Search Results - "Koc, Michal"

Lymphedema alters lipolytic, lipogenic, immune and angiogenic properties of adipose tissue: a hypothesis-generating study in breast cancer survivors by Koc, Michal, Wald, Martin, Varaliová, Zuzana, Ondrůjová, Barbora, Čížková, Terezie, Brychta, Milan, Kračmerová, Jana, Beranová, Lenka, Pala, Jan, Šrámková, Veronika, Šiklová, Michaela, Gojda, Jan, Rossmeislová, Lenka

“…Later stages of secondary lymphedema are associated with the massive deposition of adipose tissue (AT). The factors driving lymphedema-associated AT (LAT)…”
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BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study by Makrodouli, Eleni, Oikonomou, Eftychia, Koc, Michal, Andera, Ladislav, Sasazuki, Takehiko, Shirasawa, Senji, Pintzas, Alexander

“…Colorectal cancer is a common disease that involves genetic alterations, such as inactivation of tumour suppressor genes and activation of oncogenes. Among…”
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Inhibition of Lipolysis Ameliorates Diabetic Phenotype in a Mouse Model of Obstructive Sleep Apnea by Weiszenstein, Martin, Shimoda, Larissa A, Koc, Michal, Seda, Ondrej, Polak, Jan

“…Obstructive sleep apnea (OSA) is associated with insulin resistance, glucose intolerance, and type 2 diabetes. Causal mechanisms mediating this association are…”
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Exercise Training Combined with Calanus Oil Supplementation Improves the Central Cardiodynamic Function in Older Women by Štěpán, Marek, Daďová, Klára, Matouš, Miloš, Krauzová, Eva, Sontáková, Lenka, Koc, Michal, Larsen, Terje, Kuda, Ondrej, Štich, Vladimír, Rossmeislová, Lenka, Šiklová, Michaela

“…The aim of this study was to investigate the possible beneficial effects of exercise training (ET) with omega-3/Calanus oil supplementation on…”
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Selective BRAFV600E inhibitor PLX4720, requires TRAIL assistance to overcome oncogenic PIK3CA resistance by Oikonomou, Eftychia, Koc, Michal, Sourkova, Vladimira, Andera, Ladislav, Pintzas, Alexander

“…Documented sensitivity of melanoma cells to PLX4720, a selective BRAFV600E inhibitor, is based on the presence of mutant BRAF(V600E) alone, while wt-BRAF or…”
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Signs of Deregulated Gene Expression Are Present in Both CD14 + and CD14 - PBMC From Non-Obese Men With Family History of T2DM by Koc, Michal, Šiklová, Michaela, Šrámková, Veronika, Štěpán, Marek, Krauzová, Eva, Štich, Vladimír, Rossmeislová, Lenka

“…Development of type 2 diabetes (T2DM) is associated with disturbances in immune and metabolic status that may be reflected by an altered gene expression…”
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Obesity alters adipose tissue response to fasting and refeeding in women: A study on lipolytic and endocrine dynamics and acute insulin resistance by Rossmeislová, Lenka, Krauzová, Eva, Koc, Michal, Wilhelm, Marek, Šebo, Viktor, Varaliová, Zuzana, Šrámková, Veronika, Schouten, Moniek, Šedivý, Petr, Tůma, Petr, Kovář, Jan, Langin, Dominique, Gojda, Jan, Šiklová, Michaela

“…Fasting induces significant shifts in substrate utilization with signs of acute insulin resistance (IR), while obesity is associated with chronic IR…”
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Ursodeoxycholic acid but not tauroursodeoxycholic acid inhibits proliferation and differentiation of human subcutaneous adipocytes by Mališová, Lucia, Kováčová, Zuzana, Koc, Michal, Kračmerová, Jana, Stich, Vladimír, Rossmeislová, Lenka

“…Stress of endoplasmic reticulum (ERS) is one of the molecular triggers of adipocyte dysfunction and chronic low inflammation accompanying obesity. ERS can be…”
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Circulating Monocyte and Lymphocyte Populations in Healthy First-Degree Relatives of Type 2 Diabetic Patients at Fasting and during Short-Term Hyperinsulinemia by Rossmeislová, Lenka, Koc, Michal, Štěpán, Marek, Kračmerová, Jana, Svobodová, Barbora, Krauzová, Eva, Šiklová, Michaela, Štich, Vladimír

“…Aim. The development of type 2 diabetes (T2DM) is associated with disturbances of immune status that may be reflected by alterations of the profile of…”
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The Effect of Hypoxia and Metformin on Fatty Acid Uptake, Storage, and Oxidation in L6 Differentiated Myotubes by Musutova, Martina, Elkalaf, Moustafa, Klubickova, Natalie, Koc, Michal, Povysil, Stanislav, Rambousek, Jan, Volckaert, Beatriz, Duska, Frantisek, Trinh, Minh Duc, Kalous, Martin, Trnka, Jan, Balusikova, Kamila, Kovar, Jan, Polak, Jan

