Search Results - "Kock, Josef"

Generation of covalently closed circular DNA of hepatitis B viruses via intracellular recycling is regulated in a virus specific manner by Köck, Josef, Rösler, Christine, Zhang, Jing-Jing, Blum, Hubert E, Nassal, Michael, Thoma, Christian

“…Persistence of hepatitis B virus (HBV) infection requires covalently closed circular (ccc)DNA formation and amplification, which can occur via intracellular…”
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Cultivation of HepG2.2.15 on Cytodex-3: Higher yield of hepatitis B virus and less subviral particles compared to conventional culture methods by Lupberger, Joachim, Mund, Andreas, Kock, Josef, Hildt, Eberhard

“…Several novel systems are available to study human hepatitis B virus (HBV) replication in cell culture demanding for efficient cell culture based systems for…”
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Inhibitory effect of adefovir and lamivudine on the initiation of hepatitis B virus infection in primary tupaia hepatocytes by Köck, Josef, Baumert, Thomas F., Delaney, William E., Blum, Hubert E., von Weizsäcker, Fritz

“…Adefovir dipivoxil and lamivudine are two safe and efficacious drugs licensed for the treatment of chronic hepatitis B virus (HBV) infection. Both drugs…”
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Central Role of a Serine Phosphorylation Site within Duck Hepatitis B Virus Core Protein for Capsid Trafficking and Genome Release by Köck, Josef, Kann, Michael, Pütz, Gerhard, Blum, Hubert E., von Weizsäcker, Fritz

“…Viral nucleocapsids compartmentalize and protect viral genomes during assembly while they mediate targeted genome release during viral infection. This dual…”
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Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H by Kock, Josef, Blum, Hubert E

“…Department of Medicine II, University of Freiburg, Freiburg, Germany Correspondence Josef Köck josefkoeck{at}web.de Hepatitis B virus (HBV) is a DNA virus that…”
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Virus replication and virion export in X-deficient hepatitis B virus transgenic mice by Reifenberg, Kurt, Nusser, Petra, Lohler, Jurgen, Spindler, Gabriele, Kuhn, Christa, von Weizsacker, Fritz, Kock, Josef

“…Central Laboratory Animal Facility of the Johannes Gutenberg–University of Mainz, Obere Zahlbacherstr. 67 – Hochhaus am Augustusplatz, D-55101 Mainz, Germany 1…”
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Hepatitis B Virus Nucleocapsids Formed by Carboxy-Terminally Mutated Core Proteins Contain Spliced Viral Genomes but Lack Full-Size DNA by KÖCK, Josef, NASSAL, Michael, DERES, Karl, BLUM, Hubert E, VON WEIZSÄCKER, Fritz

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Comment on "Inhibition of hepatitis B virus replication by APOBEC3G" by Rösler, Christine, Köck, Josef, Malim, Michael H, Blum, Hubert E, von Weizsäcker, Fritz

“…The cytidine deaminase APOBEC3G (A3G) was recently identified as a natural resistance gene that restricts efficient propagation of human immunodeficiency virus…”
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Efficient Infection of Primary Tupaia Hepatocytes with Purified Human and Woolly Monkey Hepatitis B Virus by Koeck, J, Nassal, M, MacNelly, S, Baumert, T F, Blum, HE, von Weizsaecker, F

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Human hepatitis B virus production in avian cells is characterized by enhanced RNA splicing and the presence of capsids containing shortened genomes by Köck, Josef, Rösler, Christine, Zhang, Jingjing, Blum, Hubert E, Nassal, Michael, Thoma, Christian

“…Experimental studies on hepatitis B virus (HBV) replication are commonly done with human hepatoma cells to reflect the natural species and tissue tropism of…”
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Suppression of hepatitis B virus replication in Tupaia hepatocytes by tumor necrosis factor alpha of Tupaia belangeri by Xu, Yang, Köck, Josef, Lu, Yinping, Yang, Dongliang, Lu, Mengji, Zhao, Xiping

“…Abstract Recently, Tupaia belangeri was used to study the full replication cycle of hepatitis B virus (HBV) in the primary hepatocyte cultures. Thus, the…”
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The tupaia model for the study of hepatitis B virus: direct infection and HBV genome transduction of primary tupaia hepatocytes by von Weizsäcker, Fritz, Köck, Josef, MacNelly, Sabine, Ren, Shaotang, Blum, Hubert E, Nassal, Michael

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Duck hepatitis B virus nucleocapsids formed by N-terminally extended or C-terminally truncated core proteins disintegrate during viral DNA maturation by Kock, J. (University of Freiburg, Freiburg, Germany.), Wieland, S, Blum, H.E, Von Weizsacker, F

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Trypsinogen gene mutations in patients with chronic or recurrent acute pancreatitis by TRUNINGER, Kaspar, KÖCK, Josef, WIRTH, Hans-Peter, MUELLHAUPT, Beat, ARNOLD, Christian, VON WEIZSÄCKER, Fritz, SEIFERT, Burkhardt, AMMANN, Rudolf W, BLUM, Hubert E

“…Three-point mutations (R117H, N211, A16V) within the cationic trypsinogen gene have been identified in patients with hereditary pancreatitis (HP). A genetic…”
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APOBEC-mediated interference with hepadnavirus production by RÖSLER, Christine, KÖCK, Josef, KANN, Michael, MALIM, Michael H, BLUM, Hubert E, BAUMERT, Thomas F, VON WEIZSÄCKER, Fritz

“…APOBEC3G is a cellular cytidine deaminase displaying broad antiretroviral activity. Recently, it was shown that APOBEC3G can also suppress hepatitis B virus…”
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Generation of Covalently Closed Circular DNA of Hepatitis B Viruses via Intracellular Recycling Is Regulated in a Virus Specific Manner: e1001082 by Köck, Josef, Rösler, Christine, Zhang, Jing-Jing, Blum, Hubert E, Nassal, Michael, Thoma, Christian

“…Persistence of hepatitis B virus (HBV) infection requires covalently closed circular (ccc)DNA formation and amplification, which can occur via intracellular…”
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Hepatitis B virus mutations associated with fulminant hepatitis induce apoptosis in primary Tupaia hepatocytes by BAUMERT, Thomas F, CHUN YANG, SCHÜRMANN, Peter, KÖCK, Josef, ZIEGLER, Christian, GRÜLLICH, Carsten, NASSAL, Michael, LIANG, T. Jake, BLUM, Hubert E, VON WEIZSÄCKER, Fritz

“…Hepatitis B virus (HBV) core promoter mutations have been implicated in the pathogenesis of fulminant hepatitis B. Due to the limited availability of primary…”
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Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes by Dandri, Maura, Burda, Martin R., Zuckerman, David M., Wursthorn, Karsten, Matschl, Urte, Pollok, Joerg M., Rogiers, Xavier, Gocht, Andreas, Köck, Josef, Blum, Hubert E., Weizsäcker, Fritz von, Petersen, Joerg

“…Transplantation of primary human hepatocytes and establishment of hepatitis B virus (HBV) infection in immunodeficient urokinase plasminogen activator (uPA)…”
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A novel target of hepatitis B virus mutations: splicing of surface RNA by Baumert, Thomas F, Köck, Josef, Blum, Hubert E

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Structure and sequence of the gene for the largest subunit of trypanosomal RNA polymerase III by KÖCK, J, EVERS, R, CORNELISSEN, A. W. C. A

“…As the first step in the analysis of the transcription process in the African trypanosome, Trypanosoma brucei, we have started to characterise the trypanosomal…”
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