Search Results - "Kodali, Goutham"

Coexistence of Different Electron-Transfer Mechanisms in the DNA Repair Process by Photolyase by Lee, Wook, Kodali, Goutham, Stanley, Robert J., Matsika, Spiridoula

“…DNA photolyase has been the topic of extensive studies due to its important role of repairing photodamaged DNA, and its unique feature of using light as an…”
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De novo synthetic biliprotein design, assembly and excitation energy transfer by Mancini, Joshua A., Sheehan, Molly, Kodali, Goutham, Chow, Brian Y., Bryant, Donald A., Dutton, P. Leslie, Moser, Christopher C.

“…Bilins are linear tetrapyrrole chromophores with a wide range of visible and near-visible light absorption and emission properties. These properties are tuned…”
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Design and engineering of water-soluble light-harvesting protein maquettes by Kodali, Goutham, Mancini, Joshua A, Solomon, Lee A, Episova, Tatiana V, Roach, Nicholas, Hobbs, Christopher J, Wagner, Pawel, Mass, Olga A, Aravindu, Kunche, Barnsley, Jonathan E, Gordon, Keith C, Officer, David L, Dutton, P Leslie, Moser, Christopher C

“…Natural selection in photosynthesis has engineered tetrapyrrole based, nanometer scale, light harvesting and energy capture in light-induced charge separation…”
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Constructing a man-made c-type cytochrome maquette in vivo : electron transfer, oxygen transport and conversion to a photoactive light harvesting maquette by Anderson, J L Ross, Armstrong, Craig T, Kodali, Goutham, Lichtenstein, Bruce R, Watkins, Daniel W, Mancini, Joshua A, Boyle, Aimee L, Farid, Tammer A, Crump, Matthew P, Moser, Christopher C, Dutton, P Leslie

“…The successful use of man-made proteins to advance synthetic biology requires both the fabrication of functional artificial proteins in a living environment,…”
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Multi-step excitation energy transfer engineered in genetic fusions of natural and synthetic light-harvesting proteins by Mancini, Joshua A., Kodali, Goutham, Jiang, Jianbing, Reddy, Kanumuri Ramesh, Lindsey, Jonathan S., Bryant, Donald A., Dutton, P. Leslie, Moser, Christopher C.

“…Synthetic proteins designed and constructed from first principles with minimal reference to the sequence of any natural protein have proven robust and…”
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Charge Redistribution in Oxidized and Semiquinone E. coli DNA Photolyase upon Photoexcitation: Stark Spectroscopy Reveals a Rationale for the Position of Trp382 by Kodali, Goutham, Siddiqui, Salim U, Stanley, Robert J

“…The electronic structure of the two lowest excited electronic states of FAD and FADH• in folate-depleted E. coli DNA photolyase (PLOX and PLSQ, respectively)…”
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2-Aminopurine Excited State Electronic Structure Measured by Stark Spectroscopy by Kodali, Goutham, Kistler, Kurt A, Matsika, Spiridoula, Stanley, Robert J

“…2-Aminopurine (2AP) is an adenine analogue that has a high fluorescence quantum yield. Its fluorescence yield decreases significantly when the base is…”
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Screening for Novel Fluorescent Nucleobase Analogues Using Computational and Experimental Methods: 2‑Amino-6-chloro-8-vinylpurine (2A6Cl8VP) as a Case Study by Russel, Nadim Shahriar, Kodali, Goutham, Stanley, Robert J., Narayanan, Madhavan

“…Novel fluorescent nucleic acid base analogues (FBAs) with improved optical properties are needed in a variety of biological applications…”
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Screening for novel fluorescent nucleobase analogs (FBAs) using computational and experimental methods ‐ 2‐amino‐8‐vinylpurine (2A8VP), as a Case study by Russel, Nadim S., Kodali, Goutham, Stanley, Robert, Narayanan, Madhavan

“…Fluorescent nucleobase analogs (FBAs) are molecular reporters that are structurally similar to naturally occurring nucleotides but that have significantly…”
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Tailorable Tetrahelical Bundles as a Toolkit for Redox Studies by Solomon, Lee A., Witten, Joshua, Kodali, Goutham, Moser, Christopher C., Dutton, P. Leslie