“…Metabolic impairments associated with obstructive sleep apnea syndrome (OSA) are linked to tissue hypoxia, however, the explanatory molecular and endocrine…”
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Development of Radiofrequency Ablation Generator and Balloon-Based Catheter for Microendoluminal Thin-Layer Ablation Therapy Using the Rat Duodenum as a Model of Low-Impedance Tissue by Nociarova, Jana, Novak, Marek, Polak, Jan, Hrudka, Jan, Porubsky, Stefan, Koc, Michal, Rosina, Jozef, Grebenyuk, Aleksandr N., Sery, Radek, Gurlich, Robert, Hajer, Jan

“…Radiofrequency ablation (RFA) is a routinely used, safe, and effective method for the tissue destruction. Often, in case of its application in malignant…”
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Cell Death Induced by Taxanes in Breast Cancer Cells: Cytochrome c is Released in Resistant but not in Sensitive Cells by EHRLICHOVA, Marie, KOC, Michal, TRUKSA, Jaroslav, NALDOVA, Zuzana, VACLAVIKOVA, Radka, KOVARR, Jan

“…Background: The aim of the study was to contribute to our understanding of the mechanisms responsible for the resistance of breast cancer cells to taxanes…”
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Sensitive monitoring of 3-hydroxybutyrate as an indicator of human fasting by capillary electrophoresis in a PAMAMPS coated capillary by Tůma, Petr, Sommerová, Blanka, Koval, Dušan, Šiklová, Michaela, Koc, Michal

“…Sensitive electrophoretic determination of 3-hydroxybutyrate (3HB) as an indicator of human ketogenesis is performed in fused silica capillary covalently…”
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Plasma levels of creatine, 2-aminobutyric acid, acetyl-carnitine and amino acids during fasting measured by counter-current electrophoresis in PAMAPTAC capillary by Tůma, Petr, Sommerová, Blanka, Koval, Dušan, Šiklová, Michaela, Koc, Michal

“…[Display omitted] •Simultaneous determination of creatine, 2-aminobutyric acid, acetyl-carnitine, amino acids.•Counter-current separation of metabolites in…”
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Intermittent Hypoxia Stimulates Lipolysis, But Inhibits Differentiation and De Novo Lipogenesis in 3T3-L1 Cells by Musutova, Martina, Weiszenstein, Martin, Koc, Michal, Polak, Jan

“…Exposure to intermittent hypoxia (IH) may play a role in the development of metabolic impairments in the context of obstructive sleep apnea syndrome, probably…”
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Liver fat response to two days fasting and two days isocaloric high-carbohydrate refeeding in lean and obese women by Šedivý, Petr, Dusilová, Tereza, Šetinová, Bára, Pajuelo, Dita, Hájek, Milan, Rossmeislová, Lenka, Šiklová, Michaela, Šrámková, Veronika, Krauzová, Eva, Gojda, Jan, Koc, Michal, Dezortová, Monika, Kovář, Jan

“…Prolonged fasting, which leads to the mobilization of fat from adipose tissue, can result in the development of hepatosteatosis. However, it is not yet known…”
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Serum OxLDL-B2GPI Complex reflects inflammation in visceral adipose tissue by Siklova, Michaela, Koc, Michal, Rossmeislova, Lenka, Kraml, Pavel

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Exercise Training Reduces Inflammation of Adipose Tissue in the Elderly: Cross-Sectional and Randomized Interventional Trial by Čížková, Terezie, Štěpán, Marek, Daďová, Klára, Ondrůjová, Barbora, Sontáková, Lenka, Krauzová, Eva, Matouš, Miloš, Koc, Michal, Gojda, Jan, Kračmerová, Jana, Štich, Vladimír, Rossmeislová, Lenka, Šiklová, Michaela

“…Abstract Context Metabolic disturbances and a pro-inflammatory state associated with aging and obesity may be mitigated by physical activity or nutrition…”
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The role of adipogenic capacity and dysfunctional subcutaneous adipose tissue in the inheritance of type 2 diabetes mellitus: cross‐sectional study by Šiklová, Michaela, Šrámková, Veronika, Koc, Michal, Krauzová, Eva, Čížková, Terezie, Ondrůjová, Barbora, Wilhelm, Marek, Varaliová, Zuzana, Kuda, Ondrej, Neubert, Jana, Lambert, Lukáš, Elkalaf, Moustafa, Gojda, Jan, Rossmeislová, Lenka

“…Objective This study tested the hypothesis that limited subcutaneous adipose tissue (SAT) expansion represents a primary predisposition to the development of…”
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Adipogenesis, lipogenesis and lipolysis is stimulated by mild but not severe hypoxia in 3T3-L1 cells by Weiszenstein, Martin, Musutova, Martina, Plihalova, Andrea, Westlake, Katerina, Elkalaf, Moustafa, Koc, Michal, Prochazka, Antonin, Pala, Jan, Gulati, Sumeet, Trnka, Jan, Polak, Jan

“…In-vitro investigation of the effects of hypoxia is limited by physical laws of gas diffusion and cellular O2 consumption, making prolonged exposures to stable…”
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