Search Results - "Kochanowsky, Joshua A"

ROP16-mediated activation of STAT6 enhances cyst development of type III Toxoplasma gondii in neurons by Kochanowsky, Joshua A, Chandrasekaran, Sambamurthy, Sanchez, Jacqueline R, Thomas, Kaitlin K, Koshy, Anita A

“…Toxoplasma gondii establishes a long-lived latent infection in the central nervous system (CNS) of its hosts. Reactivation in immunocompromised individuals can…”
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IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii by Chandrasekaran, Sambamurthy, Kochanowsky, Joshua A., Merritt, Emily F., Lagas, Joseph S., Swannigan, Ayesha, Koshy, Anita A.

“…Dogma holds that Toxoplasma gondii persists in neurons because neurons cannot clear intracellular parasites, even with IFN-γ stimulation. As several recent…”
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The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival by Tuladhar, Shraddha, Kochanowsky, Joshua A, Bhaskara, Apoorva, Ghotmi, Yarah, Chandrasekaran, Sambamurthy, Koshy, Anita A

“…Toxoplasma gondii is an intracellular parasite that persistently infects the CNS and that has genetically distinct strains which provoke different acute immune…”
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Toxoplasma type II effector GRA15 has limited influence in vivo by Merritt, Emily F, Kochanowsky, Joshua A, Hervé, Perrine, Watson, Alison A, Koshy, Anita A

“…Toxoplasma gondii is an intracellular parasite that establishes a long-term infection in the brain of many warm-blooded hosts, including humans and rodents…”
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ROP16-Mediated Activation of STAT6 Suppresses Host Cell Reactive Oxygen Species Production, Facilitating Type III Toxoplasma gondii Growth and Survival by Kochanowsky, Joshua A, Thomas, Kaitlin K, Koshy, Anita A

“…Polymorphic effector proteins determine the susceptibility of strains to IFN-γ-mediated clearance mechanisms deployed by murine host cells. However, less is…”
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Toxoplasma gondii by Kochanowsky, Joshua A., Koshy, Anita A.

“…Putting cat lovers on notice: Toxoplasma gondii is here to control your brain…or is it? Kochanowsky and Koshy shine the spotlight on this notorious pathogen…”
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A Single Transcription Factor Drives Toxoplasma gondii Differentiation by Kochanowsky, Joshua A., Koshy, Anita A.

“…Microbes that cause persistent infections (e.g., herpes viruses) do so by switching from fast-growing lytic states to slow-growing latent states. Waldman…”
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Trichomonas vaginalis extracellular vesicles up-regulate and directly transfer adherence factors promoting host cell colonization by Kochanowsky, Joshua A, Mira, Portia M, Elikaee, Samira, Muratore, Katherine, Rai, Anand Kumar, Riestra, Angelica M, Johnson, Patricia J

“…, a common sexually transmitted parasite that colonizes the human urogenital tract, secretes extracellular vesicles (TvEVs) that are taken up by human cells…”
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The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses by Chen, Longfei, Christian, David A, Kochanowsky, Joshua A, Phan, Anthony T, Clark, Joseph T, Wang, Shuai, Berry, Corbett, Oh, Jung, Chen, Xiaoguang, Roos, David S, Beiting, Daniel P, Koshy, Anita A, Hunter, Christopher A

“…The ability of Toxoplasma gondii to inject the rhoptry kinase ROP16 into host cells results in the activation of the transcription factors STAT3 and STAT6, but…”
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The ROP16.sub.III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival by Tuladhar, Shraddha, Kochanowsky, Joshua A, Bhaskara, Apoorva, Ghotmi, Yarah, Chandrasekaran, Sambamurthy, Koshy, Anita A

“…Toxoplasma gondii is an intracellular parasite that persistently infects the CNS and that has genetically distinct strains which provoke different acute immune…”
Get full text