Search Results - "Koch, Stephanie"
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Spinal Circuits for Touch, Pain, and Itch
Published in Annual review of physiology (10-02-2018)“…The exteroceptive somatosensory system is important for reflexive and adaptive behaviors and for the dynamic control of movement in response to external…”
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2
Gate control of mechanical itch by a subpopulation of spinal cord interneurons
Published in Science (American Association for the Advancement of Science) (30-10-2015)“…Light mechanical stimulation of hairy skin can induce a form of itch known as mechanical itch. This itch sensation is normally suppressed by inputs from…”
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A harmonized atlas of mouse spinal cord cell types and their spatial organization
Published in Nature communications (29-09-2021)“…Single-cell RNA sequencing data can unveil the molecular diversity of cell types. Cell type atlases of the mouse spinal cord have been published in recent…”
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4
Activity-dependent development of tactile and nociceptive spinal cord circuits
Published in Annals of the New York Academy of Sciences (01-03-2013)“…Developing brain circuits are shaped by postnatal sensory experience, but little is known about this process at the level of the spinal cord. Here we review…”
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5
RORβ Spinal Interneurons Gate Sensory Transmission during Locomotion to Secure a Fluid Walking Gait
Published in Neuron (Cambridge, Mass.) (20-12-2017)“…Animals depend on sensory feedback from mechanosensory afferents for the dynamic control of movement. This sensory feedback needs to be selectively modulated…”
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Microglial Refinement of A-Fiber Projections in the Postnatal Spinal Cord Dorsal Horn Is Required for Normal Maturation of Dynamic Touch
Published in The Journal of neuroscience (10-01-2024)“…Sensory systems are shaped in postnatal life by the refinement of synaptic connectivity. In the dorsal horn of the spinal cord, somatosensory circuits undergo…”
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Identification of a Spinal Circuit for Light Touch and Fine Motor Control
Published in Cell (29-01-2015)“…Sensory circuits in the dorsal spinal cord integrate and transmit multiple cutaneous sensory modalities including the sense of light touch. Here, we identify a…”
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The selectivity of rostroventral medulla descending control of spinal sensory inputs shifts postnatally from A fibre to C fibre evoked activity
Published in The Journal of physiology (01-04-2014)“…Key points Brainstem descending pathways control the balance of excitation and inhibition in spinal sensory networks. In adult rodents, descending inhibition…”
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Motor task-selective spinal sensorimotor interneurons in mammalian circuits
Published in Current opinion in physiology (01-04-2019)“…•Proprioceptive and cutaneous input are necessary for an adaptive locomotor gait.•Sensory input during locomotion can recruit protective, or corrective…”
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Author Correction: A harmonized atlas of mouse spinal cord cell types and their spatial organization
Published in Nature communications (19-10-2022)Get full text
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11
C-fiber activity-dependent maturation of glycinergic inhibition in the spinal dorsal horn of the postnatal rat
Published in Proceedings of the National Academy of Sciences - PNAS (24-07-2012)“…Sensory circuits are shaped by experience in early postnatal life and in many brain areas late maturation of inhibition drives activity-dependent development…”
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Inhibition downunder: an update from the spinal cord
Published in Current opinion in neurobiology (01-06-2014)“…Highlights • Presynaptic inhibitory synapse formation. • Inhibitory commissural neurons and left–right coordination. • Inhibition and push–pull in motor…”
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Author Correction: A harmonized atlas of mouse spinal cord cell types and their spatial organization
Published in Nature communications (18-02-2022)Get full text
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14
Effects of a Short Messaging Service–Based Skin Cancer Prevention Campaign in Adolescents
Published in American journal of preventive medicine (01-11-2014)“…Background Skin cancer prevention emphasizes early adoption and practice of sun protection behaviors. Adolescence represents a high-risk period for ultraviolet…”
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Observations of reproductive behaviors in the Critically Endangered bowmouth guitarfish Rhina ancylostoma
Published in Endangered species research (28-03-2024)“…Wedgefishes, family Rhinidae, are collectively identified as one of the most threatened groups of chondrichthyan fishes globally by the International Union for…”
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A shallow scattering layer structures the energy seascape of an open ocean predator
Published in Science advances (04-10-2023)“…Large predators frequent the open ocean where subsurface light drives visually based trophic interactions. However, we lack knowledge on how predators achieve…”
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Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa
Published in Journal of medicinal chemistry (01-11-2007)“…Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo…”
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Assessing anthropogenic disturbances to develop buffer zones for shorebirds using a stopover site
Published in The Journal of wildlife management (01-01-2014)“…Anthropogenic disturbance can degrade the quality of stopover sites for migratory shorebirds. We investigated the potential effects of pedestrian traffic and…”
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Vegetable protein intake is associated with lower gallbladder disease risk: findings from the Women's Health Initiative prospective cohort
Published in Preventive medicine (01-07-2016)“…Abstract Objective. This study aimed to measure associations between gallbladder disease and protein intake patterns, separated by quantity and type (vegetable…”
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Midazolam Potentiates Nociceptive Behavior, Sensitizes Cutaneous Reflexes, and Is Devoid of Sedative Action in Neonatal Rats
Published in Anesthesiology (Philadelphia) (2008)“…The significant postnatal maturation of gamma-aminobutyric acid signaling in the developing brain is likely to have important implications for infant pain…”
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