Search Results - "Kocemba‐Pilarczyk, Kinga A."
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Teaching “Biochemistry with Elements of Chemistry” in the COVID‐19 pandemic
Published in Biochemistry and molecular biology education (01-05-2023)“…The purpose of the presented article is to evaluate the students' perception of the online teaching educational model as a part of the “Biochemistry with…”
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Does the absence of SARS‐CoV‐2 specific genes always exclude the infection? How to interpret RT‐PCR results?—The scenario of interactive online workshop
Published in Biochemistry and molecular biology education (01-07-2021)“…The aim of this online workshop is to familiarize biomedical faculties students with the principle of RT‐PCR method. The following assumption is made, students…”
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Application of case study to introduce medical students to molecular biology techniques used in HIV diagnostics
Published in Biochemistry and molecular biology education (01-05-2019)“…Diagnostic molecular biology is a fast developing discipline of laboratory medicine widely used in numerous medical branches such as oncology, hematology,…”
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Caffeic Acid Targets AMPK Signaling and Regulates Tricarboxylic Acid Cycle Anaplerosis while Metformin Downregulates HIF-1α-Induced Glycolytic Enzymes in Human Cervical Squamous Cell Carcinoma Lines
Published in Nutrients (28-06-2018)“…The small molecules, natural antioxidant Caffeic Acid (trans-3,4-Dihydroxycinnamic acid CA) and anti-diabetic drug Metformin (Met), activate 5′-adenosine…”
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Regularization and grouping -omics data by GCA method: A transcriptomic case
Published in PloS one (01-11-2018)“…The paper presents the application of Grade Correspondence Analysis (GCA) and Grade Correspondence Cluster Analysis (GCCA) for ordering and grouping -omics…”
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Expression of Alternative Splice Variants of 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase-4 in Normoxic and Hypoxic Melanoma Cells
Published in International journal of molecular sciences (17-08-2021)“…Cancer-specific isoenzyme of phosphofructokinase II ( ), as our previous research has shown, may be one of the most important enzymes contributing to the…”
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The influence of PFK-II overexpression on neuroblastoma patients' survival may be dependent on the particular isoenzyme expressed, PFKFB3 or PFKFB4
Published in Cancer cell international (14-11-2019)“…During cancer progression metabolic reprogramming is observed in parallel to the alternation in transcriptional profiles of malignant cells. Recent studies…”
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Analysis of Malignant Melanoma Cell Lines Exposed to Hypoxia Reveals the Importance of PFKFB4 Overexpression for Disease Progression
Published in Anticancer research (01-12-2018)“…Most melanomas develop in hypoxic conditions. Since hypoxia via HIF-1 induces glycolysis, a process essential for malignant melanoma growth/survival, the goal…”
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Molecular biology techniques in real life - case study introducing medical students to QF-PCR technique used in medical diagnostics
Published in Folia medica cracoviensia (30-07-2023)“…QF-PCR is a widely used molecular biology method. To name just a few of its uses, it is considered to be useful in paternity tests, identification tests or…”
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The Epigenetic Modifier 5-Aza-2-deoxycytidine Triggers the Expression of CD146 Gene in Prostate Cancer Cells
Published in Anticancer research (01-05-2019)“…During cancer progression cells undergo epithelial-to-mesenchymal transition (EMT). Although EMT is a complex process, recently, it has been reported that…”
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Targeting the hypoxia pathway in malignant plasma cells by using 17-allylamino-17-demethoxygeldanamycin
Published in Acta biochimica polonica (01-01-2018)Get full text
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α-Lipoic acid increases the viability of nephrocytes and elevates sulfane sulfur level in plasma of patients with chronic kidney disease
Published in Folia medica cracoviensia (30-06-2024)“…Kidney diseases are a major global health problem affecting millions of people. Despite this, there is as yet no effective drug therapy improving outcome in…”
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Aberrant promoter methylation may be responsible for the control of CD146 (MCAM) gene expression during breast cancer progression
Published in Acta biochimica Polonica (11-12-2019)“…The CD146 (also known as MCAM, MUC-18, Mel-CAM) was initially reported in 1987, as a protein crucial for the invasiveness of malignant melanoma. Recently, it…”
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