Search Results - "Koehler, Heike"
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Volatile emissions from Mycobacterium avium subsp. paratuberculosis mirror bacterial growth and enable distinction of different strains
Published in PloS one (08-10-2013)“…Control of paratuberculosis in livestock is hampered by the low sensitivity of established direct and indirect diagnostic methods. Like other bacteria,…”
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2
A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells
Published in Molecular cancer therapeutics (01-10-2004)“…The trisubstituted acridine derivative BRACO-19 has been designed to interact with and stabilize the quadruplex DNA structures that can be formed by folding of…”
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3
Management of the calving pen is a crucial factor for paratuberculosis control in large dairy herds
Published in Journal of dairy science (01-05-2016)“…Improvement of hygiene and herd management to reduce the contact of calves with adult cow feces to prevent new infections is one of the basic strategies to…”
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Acid-base variables in acute and chronic form of nontuberculous mycobacterial infection in growing goats experimentally inoculated with Mycobacterium avium subsp. hominissuis or Mycobacterium avium subsp. paratuberculosis
Published in PloS one (14-12-2020)“…In current literature, data assessing the acid-base equilibrium in animals and humans during bacterial infection are rare. This study aimed to evaluate…”
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5
CD28 costimulation overcomes transforming growth factor-β-mediated repression of proliferation of redirected human CD4+ and CD8+ T cells in an antitumor cell attack
Published in Cancer research (Chicago, Ill.) (01-03-2007)“…The T-cell-mediated antitumor immune response is frequently repressed in the tumor environment by an immunologic barrier, the predominant mediators of which…”
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6
Development and evaluation of two multi-antigen serological assays for the diagnosis of bovine tuberculosis in cattle
Published in Journal of microbiological methods (01-10-2018)“…There is currently an increased interest in the use of serological approaches in combination with traditional cell-mediated immunity-based techniques to…”
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Challenge Dose Titration in a Mycobacterium bovis Infection Model in Goats
Published in International journal of molecular sciences (10-09-2024)“…Goats are natural hosts of , and affected herds can be the cause of significant economic losses. Similarites in disease course and lesions of infections in…”
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Mycobacterium avium subsp. Paratuberculosis in Different Environmental Samples from a Dairy Goat Barn-Implications for Sampling Strategies for Paratuberculosis Diagnostic and Prevention
Published in Animals (Basel) (18-05-2023)“…Environmental samples are often used to classify the paratuberculosis status of cattle herds. The disease is caused by subsp. (MAP), predominantly through oral…”
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Variation in the Performance of Different Batches of Two Mycobacterium avium Subspecies paratuberculosis Antibody ELISAs Used for Pooled Milk Samples
Published in Animals (Basel) (12-02-2022)“…Regionally, the monitoring of paratuberculosis at the herd level is performed by the detection of specific antibodies in pooled milk samples by ELISA. The…”
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Mycobacteriosis in Various Pet and Wild Birds from Germany: Pathological Findings, Coinfections, and Characterization of Causative Mycobacteria
Published in Microbiology spectrum (31-08-2022)“…A total of 50 birds diagnosed with mycobacteriosis were examined for pathomorphological lesions, coinfections, and causative agents. Mycobacterial species were…”
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Comparative analysis of volatile organic compounds for the classification and identification of mycobacterial species
Published in PloS one (20-03-2018)“…Species of Mycobacteriaceae cause serious zoonotic diseases in mammals, for example tuberculosis in humans, dogs, parrots, and elephants (caused by…”
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Safety and Immunogenicity of Recombinant Bacille Calmette-Guérin Strain VPM1002 and Its Derivatives in a Goat Model
Published in International journal of molecular sciences (14-03-2023)“…A more effective vaccine against tuberculosis than (BCG) is urgently needed. BCG derived recombinant VPM1002 has been found to be more efficacious and safer…”
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Vaccine-Induced Subcutaneous Granulomas in Goats Reflect Differences in Host-Mycobacterium Interactions between BCG- and Recombinant BCG-Derivative Vaccines
Published in International journal of molecular sciences (20-09-2022)“…Tuberculous granulomas are highly dynamic structures reflecting the complex host-mycobacterium interactions. The objective of this study was to compare…”
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Analysis of Colostrum and Udder Skin Swabs from a Dairy Goat Herd in Germany regarding the Occurrence of Mycobacterium avium Subsp. paratuberculosis
Published in Animals (Basel) (11-07-2022)“…Oral intake of Mycobacterium avium subspecies paratuberculosis (MAP) in first days of life is considered to be the main route of infection for…”
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Characterization of a caprine model for the subclinical initial phase of Mycobacterium avium subsp. paratuberculosis infection
Published in BMC veterinary research (24-03-2015)“…BACKGROUND: Paratuberculosis caused by Mycobacterium avium subsp. paratuberculosis (MAP) is difficult to control due to a long phase of clinically non-apparent…”
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In Vivo Volatile Organic Compound Signatures of Mycobacterium avium subsp. paratuberculosis
Published in PloS one (27-04-2015)“…Mycobacterium avium ssp. paratuberculosis (MAP) is the causative agent of a chronic enteric disease of ruminants. Available diagnostic tests are complex and…”
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Evaluation of associations between genotypes of Mycobacterium avium subsp. paratuberculsis and presence of intestinal lesions characteristic of paratuberculosis
Published in Veterinary microbiology (01-03-2017)“…•Weak indications for different virulence among MAP field isolates of cattle type.•No association between combined genotypes and presence or absence of…”
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Suspicion of Mycobacterium avium subsp. paratuberculosis Transmission between Cattle and Wild-Living Red Deer (Cervus elaphus) by Multitarget Genotyping
Published in Applied and Environmental Microbiology (01-02-2012)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis
Published in International journal of medical microbiology (01-10-2014)“…Abstract Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of paratuberculosis (Johne's disease [JD]), a chronic granulomatous…”
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Molecular Diversity of Mycobacterium avium subsp. paratuberculosis in Four Dairy Goat Herds from Thuringia (Germany)
Published in Animals (Basel) (01-11-2023)“…This study investigated the intra- and inter-herd diversity of Mycobacterium avium subsp. paratuberculosis (MAP) isolates from four goat herds in Thuringia…”
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