Search Results - "Kocbach, Anette"
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Phthalate exposure and allergic diseases: Review of epidemiological and experimental evidence
Published in Environment international (01-06-2020)“…[Display omitted] •The relationship between phthalate exposure and allergic diseases is reviewed.•Epidemiological, animal, and cell culture studies are…”
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Controlled human exposures to wood smoke: a synthesis of the evidence
Published in Particle and fibre toxicology (02-10-2020)“…Abstract Background Exposure to particulate matter (PM) from wood combustion represents a global health risk, encompassing diverse exposure sources; indoor…”
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Health effects of residential wood smoke particles: the importance of combustion conditions and physicochemical particle properties
Published in Particle and fibre toxicology (06-11-2009)“…Residential wood combustion is now recognized as a major particle source in many developed countries, and the number of studies investigating the negative…”
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Differential effects of the particle core and organic extract of diesel exhaust particles
Published in Toxicology letters (05-02-2012)“…► Native DEP and methanol DEP-extract induced marked expression of COX-2, IL-6 and IL-8, as well as cytotoxicity. ► Residual DEPs did not induce the…”
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5
Transmaternal bisphenol A exposure accelerates diabetes type 1 development in NOD mice
Published in Toxicological sciences (01-02-2014)“…Diabetes mellitus type 1 is an autoimmune disease with a genetic predisposition that is triggered by environmental factors during early life. Epidemiological…”
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Peroxisome proliferator-activated receptor gamma gene variants modify human airway and systemic responses to indoor dibutyl phthalate exposure
Published in Respiratory research (16-09-2022)“…Single nucleotide polymorphisms (SNPs) of peroxisome proliferator-activated receptor gamma (PPAR-γ; gene: PPARG) and oxidative stress genes are associated with…”
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7
Concentrations of selected chemicals in indoor air from Norwegian homes and schools
Published in The Science of the total environment (15-07-2019)“…Both building materials and consumer products have been identified as possible sources for potentially hazardous substances like phthalates, polychlorinated…”
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Wood smoke particles from different combustion phases induce similar pro-inflammatory effects in a co-culture of monocyte and pneumocyte cell lines
Published in Particle and fibre toxicology (23-11-2012)“…Exposure to particulate matter (PM) has been linked to several adverse cardiopulmonary effects, probably via biological mechanisms involving inflammation. The…”
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The dental monomer 2-hydroxyethyl methacrylate (HEMA) causes transcriptionally regulated adaptation partially initiated by electrophilic stress
Published in Dental materials (01-01-2019)“…Cellular responses including cell death are induced by in vitro exposure to the un-polymerized dental monomer 2-hydroxyethyl methacrylate (HEMA). Activation of…”
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Early life exposure to bisphenol A investigated in mouse models of airway allergy, food allergy and oral tolerance
Published in Food and chemical toxicology (01-09-2015)“…The impact of early life exposure to bisphenol A (BPA) through drinking water was investigated in mouse models of respiratory allergy, food allergy and oral…”
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Bisphenol A Is More Potent than Phthalate Metabolites in Reducing Pancreatic β-Cell Function
Published in BioMed research international (01-01-2017)“…Bisphenol A (BPA) and phthalates are common environmental contaminants that have been proposed to influence incidence and development of types 1 and 2…”
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Mono-2-ethylhexylphthalate (MEHP) induces TNF-α release and macrophage differentiation through different signalling pathways in RAW264.7 cells
Published in Toxicology letters (25-02-2012)“…► MEHP caused differentiation and pro-inflammatory cytokine release in RAW cells. ► PPARs were involved in the differentiation but not in cytokine release. ►…”
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13
Burden of disease due to transportation noise in the Nordic countries
Published in Environmental research (15-08-2023)“…Environmental noise is of increasing concern for public health. Quantification of associated health impacts is important for regulation and preventive…”
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Dental monomers inhibit LPS-induced cytokine release from the macrophage cell line RAW264.7
Published in Toxicology letters (04-02-2013)“…► Low HEMA and TEGDMA levels reduced LPS-induced release of pro-inflammatory cytokines. ► Co-exposure to monomers caused additive effects on cytokine release…”
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Dibutyl phthalate exposure alters T‐cell subsets in blood from allergen‐sensitized volunteers
Published in Indoor air (01-04-2022)“…Phthalates are ubiquitous environmental contaminants associated with allergic disease in epidemiological and animal studies. This investigation aims to support…”
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Decreased macrophage phagocytic function due to xenobiotic exposures in vitro, difference in sensitivity between various macrophage models
Published in Food and chemical toxicology (01-02-2018)“…Both autoimmune disease prevalence and exposure to immunotoxic chemicals have increased the last decades. As a first screening of immunotoxic chemicals…”
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Long-term bisphenol A exposure accelerates insulitis development in diabetes-prone NOD mice
Published in Immunopharmacology and immunotoxicology (01-06-2013)“…Abstract Exposure to the endocrine disruptor (ED) bisphenol A (BPA) used in polycarbonate plastic and epoxy resins appears ubiquitous since BPA can be found in…”
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Di-n-butyl phthalate modifies PMA-induced macrophage differentiation of THP-1 monocytes via PPARγ
Published in Toxicology in vitro (01-02-2019)“…The present study examined the effects of di-n-butyl phthalate (DBP) on phorbol myristate acetate (PMA)-induced macrophage differentiation of THP-1 monocytes,…”
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Cytokine responses induced by diesel exhaust particles are suppressed by PAR-2 silencing and antioxidant treatment, and driven by polar and non-polar soluble constituents
Published in Toxicology letters (14-10-2015)“…•Antioxidants suppressed DEP-induced IL-6 and CXCL8 responses in BEAS-2B cells.•CXCL8 appeared more dependent on oxidant-mediated mechanisms than IL-6.•PAR-2…”
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The occurrence of polycyclic aromatic hydrocarbons and their derivatives and the proinflammatory potential of fractionated extracts of diesel exhaust and wood smoke particles
Published in Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering (21-03-2014)“…Exposure to combustion emissions, including diesel engine exhaust and wood smoke particles (DEPs and WSPs), has been associated with inflammatory responses. To…”
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