Search Results - "Kock, Matthias"
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Linear diterpenes from the marine brown alga Bifurcaria bifurcata: a chemical perspective
Published in Phytochemistry reviews (01-09-2013)“…This article will give a complete overview of linear diterpenes isolated from the brown alga Bifurcaria bifurcata . For this purpose all published acyclic…”
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Is Enantiomer Assignment Possible by NMR Spectroscopy Using Residual Dipolar Couplings from Chiral Nonracemic Alignment Media?-A Critical Assessment
Published in Angewandte Chemie International Edition (13-08-2012)“…Insensitive towards inversion: Can residual dipolar couplings (RDCs) and other anisotropic NMR observables be used to determine absolute configuration? A…”
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3
Further eleganolone-derived diterpenes from the brown alga Bifurcaria bifurcata
Published in Tetrahedron letters (11-04-2012)“…Four new diterpenes (1–4) together with six known members of this family were isolated from the brown alga Bifurcaria bifurcata collected off the coast near…”
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4
Tracking of fast moving neuronal vesicles with ageladine A
Published in Biochemical and biophysical research communications (19-11-2010)“…► Vesicle tracking in cultured hippocampal neurons is shown using the alkaloid ageladine A derived marine sponges. ► Ageladine A is pH sensitive and…”
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Bayesian Inference Applied to NMR-Based Configurational Assignments by Floating Chirality Distance Geometry Calculations
Published in Journal of the American Chemical Society (20-04-2022)“…Using NMR data, the assignment of the correct 3D configuration and conformation to unknown natural products is of pivotal importance in pharmaceutical and…”
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NMR-Based Configurational Assignments of Natural Products: How Floating Chirality Distance Geometry Calculations Simplify Gambling with 2 N–1 Diastereomers
Published in Journal of natural products (Washington, D.C.) (22-07-2022)“…Using NMR data, the assignment of the correct 3D configuration and conformation to unknown natural products is of pivotal importance in pharmaceutical and…”
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7
Formyleleganolone and bibifuran, two metabolites from the brown alga Bifurcaria bifurcata
Published in Phytochemistry letters (01-12-2012)“…[Display omitted] ► Isolation of two new diterpenoids from the brown alga Bifurcaria bifurcata. ► Structure elucidation of the two new diterpenoids by 1D and…”
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NMR-Based Configurational Assignments of Natural Products: Gibbs Sampling and Bayesian Inference Using Floating Chirality Distance Geometry Calculations
Published in Marine drugs (22-12-2021)“…Floating chirality restrained distance geometry (fc-rDG) calculations are used to directly evolve structures from NMR data such as NOE-derived intramolecular…”
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Model-Free Approach for the Configurational Analysis of Marine Natural Products
Published in Marine drugs (21-05-2021)“…The NMR-based configurational analysis of complex marine natural products is still not a routine task. Different NMR parameters are used for the assignment of…”
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Incorporation of 4J-HMBC and NOE Data into Computer-Assisted Structure Elucidation with WebCocon
Published in Molecules (Basel, Switzerland) (11-08-2021)“…Over the past decades, different software programs have been developed for the Computer-Assisted Structure Elucidation (CASE) with NMR data using with various…”
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Structural Assignment of Tetrabromostyloguanidine: Does the Relative Configuration of the Palau'amines Need Revision?
Published in Angewandte Chemie International Edition (01-01-2007)“…Products of the Caribbean: The palau'amine derivative tetrabromostyloguanidine 1 was isolated from the sponge Stylissa caribica and the elucidation of its…”
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The Advanced Floating Chirality Distance Geometry Approach-How Anisotropic NMR Parameters Can Support the Determination of the Relative Configuration of Natural Products
Published in Marine drugs (24-06-2020)“…The configurational analysis of complex natural products by NMR spectroscopy is still a challenging task. The assignment of the relative configuration is…”
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13
Hybrid Pyrrole–Imidazole Alkaloids from the Sponge Agelas sceptrum
Published in Journal of natural products (Washington, D.C.) (26-02-2016)“…A chemical investigation of the tropical sponge Agelas sceptrum from Plana Cays (Bahamas) led to the isolation of two hybrid pyrrole–imidazole alkaloids…”
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14
Anti-Infective and Antiviral Activity of Valinomycin and Its Analogues from a Sea Cucumber-Associated Bacterium, Streptomyces sp. SV 21
Published in Marine drugs (02-02-2021)“…The manuscript investigated the isolation, characterization and anti-infective potential of valinomycin ( ), streptodepsipeptide P11A ( ), streptodepsipeptide…”
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Enantioselective Total Syntheses of (−)-Palau’amine, (−)-Axinellamines, and (−)-Massadines
Published in Journal of the American Chemical Society (21-09-2011)“…Dimeric pyrrole–imidazole alkaloids represent a rich and topologically unique class of marine natural products. This full account will follow the progression…”
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Bioplastics in the Sea: Rapid In-Vitro Evaluation of Degradability and Persistence at Natural Temperatures
Published in Frontiers in Marine Science (23-06-2022)“…The progressive substitution of petroleum-based polymers, such as polyethylene, polyvinylchloride, or polyethylene terephtalate, by so-called bioplastics…”
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Stylissadines A and B: The First Tetrameric Pyrrole−Imidazole Alkaloids
Published in Organic letters (12-10-2006)“…Pyrrole−imidazole alkaloids are widely distributed in marine sponges of the orders Halichondrida and Agelasida. Chemical investigation of the Caribbean sponge…”
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Structure Elucidation and in Vitro Toxicity of New Azaspiracids Isolated from the Marine Dinoflagellate Azadinium poporum
Published in Marine drugs (30-10-2015)“…Two strains of Azadinium poporum, one from the Korean West coast and the other from the North Sea, were mass cultured for isolation of new azaspiracids…”
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Stylissamides E and F, Cyclic Heptapeptides from the Caribbean Sponge Stylissa caribica
Published in Journal of natural products (Washington, D.C.) (23-04-2010)“…In addition to the four known stylissamides, A (1), B (2), C, and D, two new cyclic heptapeptides, stylissamides E (3) and F (4), were isolated from the…”
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The marine sponge Agelas citrina as a source of the new pyrrole-imidazole alkaloids citrinamines A-D and N-methylagelongine
Published in Beilstein journal of organic chemistry (29-10-2015)“…The chemical investigation of the Caribbean sponge Agelas citrina revealed four new pyrrole-imidazole alkaloids (PIAs), the citrinamines A-D (1-4) and the…”
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