Search Results - "Kobitzsch, Benjamin"
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Loss-of-function but not dominant-negative intragenic IKZF1 deletions are associated with an adverse prognosis in adult BCR-ABL -negative acute lymphoblastic leukemia
Published in Haematologica (Roma) (01-10-2017)“…Genetic alterations of the transcription factor IKZF1 ("IKAROS") are detected in around 15-30% of cases of -negative B-cell precursor acute lymphoblastic…”
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Plasma EBV DNA as a prognostic factor in EBV associated gastric cancer: a multicenter, prospective study (EBV PRESAGE study)
Published in Frontiers in oncology (24-10-2023)“…PurposeThe Cancer Genome Atlas Research Network identified Epstein-Barr-Virus (EBV)-positive gastric cancer as a distinct molecular subtype. The prevalence is…”
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Exceptional Response of BRAF V600E -Mutated Acinar Cell CUP to BRAF/MEK Inhibition
Published in JCO precision oncology (01-05-2024)“…Complete remission of BRAF V600E-driven ACC CUP by BRAF/MEK inhibition underscores importance of precision oncology…”
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Non-Functional ("haploinsufficient"), but Not Dominant Negative Clonal IKZF1 Deletions Confer an Adverse Prognosis in Adult BCR-ABL-Negative Acute Lymphoblastic Leukemia
Published in Blood (03-12-2015)“…Background: IKAROS (IKZF1) is a key transcription factor for B-cell development. The IKZF1 protein exerts its functions as a dimer (homodimer or heterodimer…”
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Kolonkarzinom
Published in Coloproctology (01-04-2024)“…Zusammenfassung Das Kolonkarzinom ist ein häufiges Karzinom mit steigender Inzidenz im Alter. Mit Vorsorgekoloskopien lässt es sich frühzeitig diagnostizieren…”
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