Search Results - "Kobayashi, Kyousuke"

Cellular receptors for enterovirus A71 by Kobayashi, Kyousuke, Koike, Satoshi

“…Enterovirus 71 (EV-A71) is one of the major causative agents of hand, foot, and mouth disease. EV-A71 infection is sometimes associated with severe…”
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Adaptation and Virulence of Enterovirus-A71 by Kobayashi, Kyousuke, Koike, Satoshi

“…Outbreaks of hand, foot, and mouth disease caused by enterovirus-A71 (EV-A71) can result in many deaths, due to central nervous system complications. Outbreaks…”
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Amino Acid Variation at VP1-145 of Enterovirus 71 Determines Attachment Receptor Usage and Neurovirulence in Human Scavenger Receptor B2 Transgenic Mice by Kobayashi, Kyousuke, Sudaka, Yui, Takashino, Ayako, Imura, Ayumi, Fujii, Ken, Koike, Satoshi

“…Infection by enterovirus 71 (EV71) is affected by cell surface receptors, including the human scavenger receptor B2 (hSCARB2), which are required for viral…”
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Heparan sulfate attachment receptor is a major selection factor for attenuated enterovirus 71 mutants during cell culture adaptation by Kobayashi, Kyousuke, Mizuta, Katsumi, Koike, Satoshi

“…Enterovirus 71 (EV71) is a causative agent of hand, foot, and mouth disease (HFMD). However, this infection is sometimes associated with severe neurological…”
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Mouse Scarb2 Modulates EV-A71 Pathogenicity in Neonatal Mice by Miwatashi, Wakako, Ishida, Minori, Takashino, Ayako, Kobayashi, Kyousuke, Yamaguchi, Midori, Shitara, Hiroshi, Koike, Satoshi

“…Enterovirus A71 (EV-A71) is a human pathogen that causes hand, foot, and mouth disease, which can progress to severe neurological disease. EV-A71 infects…”
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Anticancer effects of a non-narcotic opium alkaloid medicine, papaverine, in human glioblastoma cells by Inada, Mana, Shindo, Mika, Kobayashi, Kyousuke, Sato, Akira, Yamamoto, Yohei, Akasaki, Yasuharu, Ichimura, Koichi, Tanuma, Sei-Ichi

“…The interaction between high-mobility group box 1 protein (HMGB1) and receptor for advanced glycation end products (RAGE) is important for tumor cell growth…”
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VP1 Amino Acid Residue 145 of Enterovirus 71 Is a Key Residue for Its Receptor Attachment and Resistance to Neutralizing Antibody during Cynomolgus Monkey Infection by Fujii, Ken, Sudaka, Yui, Takashino, Ayako, Kobayashi, Kyousuke, Kataoka, Chikako, Suzuki, Tadaki, Iwata-Yoshikawa, Naoko, Kotani, Osamu, Ami, Yasushi, Shimizu, Hiroyuki, Nagata, Noriyo, Mizuta, Katsumi, Matsuzaki, Yoko, Koike, Satoshi

“…Enterovirus 71 (EV71) is a causative agent of hand, foot, and mouth disease and sometimes causes severe or fatal neurological complications. The amino acid at…”
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Virulence of Enterovirus A71 Fluctuates Depending on the Phylogenetic Clade Formed in the Epidemic Year and Epidemic Region by Kobayashi, Kyousuke, Nishimura, Hidekazu, Mizuta, Katsumi, Nishizawa, Tomoha, Chu, Son T, Ichimura, Hiroshi, Koike, Satoshi

“…Although epidemics of hand, foot, and mouth disease (HFMD) caused by enterovirus A71 (EV-A71) have occurred worldwide, the Asia-Pacific region has seen large…”
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The role of the SWI/SNF chromatin remodeling complex in maintaining the stemness of glioma initiating cells by Hiramatsu, Hiroaki, Kobayashi, Kazuyoshi, Kobayashi, Kyousuke, Haraguchi, Takeshi, Ino, Yasushi, Todo, Tomoki, Iba, Hideo

“…Glioma initiating cells (GICs) are thought to contribute to therapeutic resistance and tumor recurrence in glioblastoma, a lethal primary brain tumor in…”
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Development of an Enterovirus 71 Vaccine Efficacy Test Using Human Scavenger Receptor B2 Transgenic Mice by Imura, Ayumi, Sudaka, Yui, Takashino, Ayako, Tamura, Kanami, Kobayashi, Kyousuke, Nagata, Noriyo, Nishimura, Hidekazu, Mizuta, Katsumi, Koike, Satoshi

“…Enterovirus 71 (EV71) is a causative agent of hand-foot-mouth disease, and it sometimes causes severe neurological disease. Development of effective vaccines…”
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Evaluating the use of heparin for synchronization of in vitro culture of Plasmodium falciparum by Kobayashi, Kyousuke, Kato, Kentaro

“…Abstract The malaria parasite Plasmodium falciparum infects human erythrocytes and reproduces asexually through an intraerythrocytic developmental cycle. In…”
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TAK − 021, an inactivated Enterovirus 71 vaccine candidate, provides cross-protection against heterologous sub-genogroups in human scavenger receptor B2 transgenic mice by Tamura, Kanami, Kohnoe, Mai, Takashino, Ayako, Kobayashi, Kyousuke, Koike, Satoshi, Karwal, Lovkesh, Fukuda, Shigeru, Vang, Fue, Das, Subash C., Dean, Hansi J.

