Search Results - "Koba, Marcin"
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Amino acid profiling as a method of discovering biomarkers for diagnosis of neurodegenerative diseases
Published in Amino acids (01-03-2019)“…The trend of growing population of 60+ years old people is visible in most of the highly developed European countries. Recently researchers have shown an…”
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Application of Capillary Electrophoresis to the Analysis of Bioactive Compounds in Herbal Raw Materials
Published in Molecules (Basel, Switzerland) (08-04-2021)“…The article is a summary of scientific reports from the last 16 years (2005-2021) on the use of capillary electrophoresis to analyze polyphenolic compounds,…”
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3
Piperazine derivatives as dangerous abused compounds
Published in Acta pharmaceutica (Zagreb, Croatia) (01-12-2020)“…Piperazine derivatives are a group of compounds with a psychostimulant effect. They are an alternative to illegal drugs. They are being searched for…”
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4
Amino acid profiling as a method of discovering biomarkers for early diagnosis of cancer
Published in Amino acids (01-06-2016)“…Cancer is one of the main causes of mortality in the world and its early detection significantly increases chances of patients’ survival. High cancer mortality…”
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Novel Isosteviol-Based FXa Inhibitors: Molecular Modeling, In Silico Design and Docking Simulation
Published in Molecules (Basel, Switzerland) (24-06-2023)“…Direct oral anticoagulants are an important and relatively new class of synthetic anticoagulant drugs commonly used for the pharmacotherapy of thromboembolic…”
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6
Long-Period Gratings and Microcavity In-Line Mach Zehnder Interferometers as Highly Sensitive Optical Fiber Platforms for Bacteria Sensing
Published in Sensors (Basel, Switzerland) (05-07-2020)“…Selected optical fiber sensors offer extraordinary sensitivity to changes in external refractive (RI), which make them promising for label-free biosensing. In…”
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7
In silico design, docking simulation, and ANN-QSAR model for predicting the anticoagulant activity of thiourea isosteviol compounds as FXa inhibitors
Published in Chemical papers (01-11-2023)“…Novel oral anticoagulants are frequently used for the pharmacotherapy of thromboembolic disorders but still have drawbacks and side effects. While numerous…”
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8
Enhanced spectroelectrochemistry with lossy-mode resonance optical fiber sensor
Published in Scientific reports (19-09-2023)“…Spectroelectrochemical (SEC) measurements play a crucial role in analytical chemistry, utilizing transparent or semitransparent electrodes for optical analysis…”
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9
Comparative Analysis of Amino Acid Profiles in Patients with Glioblastoma and Meningioma Using Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC-ESI-MS/MS)
Published in Molecules (Basel, Switzerland) (22-11-2023)“…Brain tumors account for 1% of all cancers diagnosed de novo. Due to the specificity of the anatomical area in which they grow, they can cause significant…”
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10
Predicting Antitumor Activity of Anthrapyrazole Derivatives using Advanced Machine Learning Techniques
Published in Current computer-aided drug design (01-01-2024)“…Anthrapyrazoles are a new class of antitumor agents and successors to anthracyclines possessing a broad range of antitumor activity in various model tumors…”
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Safety Assessment of Foods and Drinks Consumed by People on a Gluten-Free Diet
Published in Molecules (Basel, Switzerland) (20-09-2022)“…Naturally gluten-free foods and processed foods that do not contain information about the potential presence of gluten in them pose a hypothetical threat to…”
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12
Electrochemically directed biofunctionalization of a lossy-mode resonance optical fiber sensor
Published in Optics express (25-05-2020)“…In this work, we present a direct electrochemical biofunctionalization of an indium-tin-oxide-coated lossy-mode resonance optical fiber sensor. The…”
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13
Recent Applications of Capillary Electrophoresis in the Determination of Active Compounds in Medicinal Plants and Pharmaceutical Formulations
Published in Molecules (Basel, Switzerland) (07-07-2021)“…The present review summarizes scientific reports from between 2010 and 2019 on the use of capillary electrophoresis to quantify active constituents (i.e.,…”
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14
Application of Multivariate Adaptive Regression Splines (MARSplines) for Predicting Antitumor Activity of Anthrapyrazole Derivatives
Published in International journal of molecular sciences (04-05-2022)“…An approach using multivariate adaptive regression splines (MARSplines) was applied for quantitative structure-activity relationship studies of the antitumor…”
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15
Double-layer optical fiber interferometer with bio-layer-modified reflector for label-free biosensing of inflammatory proteins
Published in Scientific reports (04-10-2024)“…This work discusses label-free biosensing application of a double-layer optical fiber interferometer where the second layer tailors the reflection conditions…”
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16
Low-volume label-free SARS-CoV-2 detection with the microcavity-based optical fiber sensor
Published in Scientific reports (27-01-2023)“…Accurate and fast detection of viruses is crucial for controlling outbreaks of many diseases; therefore, to date, numerous sensing systems for their detection…”
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17
Quantitative Structure-Activity Relationship Analysis of Isosteviol-Related Compounds as Activated Coagulation Factor X (FXa) Inhibitors
Published in Nutrients (26-08-2022)“…Stevioside, one of the natural sweeteners extracted from stevia leaves, and its derivatives are considered to have numerous beneficial pharmacological…”
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18
Combined Long-Period Fiber Grating and Microcavity In-Line Mach-Zehnder Interferometer for Refractive Index Measurements with Limited Cross-Sensitivity
Published in Sensors (Basel, Switzerland) (24-04-2020)“…This work discusses sensing properties of a long-period grating (LPG) and microcavity in-line Mach-Zehnder interferometer (µIMZI) when both are induced in the…”
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19
Application of artificial neural networks for the prediction of antitumor activity of a series of acridinone derivatives
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-05-2012)“…Artificial neural networks (ANNs) have been applied for the quantitative structure-activity relationships (QSAR) studies of antitumor activity of acridinone…”
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Selected Drug-Likeness Properties of 2-Arylidene-indan-1,3-dione Derivatives-Chemical Compounds with Potential Anti-Cancer Activity
Published in Molecules (Basel, Switzerland) (30-08-2021)“…2-Arylidene-indan-1,3-done derivatives have very different properties, thanks to which they find various applications in science, medicine, and industry…”
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