Search Results - "Koch, Osvaldo R."
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Oxidative stress and antioxidant defenses in ethanol-induced cell injury
Published in Molecular Aspects of Medicine (01-02-2004)“…Although in the past several mechanisms and factors have been proposed to be responsible for alcoholic liver disease (ALD), at present the involvement of…”
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Abrogation of hepatocyte apoptosis and early appearance of liver dysplasia in ethanol-fed p53-deficient mice
Published in Biochemical and biophysical research communications (03-12-2004)“…Ethanol consumption represents a major risk factor for cancer development, and a significant fraction of hepatocarcinomas arises in alcoholic liver cirrhosis…”
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Role of the life span determinant P66 in ethanol-induced liver damage
Published in Laboratory investigation (01-07-2008)“…Mice lacking the 66 kDa isoform of the adapter molecule shcA (p66(shcA)) display increased resistance to oxidative stress and delayed aging. In cultured cell…”
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Cardiac mitochondrial function and tissue remodelling are improved by a non-antihypertensive dose of enalapril in spontaneously hypertensive rats
Published in Free radical research (01-01-2009)“…Renal and cardiac benefits of renin-angiotensin system inhibition exceed blood pressure (BP) reduction and seem to involve mitochondrial function. It has been…”
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Liver necrosis induced by acute intraperitoneal ethanol administration in aged rats
Published in Free radical research (01-03-2002)“…It is generally agreed that the deleterious pathophysiological effects of ethanol are caused, at least partially by an increase in free radical production…”
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Prolonged phenobarbital pretreatment abolishes the early oxidative stress component induced in the liver by acute lindane intoxication
Published in Toxicology letters (10-04-2000)“…Lindane administration to rats (60 mg/kg b.w.) led to an enhancement in the oxidative stress status of the liver at 4 h after treatment, characterized by…”
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Regression of morphological alterations and oxidative stress-related parameters after acute lindane-induced hepatotoxicity in rats
Published in Toxicology (Amsterdam) (28-02-1997)“…Changes in rat liver oxidative stress-related parameters, morphological alterations, as well as circulating and tissue levels of lindane were studied 1–7 days…”
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Lindane-induced oxidative stress. I. Time course of changes in hepatic microsomal parameters, antioxidant enzymes, lipid peroxidative indices and morphological characteristics
Published in Xenobiotica (1988)“…1. Lindane (60 mg/kg) administered orally to rats increased liver cytochrome P-450 content and superoxide radical (O2-.) generation 24 h after treatment, while…”
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Role of the life span determinant P66shcA in ethanol-induced liver damage
Published in Laboratory investigation (01-07-2008)“…Mice lacking the 66 kDa isoform of the adapter molecule shcA (p66 shcA ) display increased resistance to oxidative stress and delayed aging. In cultured cell…”
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The Effect of Acute and Chronic Ethanol Administration on Prolactin Secretion in Male Rats
Published in Journal of andrology (01-09-1982)“…The effect of acute and chronic administration of ethanol on prolactin secretion in male rats was investigated under basal conditions and after the…”
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Effects of dietary protein on the liver of rats in experimental chronic alcoholism
Published in The Journal of nutrition (01-04-1968)Get more information
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Increased chemiluminescence and superoxide production in the liver of chronically ethanol-treated rats
Published in Archives of biochemistry and biophysics (01-12-1983)“…Rats fed ethanol (1.74 +/- 0.12 g/day/100 g body wt for 12 weeks) showed a 45% increased microsomal production of O-2 (2.23 +/- 0.14 nmol/min/mg protein) and a…”
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Increased biliary glutathione disulfide release in chronically ethanol-treated rats
Published in FEBS letters (15-07-1979)Get full text
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Chemiluminescence of the in situ rat liver after acute ethanol intoxication--effect of (+)-cyanidanol-3
Published in Biochemical pharmacology (15-09-1983)Get more information
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Recovery from chronic hepatic lesions in rats fed alcohol and a solid super diet12
Published in The American journal of clinical nutrition (01-09-1972)“…When rats consume for prolonged periods large amounts of a sweetened alcohol mixture, the hepatic lesions, i.e., fatty changes, fibrosis, and cirrhosis, which…”
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Biochemical lesions of liver mitochondria from rats after chronic alcohol consumption
Published in Experimental and molecular pathology (01-10-1977)Get more information
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Effects of quinestrol on hepatic function in the rat
Published in Contraception (Stoneham) (01-09-1978)“…Hepatic function in female rats given 200 microgram of quinestrol every 15 days for up to 210 days was studied. Prolonged treatment with quinestrol affected…”
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Recovery from chronic hepatic lesions in rats fed alcohol and a solid super diet
Published in The American journal of clinical nutrition (01-09-1972)Get full text
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