“…•Hand, foot and mouth disease (HFMD) is frequently caused by enterovirus 71 (EV71)•HFMD is emerging as a major public health concern in the Asia-Pacific…”
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Newly emerged enterovirus-A71 C4 sublineage may be more virulent than B5 in the 2015–2016 hand-foot-and-mouth disease outbreak in northern Vietnam by Chu, Son T., Kobayashi, Kyousuke, Bi, Xiuqiong, Ishizaki, Azumi, Tran, Tu T., Phung, Thuy T. B., Pham, Chung T. T., Nguyen, Lam V., Ta, Tuan A., Khu, Dung T. K., Agoh, Masanobu, Pham, An N., Koike, Satoshi, Ichimura, Hiroshi

“…Enterovirus-A71 (EV-A71) is a common cause of hand-foot-and-mouth disease (HFMD) and, rarely, causes severe neurological disease. This study aimed to elucidate…”
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Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition by Haraguchi, Takeshi, Kondo, Masayuki, Uchikawa, Ryo, Kobayashi, Kazuyoshi, Hiramatsu, Hiroaki, Kobayashi, Kyousuke, Chit, Ung Weng, Shimizu, Takanobu, Iba, Hideo

“…Whereas miR-200 family is known to be involved in the epithelial-to-mesenchymal transition (EMT), a crucial biological process observed in normal and…”
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MiR-199a Inhibits Secondary Envelopment of Herpes Simplex Virus-1 Through the Downregulation of Cdc42-specific GTPase Activating Protein Localized in Golgi Apparatus by Kobayashi, Kyousuke, Suemasa, Fumiko, Sagara, Hiroshi, Nakamura, Shinya, Ino, Yasushi, Kobayashi, Kazuyoshi, Hiramatsu, Hiroaki, Haraguchi, Takeshi, Kurokawa, Kazuo, Todo, Tomoki, Nakano, Akihiko, Iba, Hideo

“…Because several studies have shown that exogenous miR-199a has antiviral effects against various viruses, including herpesviruses, we examined how miR-199a…”
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Plasmodium falciparum BAEBL Binds to Heparan Sulfate Proteoglycans on the Human Erythrocyte Surface by Kobayashi, Kyousuke, Kato, Kentaro, Sugi, Tatsuki, Takemae, Hitoshi, Pandey, Kishor, Gong, Haiyan, Tohya, Yukinobu, Akashi, Hiroomi

“…Erythrocyte invasion is critical to the pathogenesis and survival of the malarial parasite, Plasmodium falciparum. This process is partly mediated by proteins…”
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Toxoplasma gondii RON4 binds to heparan sulfate on the host cell surface by Takemae, Hitoshi, Kobayashi, Kyousuke, Sugi, Tatsuki, Han, Yongmei, Gong, Haiyan, Ishiwa, Akiko, Recuenco, Frances C., Murakoshi, Fumi, Takano, Ryo, Murata, Yuho, Nagamune, Kisaburo, Horimoto, Taisuke, Akashi, Hiroomi, Kato, Kentaro

“…Toxoplasma gondii rhoptry neck protein 4 (TgRON4) is a component of the moving junction, a key structure for host cell invasion. We previously showed that host…”
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A novel PAN/apple domain-containing protein from Toxoplasma gondii: characterization and receptor identification by Gong, Haiyan, Kobayashi, Kyousuke, Sugi, Tatsuki, Takemae, Hitoshi, Kurokawa, Hitomi, Horimoto, Taisuke, Akashi, Hiroomi, Kato, Kentaro

“…Toxoplasma gondii is an intracellular parasite that invades nucleated cells, causing toxoplasmosis in humans and animals worldwide. The extremely wide range of…”
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Identification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growth by Kurokawa, Hitomi, Kato, Kentaro, Iwanaga, Tatsuya, Sugi, Tatsuki, Sudo, Atsushi, Kobayashi, Kyousuke, Gong, Haiyan, Takemae, Hitoshi, Recuenco, Frances C, Horimoto, Taisuke, Akashi, Hiroomi

“…cAMP-dependent protein kinase (PKA) has been implicated in the asexual stage of the Toxoplasma gondii life cycle through assaying the effect of a PKA-specific…”
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Pull-down method to access the cell surface receptor for Toxoplasma gondii by Gong, Haiyan, Kobayashi, Kyousuke, Sugi, Tatsuki, Takemae, Hitoshi, Horimoto, Taisuke, Xuan, Xuenan, Akashi, Hiroomi, Kato, Kentaro

“…Abstract Protein X, which is expressed on the surface of Toxoplasma and is thought to interact with host molecules, was expressed as a GST recombinant protein,…”
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