, and Reacquisition of Conditioned Eyeblink Responses by Ernst, Thomas M., Thürling, Markus, Müller, Sarah, Kahl, Fabian, Maderwald, Stefan, Schlamann, Marc, Boele, Henk‐Jan, Koekkoek, Sebastiaan K. E., Diedrichsen, Jörn, De Zeeuw, Chris I., Ladd, Mark E., Timmann, Dagmar

“…Classical delay eyeblink conditioning is likely the most commonly used paradigm to study cerebellar learning. As yet, few studies have focused on extinction…”
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Cerebellar potentiation and learning a whisker-based object localization task with a time response window by Rahmati, Negah, Owens, Cullen B, Bosman, Laurens W J, Spanke, Jochen K, Lindeman, Sander, Gong, Wei, Potters, Jan-Willem, Romano, Vincenzo, Voges, Kai, Moscato, Letizia, Koekkoek, Sebastiaan K E, Negrello, Mario, De Zeeuw, Chris I

“…Whisker-based object localization requires activation and plasticity of somatosensory and motor cortex. These parts of the cerebral cortex receive strong…”
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Origin of Vestibular Dysfunction in Usher Syndrome Type 1B by Sun, John C., van Alphen, Adriaan M., Wagenaar, Mariette, Huygen, Patrick, Hoogenraad, Casper C., Hasson, Tama, Koekkoek, Sebastiaan K.E., Bohne, Barbara A., De Zeeuw, Chris I.

“…It is still debated to what extent the vestibular deficits in Usher patients are due to either central vestibulocerebellar or peripheral vestibular problems…”
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Encoding of whisker input by cerebellar Purkinje cells by Bosman, Laurens W. J., Koekkoek, Sebastiaan K. E., Shapiro, Joël, Rijken, Bianca F. M., Zandstra, Froukje, Van Der Ende, Barry, Owens, Cullen B., Potters, Jan‐Willem, De Gruijl, Jornt R., Ruigrok, Tom J. H., De Zeeuw, Chris I.

“…The cerebellar cortex is crucial for sensorimotor integration. Sensorimotor inputs converge on cerebellar Purkinje cells via two afferent pathways: the…”
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