Search Results - "Koban, Florian"

Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff by Ranftler, Carmen, Nagl, Dietmar, Sparer, Andreas, Röhrich, Andreas, Freissmuth, Michael, El-Kasaby, Ali, Nasrollahi Shirazi, Shahrooz, Koban, Florian, Tschegg, Cornelius, Nizet, Stephane

“…Clostridioides difficile (C . difficile) infection is a major public health problem worldwide. The current treatment of C . difficile -associated diarrhea…”
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STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior by Kong, Eryan, Sucic, Sonja, Monje, Francisco J., Reisinger, Sonali N., Savalli, Giorgia, Diao, Weifei, Khan, Deeba, Ronovsky, Marianne, Cabatic, Maureen, Koban, Florian, Freissmuth, Michael, Pollak, Daniela D.

“…Experimental evidence suggests a role for the immune system in the pathophysiology of depression. A specific involvement of the proinflammatory cytokine…”
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The urokinase receptor (CD87) represents a central mediator of growth factor-induced endothelial cell migration by Poettler, Marina, Unseld, Matthias, Mihaly-Bison, Judit, Uhrin, Pavel, Koban, Florian, Binder, Bernd R, Zielinski, Christoph C, Prager, Gerald W

“…Angiogenesis, the sprouting of blood vessels form pre-existing vasculature after injury or in neoplastic diseases, is initiated by growth factor-induced…”
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The cell cycle protein MAD2 facilitates endocytosis of the serotonin transporter in the neuronal soma by Koban, Florian, Freissmuth, Michael

“…Monoamine transporters retrieve serotonin (SERT), dopamine (DAT), and norepinephrine (NET) from the synaptic cleft. Transporter internalization contributes to…”
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Thermal Unfolding of the Human Serotonin Transporter: Differential Effect by Stabilizing and Destabilizing Mutations and Cholesterol on Thermodynamic and Kinetic Stability by Ponleitner, Markus, Szöllősi, Daniel, El-Kasaby, Ali, Koban, Florian, Freissmuth, Michael, Stockner, Thomas

“…Folding-deficient mutants of solute carrier 6 (SLC6) family members have been linked to human diseases. The serotonin transporter [(SERT)/SLC6A4] is an…”
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Breaking the rules of SLC6 transporters: Export of the human creatine transporter‐1 from the endoplasmic reticulum is supported by its N‐terminus by Ün, Didem, Kovalchuk, Vasylyna, El‐Kasaby, Ali, Kasture, Ameya, Koban, Florian, Kudlacek, Oliver, Freissmuth, Michael, Sucic, Sonja

“…Mutations in the human creatine transporter 1 (CRT1/SLC6A8) cause the creatine transporter deficiency syndrome, which is characterized by intellectual…”
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Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome by El-Kasaby, Ali, Kasture, Ameya, Koban, Florian, Hotka, Matej, Asjad, Hafiz M.M., Kubista, Helmut, Freissmuth, Michael, Sucic, Sonja

“…Diseases arising from misfolding of SLC6 transporters have been reported over recent years, e.g. folding-deficient mutants of the dopamine transporter and of…”
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A Cytosolic Relay of Heat Shock Proteins HSP70-1A and HSP90β Monitors the Folding Trajectory of the Serotonin Transporter by El-Kasaby, Ali, Koban, Florian, Sitte, Harald H., Freissmuth, Michael, Sucic, Sonja

“…Mutations in the C terminus of the serotonin transporter (SERT) disrupt folding and export from the endoplasmic reticulum. Here we examined the hypothesis that…”
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A Salt Bridge Linking the First Intracellular Loop with the C Terminus Facilitates the Folding of the Serotonin Transporter by Koban, Florian, El-Kasaby, Ali, Häusler, Cornelia, Stockner, Thomas, Simbrunner, Benedikt M., Sitte, Harald H., Freissmuth, Michael, Sucic, Sonja

