Search Results - "Kodet, John"
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Synthesis of Indole Analogues of the Natural Schweinfurthins
Published in Journal of organic chemistry (20-09-2013)“…An interest in the schweinfurthins, natural stilbenes with significant antiproliferative activity, has prompted efforts to prepare a set of indole analogues…”
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Journal Article -
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Exploration of Cascade Cyclizations Terminated by Tandem Aromatic Substitution: Total Synthesis of (+)-Schweinfurthin A
Published in Journal of organic chemistry (04-02-2011)“…The termination of epoxide-initiated cascade cyclizations with a range of “protected” phenols is described. When the protecting group can be lost as a…”
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3
Synthesis and structure activity relationships of schweinfurthin indoles
Published in Bioorganic & medicinal chemistry (15-04-2014)“…As part of a program to explore the biological activity of analogues of the natural schweinfurthins, a set of compounds has been prepared where an indole…”
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Journal Article -
4
Electrophilic aromatic prenylation via cascade cyclization
Published in Tetrahedron (04-11-2013)“…To gain access to prenylated hexahydroxanthenes, tandem cascade cyclization–electrophilic aromatic substitution reactions have been studied on substrates…”
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Structural analogues of schweinfurthin F: Probing the steric, electronic, and hydrophobic properties of the D-ring substructure
Published in Bioorganic & medicinal chemistry (15-02-2010)“…Synthesis of a set of schweinfurthin analogues varied in the D-ring alkyl substituent and stilbene moiety has been accomplished, and the activity of these…”
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Journal Article -
6
Relevance of the C-5 position to schweinfurthin induced cytotoxicity
Published in Bioorganic & medicinal chemistry (15-12-2011)“…The schweinfurthins are an intriguing group of anti-proliferative agents that display low nanomolar activities against several cell types, including the…”
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Journal Article -
7
A new graphical version of STROTAB: The analysis and fitting of singlet–triplet spectra of asymmetric top molecules in the prolate or oblate limits
Published in Computer physics communications (01-05-2007)“…The original version of STROTAB has been modified to run under Microsoft Windows using the C++ programming language. The new version takes full advantage of…”
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Studies on heteroaromatic schweinfurthin analogues
Published 01-01-2010“…Natural products are a rich source of lead compounds for treatment of cancer as well as other diseases. Researchers at the National Cancer Institute, as part…”
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Dissertation -
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The isotopic dependence of axes switching in thiophosgene induced by electronic excitation
Published in Journal of molecular spectroscopy (01-08-2005)Get full text
Journal Article -
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The isotopic dependence of axes switching in thiophosgene induced by A ˜ 1 A 2 ( n π ∗ ) ← X ˜ 1 A 1 electronic excitation
Published in Journal of molecular spectroscopy (2005)“…A line-by-line rotational analysis of a selected group of bands in the high-resolution A ˜ 1 A 2 ( n π ∗ ) ← X ˜ 1 A 1 fluorescence excitation spectrum has…”
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Journal Article