Search Results - "Koška, Juraj"
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Increased thyroid volume, prevalence of thyroid antibodies and impaired fasting glucose in young adults from organochlorine cocktail polluted area: Outcome of transgenerational transmission?
Published in Chemosphere (Oxford) (01-10-2008)“…In 137 females (F) and 94 males (M) aged 21–35 years from organochlorines (OCs) polluted area (POLL) increased thyroid volume (ThV), prevalence of antibodies…”
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Multiple adverse thyroid and metabolic health signs in the population from the area heavily polluted by organochlorine cocktail (PCB, DDE, HCB, dioxin)
Published in Thyroid research (31-03-2009)“…Several our previous studies showed associations of increasing blood level of persistent organochlorinated pollutants (POPs) with individual thyroid and…”
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Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans
Published in Diabetes (New York, N.Y.) (01-07-2015)“…GLP-1 receptor (GLP-1R) agonists may improve endothelial function (EF) via metabolic improvement and direct vascular action. The current study determined the…”
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Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: focus on incretins
Published in Cardiovascular diabetology (07-07-2011)“…Cardiovascular disease (CVD) risk in type 2 diabetes (T2DM) is only partially reduced by intensive glycemic control. Diabetic dyslipidemia is suggested to be…”
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Incretins and preservation of endothelial function
Published in Cardiovascular & hematological agents in medicinal chemistry (01-12-2012)“…The endothelium is critical for multiple processes occurring on both sides of the vascular wall including regulation of blood flow, maintenance of blood…”
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A Human Model of Dietary Saturated Fatty Acid Induced Insulin Resistance
Published in Metabolism, clinical and experimental (01-11-2016)“…Abstract Background Increased consumption of high-fat diets is associated with the development of insulin resistance and type 2 diabetes. Current models to…”
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Plasma proteoforms of apolipoproteins C-I and C-II are associated with plasma lipids in the Multi-Ethnic Study of Atherosclerosis
Published in Journal of lipid research (01-09-2022)“…Apolipoproteins (apo) C-I and C-II are key regulators of triglyceride and HDL metabolism. Both exist as full-size native and truncated (apoC-I'; apoC-II')…”
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Association of low fasting C-peptide levels with cardiovascular risk, visit-to-visit glucose variation and severe hypoglycemia in the Veterans Affairs Diabetes Trial (VADT)
Published in Cardiovascular diabetology (08-12-2021)“…Low C-peptide levels, indicating beta-cell dysfunction, are associated with increased within-day glucose variation and hypoglycemia. In advanced type 2…”
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Disialylated apolipoprotein C-III proteoform is associated with improved lipids in prediabetes and type 2 diabetes1[S]
Published in Journal of lipid research (01-05-2016)“…The apoC-III proteoform containing two sialic acid residues (apoC-III2) has different in vitro effects on lipid metabolism compared with asialylated…”
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The Association of Human Apolipoprotein C-III Sialylation Proteoforms with Plasma Triglycerides
Published in PloS one (03-12-2015)“…Apolipoprotein C-III (apoC-III) regulates triglyceride (TG) metabolism. In plasma, apoC-III exists in non-sialylated (apoC-III0a without glycosylation and…”
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Serum amyloid a truncations in type 2 diabetes mellitus
Published in PloS one (21-01-2015)“…Using mass spectrometric immunoassay, the abundance of SAA truncations relative to the native variants was examined in plasma of 91 participants with type 2…”
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Multimodal Distribution versus Logarithmic Transformation of Thyroid Volumes in Adolescents: Detection of Subgroup with Subclinical Thyroid Disorders and Its Impact on the Assessment of the Upper Limit of Normal Thyroid Volumes
Published in Endocrine Journal (01-04-2003)“…Our objective was to evaluate whether there is a multimodal distribution of thyroid volume (ThV) in iodinereplete adolescents and to examine the relation…”
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Adipogenic Human Adenovirus Ad‐36 Induces Commitment, Differentiation, and Lipid Accumulation in Human Adipose‐Derived Stem Cells
Published in Stem cells (Dayton, Ohio) (01-04-2008)“…Human adenovirus Ad‐36 is causatively and correlatively linked with animal and human obesity, respectively. Ad‐36 enhances differentiation of rodent…”
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Adipokine Protein Expression Pattern in Growth Hormone Deficiency Predisposes to the Increased Fat Cell Size and the Whole Body Metabolic Derangements
Published in The journal of clinical endocrinology and metabolism (01-06-2008)“…Context: GH deficiency (GHD) in adults is associated with central adiposity, dyslipidemia, and insulin resistance. Objective: The objective of the study was to…”
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Fish from industrially polluted freshwater as the main source of organochlorinated pollutants and increased frequency of thyroid disorders and dysglycemia
Published in Chemosphere (Oxford) (01-04-2007)“…In a certain area of Michalovce district in East Slovakia, heavy industrial pollution by polychlorinated biphenyls (PCBs) developed in 1955–1984 and very high…”
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Journal Article Conference Proceeding -
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Protein Array Reveals Differentially Expressed Proteins in Subcutaneous Adipose Tissue in Obesity
Published in Obesity (Silver Spring, Md.) (01-10-2007)“…Objective: Many adipokines, inflammatory cytokines, and other proteins produced by adipose tissue have been shown to be involved in the development of…”
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Thyroid ultrasound volume, structure and function after long-term high exposure of large population to polychlorinated biphenyls, pesticides and dioxin
Published in Chemosphere (Oxford) (01-08-2007)“…We examined 2046 adults (834 males and 1212 females aged 20–75 years) from polluted district in East Slovakia (POLL) and two neighboring upstream and upwind…”
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Possible effects of persistent organochlorinated pollutants cocktail on thyroid hormone levels and pituitary–thyroid interrelations
Published in Chemosphere (Oxford) (01-11-2007)“…In polluted district of Michalovce in East Slovakia (POLL) and two districts with background pollution (BCGR) 2046 adults (834 males and 1212 females aged…”
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The effect of insulin on net lipid oxidation predicts worsening of insulin resistance and development of type 2 diabetes mellitus
Published in American journal of physiology: endocrinology and metabolism (01-07-2007)“…Suppression of lipid oxidation (L(ox)) by insulin is impaired in obesity and type 2 diabetes mellitus (T2DM). Here we tested whether high L(ox) represents a…”
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Pancreatic Polypeptide Is Involved in the Regulation of Body Weight in Pima Indian Male Subjects
Published in Diabetes (New York, N.Y.) (01-12-2004)“…Pancreatic Polypeptide Is Involved in the Regulation of Body Weight in Pima Indian Male Subjects Juraj Koska 1 , Angelo DelParigi 1 , Barbora de Courten 2 ,…”
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