“…The folding trajectory of solute carrier 6 (SLC6) family members is of interest because point mutations result in misfolding and thus cause clinically relevant…”
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Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C by Sucic, Sonja, Koban, Florian, El-Kasaby, Ali, Kudlacek, Oliver, Stockner, Thomas, Sitte, Harald H, Freissmuth, Michael

“…The serotonin transporter (SERT) maintains serotonergic neurotransmission via rapid reuptake of serotonin from the synaptic cleft. SERT relies exclusively on…”
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Treprostinil reduces endothelial damage in murine sinusoidal obstruction syndrome by Themanns, Madeleine, Koban, Florian, Bergmayr, Christian, Chrzan, Alicja, Strohmaier, Wolfgang, Haybaeck, Johannes, Freissmuth, Michael, Zebedin-Brandl, Eva

“…Sinusoidal obstruction syndrome (SOS) is a major complication after hematopoietic stem cell transplantation and belongs to a group of diseases increasingly…”
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An Ionic Lock Between Intracellular Loop 1 and a C‐terminal Amphipathic Helix Stabilizes the Serotonin Transporter Along its Folding Trajectory by Sucic, Sonja, El‐Kasaby, Ali, Koban, Florian, Freissmuth, Michael

“…Abstract only The serotonin transporter (SERT) terminates neurotransmission via rapid reuptake of serotonin from the synaptic cleft. ER export of solute…”
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Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum by Montgomery, Therese R, Steinkellner, Thomas, Sucic, Sonja, Koban, Florian, Schüchner, Stefan, Ogris, Egon, Sitte, Harald H, Freissmuth, Michael

“…Export of the serotonin transporter (SERT) from the endoplasmic reticulum (ER) is mediated by the SEC24C isoform of the coatomer protein-II complex. SERT must…”
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Switching the Clientele by Sucic, Sonja, Koban, Florian, El-Kasaby, Ali, Kudlacek, Oliver, Stockner, Thomas, Sitte, Harald H., Freissmuth, Michael

“…The serotonin transporter (SERT) maintains serotonergic neurotransmission via rapid reuptake of serotonin from the synaptic cleft. SERT relies exclusively on…”
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Tracking Single Serotonin Transporter Molecules at the Endoplasmic Reticulum and Plasma Membrane by Anderluh, Andreas, Klotzsch, Enrico, Ries, Jonas, Reismann, Alexander W.A.F., Weber, Stefan, Fölser, Martin, Koban, Florian, Freissmuth, Michael, Sitte, Harald H., Schütz, Gerhard J.

“…Transmembrane proteins are synthesized and folded in the endoplasmic reticulum (ER), an interconnected network of flattened sacs or tubes. Up to now, this…”
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Correction: Corrigendum: STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behaviour by Kong, Eryan, Sucic, Sonja, Monje, Francisco J., Reisinger, Sonali N., Savalli, Giorgia, Diao, Weifei, Khan, Deeba, Ronovsky, Marianne, Cabatic, Maureen, Koban, Florian, Freissmuth, Michael, Pollak, Daniela D.

“…Experimental evidence suggests a role for the immune system in the pathophysiology of depression. A specific involvement of the proinflammatory cytokine…”
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Characterising the interaction between the COPII component SEC24C and the human serotonin transporter by Koban, Florian, Sucic, Sonja

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How does the carboxyl terminus assist folding and ER export of the serotonin transporter? by El-Kasaby, Ali, Koban, Florian, Freissmuth, Michael, Sucic, Sonja

“…Doc number: A55…”
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Corrigendum: STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behaviour by Kong, Eryan, Sucic, Sonja, Monje, Francisco J, Reisinger, Sonali N, Savalli, Giorgia, Diao, Weifei, Khan, Deeba, Ronovsky, Marianne, Cabatic, Maureen, Koban, Florian, Freissmuth, Michael, Pollak, Daniela D

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