Search Results - "Kobayashi, Ryoki"
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Oral bacteria affect the gut microbiome and intestinal immunity
Published in Pathogens and disease (01-04-2020)“…ABSTRACT Recently, it has been suggested that the oral administration of Porphyromonas gingivalis, a keystone pathogen for periodontal disease, induces…”
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2
Impaired salivary SIgA antibodies elicit oral dysbiosis and subsequent induction of alveolar bone loss
Published in Inflammation research (01-01-2021)“…Objective Secreted IgA (SIgA) plays a central role in preventing bacterial and viral infections on mucosal surfaces by neutralizing toxins and viruses and…”
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3
Regulation of the NLRP3 inflammasome in Porphyromonas gingivalis-accelerated periodontal disease
Published in Inflammation research (01-01-2017)“…Objective Porphyromonas gingivalis is involved in the pathogenesis of chronic inflammatory periodontal disease. Recent studies have suggested that the NLRP3…”
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4
Female reproductive tract-organ axes
Published in Frontiers in immunology (31-01-2023)“…The female reproductive tract (FRT) and remote/versatile organs in the body share bidirectional communication. In this review, we discuss the framework of the…”
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5
Lactic acid bacteria prevent both periodontitis and atherosclerosis exacerbated by periodontitis in spontaneously hyperlipidemic mice
Published in Journal of periodontal research (01-08-2021)“…Background and Objective Recent studies have shown a link between periodontal disease and cardiovascular disease. We have previously reported that oral…”
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6
Enhancing dementia risk screening with GAN-synthesized periodontal examination and general blood test data
Published in Frontiers in neurology (14-08-2024)“…This study aimed to investigate the effectiveness of data augmentation to improve dementia risk prediction using machine learning models. Recent studies have…”
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7
Activation of the NLRP3 inflammasome in Porphyromonas gingivalis-accelerated atherosclerosis
Published in Pathogens and disease (01-06-2015)“…Porphyromonas gingivalis has been shown to accelerate atherosclerotic lesion development in hyperlipidemic animals. Atherosclerosis is a disease characterized…”
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Lactobacillus helveticus SBT2171 upregulates the expression of β‐defensin and ameliorates periodontal disease caused by Porphyromonas gingivalis
Published in Microbiology and immunology (01-08-2019)“…Antimicrobial peptides play important roles in the innate immune system of various organisms, and they may also be considered to prevent the organisms from…”
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Association between Dietary Habit and Clinical Parameters in Patients with Chronic Periodontitis Undergoing Supportive Periodontal Therapy
Published in Nutrients (24-11-2022)“…The recurrence risk evaluation has been emphasized in periodontal stabilization during supportive periodontal therapy (SPT). However, nutritional factors,…”
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10
Lymphocyte antigen 6 complex locus G6D downregulation is a novel parameter for functional impairment of neutrophils in aged mice
Published in Frontiers in immunology (27-10-2022)“…Immunological aging is a critical event that causes serious functional impairment in the innate immune system. However, the identification markers and…”
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11
Porphyromonas gingivalis infection enhances Th17 responses for development of atherosclerosis
Published in Archives of oral biology (01-11-2014)“…Highlights • Porphyromonas gingivalis is associated with the acceleration of atherosclerosis. • Atherosclerosis involves T cell-related chronic inflammatory…”
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12
Identification of Nutritional Factors to Evaluate Periodontal Clinical Parameters in Patients with Systemic Diseases
Published in Nutrients (11-01-2023)“…Nutritional factors reflect the periodontal parameters accompanying periodontal status. In this study, the associations between nutritional factors, blood…”
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13
Secretory-IgA antibodies play an important role in the immunity to Streptococcus pneumoniae
Published in The Journal of immunology (1950) (01-08-2010)“…This study was designed to investigate whether secretory-IgA (S-IgA) Abs induced by a pneumococcal surface protein A (PspA)-based nasal vaccine are necessary…”
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Evaluation of suitable antigens and adjuvant concentration for sublingual immunization to prevent periodontal disease
Published in Oral science international (01-08-2019)“…The oral cavity is dominated by both mucosal and systemic immune systems, due to the presence of immunoglobulin (Ig)A antibodies (Abs) in saliva and IgG Abs in…”
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Localization and expression pattern of amelotin, odontogenic ameloblast-associated protein and follicular dendritic cell-secreted protein in the junctional epithelium of inflamed gingiva
Published in Odontology (01-07-2017)“…[Abstract] The purpose of this study is to elucidate the localization of amelotin (AMTN), odontogenic ameloblast-associated protein (ODAM) and follicular…”
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A combination of Flt3 ligand cDNA and CpG oligodeoxynucleotide as nasal adjuvant elicits protective secretory-IgA immunity to Streptococcus pneumoniae in aged mice
Published in The Journal of immunology (1950) (15-02-2011)“…Our previous study showed that a combination of a plasmid-expressing Flt3 ligand (pFL) and CpG oligodeoxynucleotides (CpG ODN) as a combined nasal adjuvant…”
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Oral immunization with Porphyromonas gingivalis outer membrane protein and CpG oligodeoxynucleotides attenuates P. gingivalis-accelerated atherosclerosis and inflammation
Published in Journal of oral biosciences (01-11-2017)“…It has previously been shown that oral immunization with the 40-kDa outer membrane protein of Porphyromonas gingivalis (40k-OMP) and CpG oligodeoxynucleotides…”
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18
Functional transforming growth factor-β receptor type II expression by CD4+ T cells in Peyer's patches is essential for oral tolerance induction
Published in PloS one (07-11-2011)“…Our previous studies have shown that Peyer's patches (PPs) play a key role in the induction of oral tolerance. Therefore, we hypothesized that PPs are an…”
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Pseudopropionibacterium rubrum sp. nov., a novel red‐pigmented species isolated from human gingival sulcus
Published in Microbiology and immunology (01-06-2018)“…ABSTRACT In this study, sStrain SK‐1T, a novel gram‐positive, pleomorphic, rod‐shaped, non‐spore forming, non‐motile organism, designated SK‐1T, was isolated…”
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Nasal immunization with the 40-kDa outer membrane protein of Porphyromonas gingivalis plus cholera toxin induces protective immunity in aged mice
Published in Journal of Oral Science (2013)“…Previous studies have demonstrated that nasal administration of the outer membrane protein of Porphyromonas gingivalis (40k-OMP) with cholera toxin (CT) as an…”
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