Search Results - "Koda, Joy E"
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Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies
Published in Proceedings of the National Academy of Sciences - PNAS (20-05-2008)“…Body weight is regulated by complex neurohormonal interactions between endocrine signals of long-term adiposity (e.g., leptin, a hypothalamic signal) and…”
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Enhanced Weight Loss With Pramlintide/Metreleptin: An Integrated Neurohormonal Approach to Obesity Pharmacotherapy
Published in Obesity (Silver Spring, Md.) (01-09-2009)“…The neurohormonal control of body weight involves a complex interplay between long‐term adiposity signals (e.g., leptin), and short‐term satiation signals…”
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Interaction of Leptin and Amylin in the Long-term Maintenance of Weight Loss in Diet-induced Obese Rats
Published in Obesity (Silver Spring, Md.) (01-01-2010)“…We have previously shown that combined amylin + leptin agonism elicits synergistic weight loss in diet-induced obese (DIO) rats. Here, we assessed the…”
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Hyperamylinemia, Hyperinsulinemia, and Insulin Resistance in Genetically Obese LA/N-cp Rats
Published in Hypertension (Dallas, Tex. 1979) (01-01-1992)“…The experimental evidence supporting a direct role for hyperinsulinemia as a cause of insulin resistance remains equivocal. Amylin, an islet β-cell peptide…”
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Serum levels and biochemical characteristics of cancer-associated antigen CA-549, a circulating breast cancer marker
Published in Cancer research (Chicago, Ill.) (15-11-1987)“…CA-549 is a circulating breast cancer-associated antigen that reacts with monoclonal antibody BC4E 549. Biochemical characterization of CA-549 revealed that it…”
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Development of sensitive immunoassays to detect amylin and amylin-like peptides in unextracted plasma
Published in Clinical chemistry (Baltimore, Md.) (01-04-1996)“…Amylin is a 37-amino-acid polypeptide synthesized in and secreted from pancreatic beta cells along with insulin. Its biological actions include the slowing and…”
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Amylin concentrations and glucose control
Published in The Lancet (British edition) (09-05-1992)Get more information
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Preclinical pharmacology of pramlintide in the rat: Comparisons with human and rat amylin
Published in Drug development research (01-04-1996)“…The pancreatic β‐cell hormone, amylin, is absent or reduced in individuals with type I diabetes mellitus and in many insulin‐treated patients with type II…”
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Molecular physiology of amylin
Published in Journal of cellular biochemistry (1994)“…Amylin is a 37-amino acid peptide first isolated, purified, and characterized from the amyloid deposits in the pancrease of type 2 diabetics. It is synthesized…”
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Gestational diabetes mellitus is associated with an increase in the total concentration of amylin molecules
Published in Diabetes care (01-04-1998)Get full text
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