“…Oxidoreductases have evolved over millions of years to perform a variety of metabolic tasks crucial for life. Understanding how these tasks are engineered…”
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Strong Coupling of Localized Surface Plasmons to Excitons in Light-Harvesting Complexes by Tsargorodska, Anna, Cartron, Michaël L, Vasilev, Cvetelin, Kodali, Goutham, Mass, Olga A, Baumberg, Jeremy J, Dutton, P. Leslie, Hunter, C. Neil, Törmä, Päivi, Leggett, Graham J

“…Gold nanostructure arrays exhibit surface plasmon resonances that split after attaching light harvesting complexes 1 and 2 (LH1 and LH2) from purple bacteria…”
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Engineering the Assembly of Heme Cofactors in Man-Made Proteins by Solomon, Lee A, Kodali, Goutham, Moser, Christopher C, Dutton, P. Leslie

“…Timely ligation of one or more chemical cofactors at preselected locations in proteins is a critical preamble for catalysis in many natural enzymes, including…”
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Elementary tetrahelical protein design for diverse oxidoreductase functions by Farid, Tammer A, Kodali, Goutham, Solomon, Lee A, Lichtenstein, Bruce R, Sheehan, Molly M, Fry, Bryan A, Bialas, Chris, Ennist, Nathan M, Siedlecki, Jessica A, Zhao, Zhenyu, Stetz, Matthew A, Valentine, Kathleen G, Anderson, J L Ross, Wand, A Joshua, Discher, Bohdana M, Moser, Christopher C, Dutton, P Leslie

“…Assembled helical maquettes have been used to mimic basic oxidoreductase activities, but the requisite design symmetry limited advanced functions. Construction…”
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Magnetically Sensitive Radical Photochemistry of Non-natural Flavoproteins by Zollitsch, Tilo M, Jarocha, Lauren E, Bialas, Chris, Henbest, Kevin B, Kodali, Goutham, Dutton, P. Leslie, Moser, Christopher C, Timmel, Christiane R, Hore, P. J, Mackenzie, Stuart R

“…It is a remarkable fact that ∼50 μT magnetic fields can alter the rates and yields of certain free-radical reactions and that such effects might be the basis…”
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Excited-State Electronic Properties of 6-Methylisoxanthopterin (6-MI): An Experimental and Theoretical Study by Kodali, Goutham, Narayanan, Madhavan, Stanley, Robert J

“…6-Methylisoxanthopterin (6-MI) is a pteridine-based guanine analog that has a red-shifted absorption and high fluorescence quantum yield. Its Watson–Crick…”
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Engineering an Artificial Flavoprotein Magnetosensor by Bialas, Chris, Jarocha, Lauren E, Henbest, Kevin B, Zollitsch, Tilo M, Kodali, Goutham, Timmel, Christiane R, Mackenzie, Stuart R, Dutton, P. Leslie, Moser, Christopher C, Hore, P. J

“…Migratory birds use the Earth’s magnetic field as a source of navigational information. This light-dependent magnetic compass is thought to be mediated by…”
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Rational Construction of Compact de Novo-Designed Biliverdin-Binding Proteins by Sheehan, Molly M, Magaraci, Michael S, Kuznetsov, Ivan A, Mancini, Joshua A, Kodali, Goutham, Moser, Christopher C, Dutton, P. Leslie, Chow, Brian Y

“…We report the rational construction of de novo-designed biliverdin-binding proteins by first principles of protein design, informed by energy minimization…”
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Overlapping Electronic States with Nearly Parallel Transition Dipole Moments in Reduced Anionic Flavin Can Distort Photobiological Dynamics by Kodali, Goutham, Siddiqui, M. Salim U, Stanley, Robert J

“…Chromophoric biomolecules are exploited as reporters of a diverse set of phenomena, acting as internal distance monitors, environment and redox sensors, and…”
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An Ethenoadenine FAD Analog Accelerates UV Dimer Repair by DNA Photolyase by Narayanan, Madhavan, Singh, Vijay R., Kodali, Goutham, Moravcevic, Katarina, Stanley, Robert J.

“…Reduced anionic flavin adenine dinucleotide (FADH−) is the critical cofactor in DNA photolyase (PL) for the repair of cyclobutane pyrimidine dimers (CPD) in…”
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The De Novo Engineering of Artificial Flavoproteins by Bialas, Chris, Kodali, Goutham, Moser, Christopher C., Dutton, P. Leslie

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