Search Results - "Kocić, Gordana"
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Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity
Published in European journal of medicinal chemistry (28-07-2017)“…Xanthine oxidase (XO), a versatile metalloflavoprotein enzyme, catalyzes the oxidative hydroxylation of hypoxanthine and xanthine to uric acid in purine…”
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2
Phthalates leaching from plastic food and pharmaceutical contact materials by FTIR and GC-MS
Published in Environmental science and pollution research international (01-06-2021)“…Phthalates are often used as plasticizers in the production of plastic food contact materials (FCMs) and pharmaceutical contact materials (PCMs), and having in…”
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3
Myt1 kinase inhibitors - Insight into structural features, offering potential frameworks
Published in Chemico-biological interactions (01-03-2024)“…The cell cycle includes two checkpoint arrests allowing to repair of damaged DNA. Many cancer cell lines exhibit weak G1 checkpoint mechanisms relying…”
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4
Ascorbic acid as DNase I inhibitor in prevention of male infertility
Published in Biochemical and biophysical research communications (15-04-2018)“…Apoptotic and/or ROS-induced DNA fragmentation in sperm cells may contribute to the development of male infertility. As the known dietary antioxidant, ascorbic…”
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5
Benzimidazoles as novel deoxyribonuclease I inhibitors
Published in Journal of cellular biochemistry (01-11-2018)“…Inhibitory potential of 19 benzimidazoles against bovine pancreatic deoxyribonuclease I (DNase I) was investigated in vitro. Three compounds inhibited DNase I…”
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6
Maternal age has more pronounced effect on breast milk retinol and β-carotene content than maternal dietary pattern
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-09-2019)“…•Maternal age was strongly correlated with retinol and β-carotene levels in human milk samples.•Maternal age had more pronounced effect on retinol and…”
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7
Synthesis and analysis of 4-oxothiazolidines as potential dual inhibitors of deoxyribonuclease I and xanthine oxidase
Published in Chemico-biological interactions (25-08-2021)“…In this study, seven new 4-oxothiazolidine derivatives were synthesized and assayed, along 7 known derivatives, for inhibitory properties against…”
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8
Oxidative stress and metabolic biomarkers in patients with Psoriasis
Published in Journal of medical biochemistry (01-01-2024)“…Psoriasis is an autoinflammatory disease that affects not only skin but multiple organs thus being associated with many comorbidities. Oxidative stress and…”
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9
Nanoliposome-encapsulated ellagic acid prevents cyclophosphamide-induced rat liver damage
Published in Molecular and cellular biochemistry (01-08-2019)“…In this study, we aimed to evaluate whether the encapsulation of ellagic acid (EA) into nanoliposomes would improve its potential in preventing…”
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10
The Influence of Removable Complete Denture on Pro‐Oxidant Antioxidant Balance and Redox‐Sensitive Inflammation Biomarker NF‐ĸB in the Oral Cavity: An Interventional Follow‐Up Study
Published in Clinical and experimental dental research (01-10-2024)“…ABSTRACT Objectives Oxidative stress, an imbalance between the body's natural antioxidant defenses and the production of reactive oxygen species (ROS), can…”
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Synthesis and DNase I inhibitory properties of some 4‐thiazolidinone derivatives
Published in Journal of cellular biochemistry (01-01-2019)“…Twelve new thiazolidinones were synthesized and, together with 41 previously synthesized thiazolidinones, evaluated for inhibitory activity against…”
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12
Assessment of GC-MS response of selected pesticides in apple matrices related to matrix concentration
Published in Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes (04-05-2019)“…A uniform analyte response is required for GC-MS analysis in order to obtain acceptable quantitative results. The response of pesticides in complex matrices is…”
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13
Sorbent‐excluding sample preparation method for GC–MS pesticide analysis in apple peel
Published in Biomedical chromatography (01-01-2020)“…Apple peel is frequently exposed to pesticides, especially in the last stages of the pesticide treatment practice. For a certain period, peel retains most of…”
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14
Optimization of simultaneous determination of metals in commercial pumpkin seed oils using inductively coupled atomic emission spectrometry
Published in Microchemical journal (01-09-2018)“…In this work, the inductively coupled plasma atomic emission spectrometry (ICP-AES) was developed and validated for determination of 27 metals in nine pumpkin…”
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15
Template-Independent Poly(A)-Tail Decay and RNASEL as Potential Cellular Biomarkers for Prostate Cancer Development
Published in Cancers (29-04-2022)“…The post-transcriptional messenger RNA (mRNA) decay and turnover rate of the template-independent poly(A) tail, localized at the 3'-untranslated region (3'UTR)…”
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16
Exposomic Fingerprint in the Development of Diseases: The Role of Free Radicals and Multiomics
Published in Oxidative medicine and cellular longevity (2022)“…[...]by using a linear regression model, they documented that hypertension, anosmia, ageusia, the O2−level, and the duration at the ICU may be predictors of…”
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Variation in the Phenolic Compounds Profile and Antioxidant Activity in Different Parts of Hawthorn (Crataegus pentagyna Willd.) During Harvest Periods
Published in Polish journal of food and nutrition sciences (18-11-2019)“…Plants of the genus Crataegus , Rosaceae, are widely distributed and have long been used for food and in folk medicine for the treatment of various ailments…”
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18
Selected 4-phenyl hydroxycoumarins: In vitro cytotoxicity, teratogenic effect on zebrafish (Danio rerio) embryos and molecular docking study
Published in Chemico-biological interactions (25-04-2015)“…•The highest cytotoxic activity in MRC5 fibroblasts and A375 melanoma was determined for 7,8-dihydroxy-4-phenyl coumarin.•SAR studies revealed the influence of…”
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Xanthine Oxidase/Dehydrogenase Activity as a Source of Oxidative Stress in Prostate Cancer Tissue
Published in Diagnostics (Basel) (03-09-2020)“…Prostate cancer (PC) is one of the most frequent malignancies. Better biomarkers are constantly wanted, such as those which can help with the prediction of…”
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Deoxyribonuclease I Inhibitory Properties, Molecular Docking and Molecular Dynamics Simulations of 1‐(Pyrrolidin‐2‐yl)propan‐2‐one Derivatives
Published in Chemistry & biodiversity (01-03-2021)“…Deoxyribonuclease I (DNase I) inhibitory properties of two 1‐(pyrrolidin‐2‐yl)propan‐2‐one derivatives were examined in vitro. Determined IC50 values of…”
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