Aminomethylation of Uracil and 6-Methyluracil by 3,4-dimethoxyphenylethylamine and Tetrahydroisoquinoline Derivatives
The Mannich reactions of uracil and 6-methyluracil with homoveratrylamine and 1-aryltetrahydroisoquinolines in EtOH and dioxane were studied. 5-[(2-Hydroxymethyl)-4,5-dimethoxyphenylethylamino)methyl]-6-methylpyrimidine-2,4(1 H , 3 H )-dione was formed in EtOH in addition to the usual products (in d...
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Published in: | Chemistry of natural compounds Vol. 59; no. 2; pp. 331 - 335 |
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Main Authors: | , , , , |
Format: | Journal Article |
Language: | English |
Published: |
New York
Springer US
01-03-2023
Springer Springer Nature B.V |
Subjects: | |
Online Access: | Get full text |
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Summary: | The Mannich reactions of uracil and 6-methyluracil with homoveratrylamine and 1-aryltetrahydroisoquinolines in EtOH and dioxane were studied. 5-[(2-Hydroxymethyl)-4,5-dimethoxyphenylethylamino)methyl]-6-methylpyrimidine-2,4(1
H
, 3
H
)-dione was formed in EtOH in addition to the usual products (in dioxane). |
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ISSN: | 0009-3130 1573-8388 |
DOI: | 10.1007/s10600-023-03987-9 |